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©2013 UpToDate ® Print Email Substances possessing anticholinergic properties Class Examples Antihistamines Chlorpheniramine, Cyproheptadine, Doxylamine, Hydroxyzine, Diphenhydramine, Meclizine, Promethazine Neuroleptics Chlorpromazine, Clozapine, Mesoridazine, Olanzapine, Quetiapine, Thioridazine Tricyclic antidepressants Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Nortriptyline Antiparkinsonian drugs Trihexyphenidyl, Benztropine Ophthalmic drugs Atropine, Cyclopentolate Antispasmodics Clidinium, Dicyclomine, Hyoscyamine, Oxybutynin, Propantheline Plants Jimson Weed (Datura stramonium), Deady Nightshade (Atropa belladonna), Henbane (Hyoscyamus niger)