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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• A B cell follicle sanctuary permits persistent productive SIV infection in elite controllers Fukazawa Yoshinori 1Lum Richard 1Okoye34 passages
• A Brain Tumor Molecular Imaging Strategy30 passages
• A CD8 T cell transcription signature predicts prognosis in autoimmune disease McKinney23 passages
• A Fungal Glycosphingolipid Directly Activates Natural34 passages
• A Gpr120 Selective Agonist Improves Insulin Resistance and Chronic Inflammation Oh Da Young 1*Walenta Evelyn 1Akiyama25 passages
• A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolism Fafalios Arlee 1#Ma Jihong 1#Tan Xinping 1Stoops John 1Luo Jianhua 1DeFrances24 passages
• A KEY ROLE FOR OREXIN IN PANIC ANXIETY Johnson21 passages
• A Longitudinal Big Data Approach for Precision Health Rose Sophia Miryam Schüssler-Fiorenza 123*Contrepois Kévin 1*Moneghetti88 passages
• A MEK-independent role for CRAF in mitosis and tumor progression Mielgo Ainhoa 1Seguin Laetitia 1Huang Miller 1Camargo Maria Fernanda 1Anand Sudarshan 1Franovic Aleksandra 1Weis15 passages
• A Quantitative Basis for Antiretroviral Therapy for HIV-1 Infection Jilek20 passages
• A Signature of Circulating Inflammatory Proteins and Development of End Stage Renal Disease in Diabetes Niewczas66 passages
• A Single Dose of41 passages
• A VLP vaccine for epidemic Chikungunya virus protects non-human primates against infection Akahata Wataru 1Yang Zhi-yong 1Andersen Hanne 2Sun Siyang 3Holdaway23 passages
• A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis Dey Bappaditya 12Dey Ruchi Jain 1Cheung21 passages
• A branched chain amino acid metabolite drives vascular transport of fat and causes insulin resistance Jang Cholsoon 12*Oh31 passages
• A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis Johnson41 passages
• A genome-wide RNA interference screen reveals an essential CREB3L2/ATF5/MCL1 survival pathway in malignant glioma with therapeutic implications Sheng Zhi 1Li Li 2Zhu35 passages
• A high throughput drug screen for Entamoeba histolytica identifies a new lead and target Debnath Anjan 1Parsonage Derek 2Andrade28 passages
• A human memory T-cell subset with stem cell-like properties Gattinoni Luca 1*Lugli Enrico 2*Ji Yun 1Pos Zoltan 3Paulos32 passages
• A human monoclonal antibody prevents malaria infection and defines a new site of vulnerability on Plasmodium falciparum circumsporozoite protein Kisalu53 passages
• A liver HIF-2α/IRS2 pathway sensitizes hepatic insulin signaling and is modulated by VEGF inhibition Wei Kevin 1Piecewicz27 passages
• A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography Massoud28 passages
• A novel mechanism for glycoconjugate vaccine activation of the adaptive immune system Avci37 passages
• A novel, primate-specific, brain isoform of KCNH2 impacts cortical physiology, cognition, neuronal repolarization and risk for schizophrenia Huffaker42 passages
• A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q− syndrome Barlow38 passages
• A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis Imperial33 passages
• A public antibody lineage that potently inhibits malaria infection by dual binding to the circumsporozoite protein Tan Joshua 12*Sack37 passages
• A purine scaffold Hsp90 inhibitor destabilizes Bcl6 and has specific anti-tumor activity in Bcl6 dependent B-cell lymphomas Cerchietti32 passages
• A role for CNS PPARγ in the regulation of energy balance Ryan20 passages
• A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small cell lung cancer treated with PD-1 blockade47 passages
• A vital role for IL-2 trans-presentation in DC-mediated T cell activation in humans as revealed by daclizumab therapy Wuest32 passages
• ACF chromatin remodeling complex mediates stress–induced depressive–like behavior Sun HaoSheng 1Damez–Werno44 passages
• AICAR Prevents Heat Induced Sudden Death in RyR1 Mutant Mice Independent of AMPK Activation Lanner30 passages
• ALEFACEPT PROMOTES COSTIMULATION BLOCKADE BASED ALLOGRAFT SURVIVAL IN PRIMATES12 passages
• Abnormal development of NG2+PDGFRα+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model Carter35 passages
• Acquired EGFR C797S mediates resistance to AZD9291 in advanced non-small cell lung cancer harboring EGFR T790M Thress24 passages
• Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis Choi33 passages
• Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization Fan Di 1Coughlin39 passages
• Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification Regard35 passages
• Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases Russell20 passages
• Activation of neuronal P2X7 receptor-Pannexin-1 mediates death of enteric neurons during colitis Gulbransen23 passages
• Activin–like kinase–3 activity is important for kidney regeneration and reversal of fibrosis Sugimoto Hikaru 1LeBleu34 passages
• AdPLA ablation increases lipolysis and prevents obesity induced by high fat feeding or leptin deficiency Jaworski Kathy 12Ahmadian Maryam 12Duncan41 passages
• Adenovirus-Specific Immunity Following Immunization with an Ad5 HIV-1 Vaccine Candidate in9 passages
• Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche Maryanovich Maria 12Zahalka45 passages
• Age-related cancer mutations associated with clonal hematopoietic expansion Xie Mingchao 12*Lu Charles 1*Wang Jiayin 12*McLellan27 passages
• Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 Yousef Hanadie 12Czupalla133 passages
• Altered translation of GATA1 in Diamond-Blackfan anemia Ludwig39 passages
• Alternatively spliced VEGF receptor-2 is an essential endogenous inhibitor of lymphatic vessels Albuquerque40 passages
• Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering Thrane Vinita Rangroo 1235Thrane27 passages
• An abundant dysfunctional apolipoprotein A1 in human atheroma Huang Ying 1DiDonato53 passages
• An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer Xue Yaohua 12*Martelotto Luciano 312*Baslan Timour 4Vides Alberto 1Solomon Martha 1Mai Trang Thi 1Chaudhary Neelam 1Riely42 passages
• An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling Jun Heejin 1Yu Hui 12Gong Jianke 13Jiang Juan 14Qiao Xiaona 15Perkey Eric 678Kim Dong-il 1Emont49 passages
• An inhibitor of the protein kinases TBK1/IKKε improves obesity-related metabolic dysfunctions Reilly45 passages
• An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage Newman36 passages
• Anatomical Localization, Gene Expression Profiling, and Functional Characterization of Adult Human Neck Brown Fat Cypess23 passages
• Annotating MYC oncogene status with 89Zr-transferrin imaging Holland20 passages
• Antiretroviral dynamics determines HIV evolution and predicts therapy outcome Rosenbloom36 passages
• Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control Ranasinghe Srinika 1Cutler Sam 1Davis Isaiah 1Lu Richard 2Soghoian20 passages
• Aurora kinase A drives the evolution of resistance to third generation EGFR inhibitors in lung cancer Shah35 passages
• Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia Kentsis Alex 1Reed Casie 1Rice19 passages
• Autosomal-dominant immune dysregulation syndrome in humans with CTLA4 mutations Schubert Desirée 12Bode Claudia 1Kenefeck Rupert 3Hou Tie Zheng 3Wing32 passages
• BASOPHILS AND THE T HELPER 2 ENVIRONMENT CAN PROMOTE THE DEVELOPMENT OF LUPUS NEPHRITIS Charles Nicolas 1Hardwick Donna 2Daugas Eric 3Illei27 passages
• Baseline Ad5 serostatus does not predict Ad5-HIV vaccine-induced expansion of Ad-specific CD4+ T-cells Hutnick11 passages
• Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome70 passages
• Bitter taste receptors on airway smooth muscle bronchodilate by a localized calcium flux and reverse obstruction Deshpande28 passages
• Blockade of PDGFR-β Activation Eliminates Morphine Analgesic Tolerance Wang Yan 1+Barker Katherine 1+Shi Shanping 1Diaz Miguel 1Mo Bing 1*Gutstein13 passages
• Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors Du Yi 1Yamaguchi Hirohito 1Wei Yongkun 1Hsu49 passages
• Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction Nation57 passages
• Brain PPARγ Promotes Obesity and is Required for the Insulin–Sensitizing Effect of Thiazolidinediones Lu Min 1Sarruf23 passages
• Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity Bartelt Alexander 1*Widenmaier58 passages
• C-type lectin SIGNR1-mediated oral tolerance to food systemic anaphylaxis Zhou Yufeng 1*Kawasaki Hirokazu 1*Hsu Shih-Chang 1Lee33 passages
• CD22-CAR T Cells Induce Remissions in CD19-CAR Naïve and43 passages
• CD28 and ITK signals regulate autoreactive T cell trafficking Jain Nitya 1Miu Bing 1Jiang Jian-kang 2McKinstry33 passages
• CD47 Blockade Triggers T cell-mediated Destruction of Immunogenic Tumors Liu Xiaojuan 15Pu Yang 2Cron Kyle 2Deng Liufu 2Kline Justin 3Frazier43 passages
• COMPROMISED CDK1 ACTIVITY SENSITIZES BRCA-PROFICIENT CANCERS TO PARP INHIBITION Johnson Neil 12Li Yu-Chen 1Walton31 passages
• CSF-1R inhibition alters macrophage polarization and blocks glioma progression Pyonteck30 passages
• CT-based Biomarker Provides Unique Signature for Diagnosis of COPD Phenotypes and Disease Progression Galbán26 passages
• CX3CR1+ monocytes modulate learning and learning-dependent dendritic spine remodeling via TNFα Garré Juan Mauricio 1Silva Hernandez Moura 2Lafaille44 passages
• CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma Noll50 passages
• Cancer Cell-Selective In Vivo Near Infrared Photoimmunotherapy Targeting Specific Membrane Molecules Mitsunaga Makoto Ogawa Mikako Kosaka Nobuyuki Rosenblum25 passages
• Cancer cells exploit an orphan RNA to drive metastatic progression Fish Lisa 123Zhang Steven 123Yu Johnny 123Culbertson Bruce 123Zhou51 passages
• Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA13 Department of Internal81 passages
• Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg. 40, Room 4502, MSC-3005, 40 Convent Drive, Bethesda, 20892-300531 passages
• Center, University of Texas Southwestern Medical Center, Dallas, TXDepartment of Radiology, University of Texas Southwestern Medical Center, Dallas, TXGanji26 passages
• Center, University of Washington, Seattle,23 passages
• Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents Scarlett45 passages
• Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography29 passages
• Chloride extrusion enhancers as novel therapeutics for neurological diseases Gagnon Martin 123*Bergeron31 passages
• Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy43 passages
• Chronic variable stress activates hematopoietic stem cells Heidt Timo 1Sager31 passages
• Clinical Microfluidics for Neutrophil Genomics and Proteomics Kotz36 passages
• Clonal replacement of tumor-specific T cells following PD-1 blockade Yost63 passages
• Combination inhibition of PI3K and mTORC1 yields durable remissions in orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases Ni Jing 1211Ramkissoon26 passages
• Combined Vhl, Trp53 and Rb1 mutation causes clear cell renal cell carcinoma in mice Harlander Sabine 12Schönenberger Désirée 1Toussaint33 passages
• Commensal bacteria regulate TLR3-dependent inflammation following skin injury Lai Yuping 13Di Nardo Anna 13Nakatsuji Teruaki 13Leichtle Anke 23Yang Yan 4Cogen30 passages
• Commensal bacterial–derived signals regulate basophil hematopoiesis and allergic inflammation Hill41 passages
• Congenital Zika Virus Infection as a Silent Pathology With Loss of Neurogenic Output in the Fetal Brain Adams Waldorf37 passages
• Copy Number Analysis Indicates Monoclonal Origin of Lethal Metastatic Prostate Cancer Liu Wennuan ¶1Laitinen Sari ¶2Khan Sofia 3Vihinen Mauno 3Kowalski Jeanne 7Yu Guoqiang 8Chen Li 8Ewing29 passages
• Council (NHMRC)117387111027921145033Tong14 passages
• Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits Min Sang-Won 12#Chen Xu 12#Tracy53 passages
• Cyclophilin A enhances vascular oxidative stress and development of angiotensin II-induced aortic aneurysms Satoh Kimio 13Nigro Patrizia 1Matoba Tetsuya 1O'Dell32 passages
• DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia34 passages
• De novo NAD+ biosynthetic impairment in acute kidney injury in humans Mehr Ali Poyan 1*Tran54 passages
• Decreased Expression of Synapse-Related Genes and Loss of Synapses in Major Depressive Disorder31 passages
• Dectin-1 Activation on Macrophages by Galectin-9 Promotes Pancreatic Carcinoma and Peritumoral Immune-Tolerance Daley Donnele 1±Mani47 passages
• Defective Glucose Metabolism in Polycystic Kidney Disease30 passages
• Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome Lancaster34 passages
• Defective proviruses rapidly accumulate during acute HIV-1 infection Bruner25 passages
• Deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice Liu Jian 1Divoux Adeline 2Sun Jiusong 1Zhang Jie 1Clément Karine 2Glickman20 passages
• Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children. Nielsen-Saines24 passages
• Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin Liao Guey-Ying 1An Juan Ji 1Gharami Kusumika 1Waterhouse33 passages
• Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization Guo Nannan 123Soden57 passages
• Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome Santiago-Fernández Olaya 1Osorio26 passages
• Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential Roberts62 passages
• Diet and Maternal Gestational Weight Gain Predict Metabolic Maturation of Infant Gut Microbiomes Baumann-Dudenhoeffer51 passages
• Dietary Zinc Alters the Microbiota and Decreases Resistance to Clostridium difficile Infection Zackular30 passages
• Differential Glucose Requirement in Skin Homeostasis and Injury Identifies a Therapeutic Target for Psoriasis Zhang Zhuzhen 1Zi Zhenzhen *2Lee42 passages
• Differential regulation of myeloid leukemias by the bone marrow microenvironment Krause29 passages
• Direct Regulation of Blood Pressure by Smooth Muscle Cell Mineralocorticoid Receptors McCurley Amy 1Pires23 passages
• Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy Befroy27 passages
• Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization Korpal Manav 1Ell34 passages
• Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass Guan Min 1*Yao Wei 1*Liu Ruiwu 2Lam24 passages
• Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis Falcão Ana Mendanha 1van Bruggen David 1Marques Sueli 1Meijer Mandy 1Jäkel Sarah 2Agirre Eneritz 1Samudyata 1Floriddia51 passages
• Dissolving Polymer Microneedle Patches for Influenza Vaccination Sullivan32 passages
• Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia Li Sheng *12Garrett-Bakelman55 passages
• Down-regulation of CD4 by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection Beaumier31 passages
• Dual and opposing roles of primary cilia in medulloblastoma development Han Young-Goo 1Kim Hong Joo 2Dlugosz17 passages
• Dual roles for hepatic lectin receptors in the clearance of chilled platelets Rumjantseva Viktoria 12Grewal37 passages
• Dynamic NETosis is Carried Out by Live Neutrophils in Human and Mouse Bacterial Abscesses and During Severe Gram-Positive Infection Yipp48 passages
• Dynamic regulation of cardiolipin by the lipid pump, ATP8b1, determines the severity of lung injury in experimental bacterial pneumonia Ray32 passages
• Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division Dumont41 passages
• Early life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues Thome21 passages
• Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in newborn macaques Hessell37 passages
• Effective Use of PI3K and MEK Inhibitors to Treat19 passages
• Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10 Sun Jie 1Madan Rajat 2Karp34 passages
• Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge Hansen19 passages
• Efficient Hepatitis C Virus Particle Formation Requires Diacylglycerol Acyltransferase 1 (DGAT1) Herker Eva 123Harris Charles 234Hernandez Céline 5Carpentier Arnaud 5Kaehlcke Katrin 1Rosenberg14 passages
• Elevated circulating branched chain amino acids are an early event in pancreatic adenocarcinoma development Mayers58 passages
• Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood Tata Brooke 12El Houda Mimouni Nour 12Barbotin Anne-Laure 13Malone72 passages
• Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections Dalli Jesmond 1Chiang Nan 1Serhan34 passages
• Endogenous antigen processing drives the primary CD4+ T cell response to influenza Miller43 passages
• Engineered bacteriophages for treatment of a patient with a disseminated drug resistant Mycobacterium abscessus Dedrick22 passages
• Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer Patten49 passages
• Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors Cejas Paloma 123*Drier Yotam 45*§¶Dreijerink31 passages
• Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury Doan45 passages
• Epigenetic expansion of VHL-HIF signal output drives multi-organ metastasis in renal cancer Vanharanta Sakari 1Shu Weiping 1Brenet Fabienne 2Hakimi A. Ari 34Heguy Adriana 5Viale Agnes 6Reuter45 passages
• Epigenetic regulation of synaptic remodeling in stress disorders Golden27 passages
• Epigenetic suppression of GAD65 expression mediates persistent pain Zhang Zhi Cai Youqing Zou Fang Bie Bihua Pan34 passages
• Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits You29 passages
• Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition Tang Yujie 12Gholamin Sharareh 2Schubert Simone 12Willardson46 passages
• Epithelial to Mesenchymal Transition induces cell cycle arrest and parenchymal damage in renal fibrosis Lovisa Sara 1*LeBleu44 passages
• Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 Xu Kai 1*Acharya Priyamvada 12*Kong Rui 1*Cheng Cheng 1*Chuang Gwo-Yu 1Liu Kevin 1Louder63 passages
• Essential Role for Autophagy in the Maintenance of Immunological Memory Against Influenza Infection Chen Min 1*Hong Monica Jeongsoo 2Sun Huanhuan 1Wang Lei 1Shi Xiurong 1Gilbert46 passages
• Essential Staphylococcus aureus toxin export system Chatterjee18 passages
• Excess TGF-β mediates muscle weakness associated with bone metastases in mice Waning64 passages
• Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models Lourenco70 passages
• Experimental Microbial Dysbiosis Does Not Promote Disease Progression in SIV-Infected Macaques Ortiz25 passages
• Extracellular histones are major mediators of death in sepsis Xu Jun 1Zhang Xiaomei 2Pelayo Rosana 3Monestier Marc 4Ammollo17 passages
• FGF21 contributes to neuroendocrine control of female reproduction Owen20 passages
• Fast degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neo-artery Wu Wei 12Allen31 passages
• Fetal gene therapy for neurodegenerative disease of infants Massaro Giulia 1Mattar41 passages
• Follicular regulatory T (Tfr) cells with dual Foxp3 and Bcl6 expression suppress germinal center reactions Chung Yeonseok 13Tanaka Shinya 1Chu Fuliang 2Nurieva Roza 1Martinez29 passages
• Foundation, New Orleans, LA 70130, USACorrespondence should be addressed to: Seulki Lee, Ph.D., The38 passages
• Foxp3+ follicular regulatory T cells control T follicular helper cells and the germinal center response Linterman32 passages
• Functionally-defined Therapeutic Targets in Diffuse Intrinsic Pontine55 passages
• GM-CSF and CXCR4 Define a T Helper Cell Signature in Multiple Sclerosis Galli Edoardo 1†Hartmann58 passages
• GOAT links dietary lipids with the endocrine control of energy balance22 passages
• Gain-of-function mutation of microRNA-140 in human skeletal dysplasia Grigelioniene Giedre 12315Suzuki69 passages
• Gamma-secretase inhibitors reverse glucocorticoid resistance in T-ALL Real31 passages
• Generation of a novel therapeutic peptide that depletes MDSC in tumor-bearing mice Qin Hong 15*Lerman Beatrisa 15*Sakamaki Ippei 15*Wei Guowei 15Cha Soungchul 15Rao27 passages
• Genetic and Acute CPEB Depletion Ameliorate20 passages
• Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed anti-diabetic target in mice selected for leanness Morton55 passages
• Genetic impact of vaccination on breakthrough HIV-1 sequences from the Step trial Rolland Morgane 1*Tovanabutra Sodsai 2*deCamp27 passages
• Genetically-engineered human cortical spheroid models of Tuberous Sclerosis Blair57 passages
• Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women McKinnon24 passages
• Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo Gammage26 passages
• Genome-wide Association Study of Peripheral Artery Disease in the Million Veteran Program Klarin59 passages
• Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular-fibrosis and tumor progression Laklai Hanane 1Miroshnikova47 passages
• Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease Lees41 passages
• Glutamate Release by Primary Brain Tumors Induces Epileptic Activity Buckingham30 passages
• Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and target for cancer immunotherapy Logtenberg78 passages
• Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow Bowers Emily 12Slaughter Anastasiya 1Frenette36 passages
• HETEROTYPIC INTERACTIONS ENABLED BY POLARIZED NEUTROPHIL MICRODOMAINS MEDIATE THROMBO-INFLAMMATORY INJURY Hidalgo Andrés *‡Chang Jungshan *Jang Jung-Eun *Peired34 passages
• HIV persistence in tissue macrophages of humanized myeloid only mice during antiretroviral therapy26 passages
• HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders Janes Holly 1Herbeck20 passages
• HIV-1 persistence in CD4+ T cells with stem cell-like properties Buzon19 passages
• Healthy infants harbor intestinal bacteria that protect against food allergy Feehley Taylor 1Plunkett40 passages
• Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration Sun Zheng 1Miller33 passages
• Hepatitis C Virus Infection Activates a Novel Innate Pathway Involving IKKα in Lipogenesis and Viral Assembly Li Qisheng Pène Véronique Krishnamurthy Siddharth Cha Helen41 passages
• Highly efficient therapeutic gene editing of human hematopoietic stem cells Wu Yuxuan 12*Zeng Jing 1*Roscoe50 passages
• Homeostatic regulation of T cell trafficking by a B cell derived peptide is impaired in autoimmune and chronic inflammatory disease Chimen Myriam 1McGettrick63 passages
• Hospital, Memphis, 3810524 passages
• Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co–therapy Li Feng 1Lu Jie 1Cheng Jie 2Wang Laiyou 13Matsubara Tsutomu 2Csanaky Iván L. 1Klaassen13 passages
• Human Primary Liver Cancer -derived Organoid Cultures for disease modelling and drug screening Broutier Laura 1Mastrogiovanni Gianmarco 13Verstegen66 passages
• Hyperglycemia Induced Cerebral Hematoma Expansion is Mediated by Plasma Kallikrein Liu Jia 14Gao Ben-Bo 14Clermont22 passages
• Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle Bellinger23 passages
• Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance López Miguel 123Varela Luis 12Vázquez María J. 12Rodríguez-Cuenca Sergio 3González31 passages
• IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure Lu62 passages
• IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity Kim Hye Young 1Lee Hyun Jun 1*Chang Ya-Jen 1**Pichavant Muriel 1Shore33 passages
• IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction Kudo Makoto 123Melton31 passages
• IL-25 induces type 2 cytokine production in a novel, steroid resistant IL-17RB+ myeloid population that exacerbates asthmatic pathology Petersen31 passages
• IRF3 and Type I Interferons Fuel a Fatal Response to Myocardial Infarction King38 passages
• Identification of a central role for complement in osteoarthritis Wang Qian 12*Rozelle16 passages
• Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Swarup Vivek 111Hinz94 passages
• Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts Frésard Laure 1*Smail Craig 2Ferraro45 passages
• Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor Sainz Bruno Jr.1†Barretto Naina 1Martin22 passages
• Imaging the Subcellular Structure of Human Coronary Atherosclerosis Using 1-μm Resolution Optical Coherence Tomography (μOCT) Liu Linbo 12Gardecki22 passages
• Imatinib potentiates anti-tumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido Balachandran30 passages
• Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes Clatworthy32 passages
• Immunogenic neoantigens derived from gene fusions stimulate T cell responses Yang Wei 12†Lee Ken-Wing 1†Srivastava55 passages
• Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways Bhargava Prerna 1Li Changlin 2Stanya30 passages
• Impact of Pre-adapted HIV Transmission Carlson93 passages
• In Vivo Imaging of Ligand Receptor Binding with Gaussia Luciferase Complementation Luker21 passages
• In utero CRISPR-mediated therapeutic editing of metabolic genes Rossidis33 passages
• In vivo Prevention of Transplant Arteriosclerosis by ex vivo Expanded Human20 passages
• In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation Panizzi Peter PhD123Nahrendorf22 passages
• Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity but does not contribute to sarcopenia Fry20 passages
• Induction of human pancreatic beta cell replication by inhibitors of dual specificity tyrosine regulated kinase Wang Peng PhD12Alvarez-Perez Juan-Carlos PhD12Felsenfeld35 passages
• Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection Grainger49 passages
• Inflammatory signaling in human Tuberculosis granulomas is spatially organized Marakalala29 passages
• Inhibition of JAK/STAT signaling stimulates adult satellite cell function Price39 passages
• Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1–dependent manner Pajvani32 passages
• Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability Pajvani24 passages
• Inhibition of TGF–β signaling in subchondral bone mesenchymal stem cells attenuates osteoarthritis Zhen Gehua 12Wen Chunyi 67Jia Xiaofeng 3Li Yu 8Crane35 passages
• Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small cell lung cancer in preclinical models Svensson53 passages
• Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer Camarda Roman 12Zhou Zhou 1Kohnz37 passages
• Inhibition of gut-derived serotonin synthesis: a potential bone anabolic treatment Yadav21 passages
• Inhibition of p300 impairs Foxp3+ T-regulatory cell function and promotes anti-tumor immunity Liu Yujie 1†Wang Liqing 1†Predina Jarrod 2Han Rongxiang 1Beier26 passages
• Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency Liang Yu 1Vogel23 passages
• Inhibitors of Leucine Rich Repeat Kinase 2 (LRRK2) Protect Against LRRK2-Models of Parkinson’s Disease Lee Byoung Dae 12Shin Joo-Ho 12VanKampen Jackalina 3Petrucelli Leonard 3West12 passages
• Institute, La Jolla, 9203711 passages
• Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1 Lu Mingjian 1Wan Min 1Leavens38 passages
• Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression Desgrosellier34 passages
• Interleukin-1β promotes atheroprotective changes of advanced atherosclerotic lesions in mice Gomez Delphine 1234Baylis41 passages
• Interleukin-35 Induces33 passages
• Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis Koeth56 passages
• Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo Yoo Hongki 19Kim Jin Won 239Shishkov Milen 1Namati Eman 1Morse Theodore 4Shubochkin Roman 4McCarthy22 passages
• Intracellular Calcium Regulates Nonsense-Mediated mRNA Decay Nickless Andrew 1Jackson Erin 2Marasa Jayne 2Nugent Patrick 1Mercer31 passages
• Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis58 passages
• Invasive 3-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia Ridky23 passages
• Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis Roepke36 passages
• Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease Youm Yun-Hee 1*Nguyen29 passages
• Kynurenine–3–monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis Mole53 passages
• LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity Li Pingping 13Oh Da Young 1Bandyopadhyay Gautam 1Lagakos42 passages
• Laboratory, Fondazione IRCCS Ospedale Maggiore Policlinico &44 passages
• Lack of antibody affinity maturation due to poor Toll stimulation led to enhanced RSV disease Delgado Maria Florencia 1Coviello Silvina 1Monsalvo A. Clara 1Melendi35 passages
• Large intestine-targeted nanoparticle-releasing oral vaccine to control genitorectal viral infection Zhu Qing 12Talton James 3Zhang Guofeng 4Cunningham Tshaka 1Wang Zijian 5Waters27 passages
• Lethal inflammasome activation by a multi-drug resistant pathobiont upon antibiotic disruption of the microbiota Ayres49 passages
• Lipid accumulation and dendritic cell dysfunction in cancer Herber32 passages
• Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers Parikh31 passages
• Local proliferation dominates lesional macrophage accumulation in atherosclerosis Robbins25 passages
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