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Collagenous nodule mixed simple cyst and hemangioma coexistence in the liver. A 20-year-old female patient presented with two masses located in the left liver. In this patient, a computed tomography (CT) scan revealed a hypodense mass and a second well-defined mass with a calcified nodule in the left hepatic lobe. No enhancements were apparent in or around the masses. A laparotomy was performed due to the patient's symptoms, namely, the atypical CT findings and a risk of rupture of the subcapsular lesion. The operation revealed two masses in the left hepatic lobe and a left liver resection was subsequently performed. One of the masses involved segment III and the other mass was located in segment IV. The histopathologic findings supported a diagnosis of collagenous nodule mixed simple cyst and hemangioma. A diagnosis of collagenous nodule mixed simple hepatic cyst is extremely rare and radiologically mimics a teratoma, hepatolithiasis, parasitic cyst, or hemangioma. Although hepatic hemangiomas are the most common benign tumors found in the liver, the present case showed atypical radiographic features.