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contentuptodate· Content· item f15_30_15852

©2013 UpToDate ® Print Email Basic bisphosphonate chemical structure The two phosphonate (PO 3 ) groups covalently linked to carbon determine both the name "bisphosphonate" and the function. Bisphosphonates differ from each other at the two side chains, R 1 and R 2 , which determine their chemical properties and pharmacokinetics.