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abstractpubmed· Abstract· item 39496178
In symptomatic knee OA, adding oral methotrexate to usual analgesia reduced pain at 6 mo. Kingsbury SR, Tharmanathan P, Keding A, et al. Pain reduction with oral methotrexate in knee osteoarthritis: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2024;177:1145-1156. 39074374.