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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• (untitled)1 passage
• 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study.1 passage
• 1-year outcomes with the Absorb bioresorbable scaffold in patients with coronary artery disease: a patient-level, pooled meta-analysis.1 passage
• 10 years of health-care reform in China: progress and gaps in Universal Health Coverage.1 passage
• 11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial.1 passage
• 140 mmol/L of sodium versus 77 mmol/L of sodium in maintenance intravenous fluid therapy for children in hospital (PIMS): a randomised controlled double-blind trial.1 passage
• 2 year neurodevelopmental and intermediate perinatal outcomes in infants with very preterm fetal growth restriction (TRUFFLE): a randomised trial.1 passage
• 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial.1 passage
• 2-year outcomes with the Absorb bioresorbable scaffold for treatment of coronary artery disease: a systematic review and meta-analysis of seven randomised trials with an individual patient data substudy.1 passage
• 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial.1 passage
• 40-year trends in an index of survival for all cancers combined and survival adjusted for age and sex for each cancer in England and Wales, 1971-2011: a population-based study.1 passage
• 40th anniversary of the WHO International Code of Marketing of Breastmilk Substitutes.1 passage
• 5 year mortality predictors in 498,103 UK Biobank participants: a prospective population-based study.1 passage
• 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial.1 passage
• 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial.1 passage
• 5-year results of accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy versus whole-breast irradiation with boost after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: a randomised, phase 3, non-inferiority trial.1 passage
• 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.1 passage
• 6 months versus 12 months of adjuvant trastuzumab in early breast cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial.1 passage
• 6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial.1 passage
• 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study.1 passage
• 6-month versus 12-month or longer dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (SMART-DATE): a randomised, open-label, non-inferiority trial.1 passage
• A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial.1 passage
• A bioresorbable everolimus-eluting scaffold versus a metallic everolimus-eluting stent for ischaemic heart disease caused by de-novo native coronary artery lesions (ABSORB II): an interim 1-year analysis of clinical and procedural secondary outcomes from a randomised controlled trial.1 passage
• A blood RNA signature for tuberculosis disease risk: a prospective cohort study.1 passage
• A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension.1 passage
• A cleaner burning biomass-fuelled cookstove intervention to prevent pneumonia in children under 5 years old in rural Malawi (the Cooking and Pneumonia Study): a cluster randomised controlled trial.1 passage
• A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA.1 passage
• A community empowerment approach to the HIV response among sex workers: effectiveness, challenges, and considerations for implementation and scale-up.1 passage
• A community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial.1 passage
• A comparison of health expectancies over two decades in England: results of the Cognitive Function and Ageing Study I and II.1 passage
• A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial.1 passage
• A comparison of two hybrid closed-loop systems in adolescents and young adults with type 1 diabetes (FLAIR): a multicentre, randomised, crossover trial.1 passage
• A comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study.1 passage
• A contemporary simple risk score for prediction of contrast-associated acute kidney injury after percutaneous coronary intervention: derivation and validation from an observational registry.1 passage
• A cross-sectional survey of the prevalence and determinants of comorbid psychological distress in attendees at two general hospitals in Gaza.1 passage
• A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.1 passage
• A global assessment of civil registration and vital statistics systems: monitoring data quality and progress.1 passage
• A medical-toxicological view of tattooing.1 passage
• A multicountry health partnership programme to establish sustainable trauma training in east, central, and southern African countries using a cascading trauma management course model.1 passage
• A multidimensional measure of wellbeing among youth: a cross-sectional study of the Palestinian refugee youth in Lebanon.1 passage
• A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial.1 passage
• A polymer-coated, paclitaxel-eluting stent (Eluvia) versus a polymer-free, paclitaxel-coated stent (Zilver PTX) for endovascular femoropopliteal intervention (IMPERIAL): a randomised, non-inferiority trial.1 passage
• A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial.1 passage
• A presurgical window-of-opportunity study of metformin in obesity-driven endometrial cancer.1 passage
• A qualitative study exploring contextual challenges to surgical care provision in 21 LMICs.1 passage
• A rapid evidence review of the effectiveness and cost-effectiveness of alcohol control policies: an English perspective.1 passage
• A retrospective and prospective analysis of the west African Ebola virus disease epidemic: robust national health systems at the foundation and an empowered WHO at the apex.1 passage
• A risk-based approach is best for decision making on holding mass gathering events.1 passage
• A role for helminth parasites in achieving immunological tolerance in transplantation.1 passage
• A scalable, integrated intervention to engage people who inject drugs in HIV care and medication-assisted treatment (HPTN 074): a randomised, controlled phase 3 feasibility and efficacy study.1 passage
• A sirolimus-eluting bioabsorbable polymer-coated stent (MiStent) versus an everolimus-eluting durable polymer stent (Xience) after percutaneous coronary intervention (DESSOLVE III): a randomised, single-blind, multicentre, non-inferiority, phase 3 trial.1 passage
• A time-driven activity-based costing model to improve health-care resource use in Mirebalais, Haiti.1 passage
• A tobacco-free world: a call to action to phase out the sale of tobacco products by 2040.1 passage
• A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial.1 passage
• Abortion incidence between 1990 and 2014: global, regional, and subregional levels and trends.1 passage
• Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.1 passage
• Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial.1 passage
• Accelerate progress-sexual and reproductive health and rights for all: report of the Guttmacher-Lancet Commission.1 passage
• Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial.1 passage
• Access to effective antimicrobials: a worldwide challenge.1 passage
• Access to pathology and laboratory medicine services: a crucial gap.1 passage
• Access to water and morbidity in children in the occupied Palestinian territory, 2000-14: a repeated cross-sectional study.1 passage
• Accuracy of PECARN, CATCH, and CHALICE head injury decision rules in children: a prospective cohort study.1 passage
• Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials.1 passage
• Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system.1 passage
• Achieving universal health coverage in France: policy reforms and the challenge of inequalities.1 passage
• Action to address the household economic burden of non-communicable diseases.1 passage
• Active case finding with case management: the key to tackling the COVID-19 pandemic.1 passage
• Active surveillance for asymptomatic colonisation by multidrug-resistant bacteria in patients transferred to a tertiary care hospital in the occupied Palestinian territory.1 passage
• Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase.1 passage
• Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management.1 passage
• Acute bacterial meningitis in adults.1 passage
• Acute encephalitis in immunocompetent adults.1 passage
• Acute flaccid myelitis: cause, diagnosis, and management.1 passage
• Acute kidney injury in China: a cross-sectional survey.1 passage
• Acute kidney injury.1 passage
• Acute liver failure.1 passage
• Acute lymphoblastic leukaemia.1 passage
• Acute myeloid leukaemia.1 passage
• Acute myocardial infarction.1 passage
• Acute pancreatitis.2 passages
• Acute poisoning in the Gaza Strip: a retrospective study.1 passage
• Acute respiratory distress syndrome.2 passages
• Acute rheumatic fever.1 passage
• Acute-on-chronic liver failure.1 passage
• Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.1 passage
• Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial.1 passage
• Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial.1 passage
• Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.1 passage
• Addition of high-dose cytarabine to immunochemotherapy before autologous stem-cell transplantation in patients aged 65 years or younger with mantle cell lymphoma (MCL Younger): a randomised, open-label, phase 3 trial of the European Mantle Cell Lymphoma Network.1 passage
• Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.1 passage
• Addressing the fragmentation of global health: the Lancet Commission on synergies between universal health coverage, health security, and health promotion.1 passage
• Addressing violence against women: a call to action.1 passage
• Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial.1 passage
• Adenovirus respiratory tract infections in infants: a retrospective chart-review study.1 passage
• Adhesion-related readmissions after open and laparoscopic surgery: a retrospective cohort study (SCAR update).1 passage
• Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial.1 passage
• Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study.1 passage
• Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Adjustable intragastric balloon for treatment of obesity: a multicentre, open-label, randomised clinical trial.1 passage
• Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB-IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial.1 passage
• Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials.1 passage
• Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial.1 passage
• Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01).1 passage
• Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Adjuvant nivolumab plus ipilimumab or nivolumab monotherapy versus placebo in patients with resected stage IV melanoma with no evidence of disease (IMMUNED): a randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data.1 passage
• Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial.1 passage
• Adrenal insufficiency.1 passage
• Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series.1 passage
• Adult spinal deformity.1 passage
• Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial.1 passage
• Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity.1 passage
• Advances in nutrition of the newborn infant.1 passage
• Advances in paediatric gastroenterology.1 passage
• Advances in paediatric urology.1 passage
• Advances in technology for management of type 1 diabetes.1 passage
• Advances in the treatment of advanced oestrogen-receptor-positive breast cancer.1 passage
• Advances in β-cell replacement therapy for the treatment of type 1 diabetes.1 passage
• Adverse events after first, single, mesh and non-mesh surgical procedures for stress urinary incontinence and pelvic organ prolapse in Scotland, 1997-2016: a population-based cohort study.1 passage
• Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase.1 passage
• Adverse outcomes after arthroscopic partial meniscectomy: a study of 700 000 procedures in the national Hospital Episode Statistics database for England.1 passage
• Adverse pregnancy outcomes attributable to socioeconomic and ethnic inequalities in England: a national cohort study.1 passage
• Advising women with diabetes in pregnancy to express breastmilk in late pregnancy (Diabetes and Antenatal Milk Expressing [DAME]): a multicentre, unblinded, randomised controlled trial.1 passage
• Age-related macular degeneration.1 passage
• Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study.1 passage
• Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis.1 passage
• Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.1 passage
• Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.1 passage
• Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Alcohol use disorders.2 passages
• Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial.1 passage
• Alzheimer's disease.2 passages
• Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial.1 passage
• Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial.1 passage
• Amyotrophic lateral sclerosis.1 passage
• An action agenda for HIV and sex workers.1 passage
• An analysis of out-of-pocket costs associated with hospitalised injuries in Vietnam.1 passage
• An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction.1 passage
• An estimate of hernia prevalence in Nepal from a countrywide community survey.1 passage
• An evaluation of the effects of lowering blood alcohol concentration limits for drivers on the rates of road traffic accidents and alcohol consumption: a natural experiment.1 passage
• An evidence-based assessment of the impact of the Olympic Games on population levels of physical activity.1 passage
• An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial.1 passage
• An intensified dosing schedule of subcutaneous methotrexate in patients with moderate to severe plaque-type psoriasis (METOP): a 52 week, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (PRIMIT): a primary care randomised trial.1 passage
• An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study.1 passage
• An update on Zika virus infection.1 passage
• Anacetrapib as lipid-modifying therapy in patients with heterozygous familial hypercholesterolaemia (REALIZE): a randomised, double-blind, placebo-controlled, phase 3 study.1 passage
• Anaesthetic depth and complications after major surgery: an international, randomised controlled trial.1 passage
• Anal incontinence after caesarean and vaginal delivery in Sweden: a national population-based study.1 passage
• Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial.1 passage
• Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm.1 passage
• Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial.1 passage
• Anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ undergoing lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial.1 passage
• Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial.1 passage
• Anti-D immunoglobulin versus immunoglobulin G for the treatment of acute immune thrombocytopenia in children: a 10-year retrospective study.1 passage
• Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial.1 passage
• Anti-cancer effects of oncolytic viral therapy combined with photodynamic therapy in human pancreatic cancer cell lines.1 passage
• Antiangiogenic therapy in oncology: current status and future directions.1 passage
• Antibiotic allergy.1 passage
• Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation.1 passage
• Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial.1 passage
• Antibiotic use in acute upper respiratory tract infections and uncomplicated lacerations in the Gaza Strip: clinical audit and re-audit.1 passage
• Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial.1 passage
• Antibody-drug conjugates for cancer.1 passage
• Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.1 passage
• Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.1 passage
• Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials.1 passage
• Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.1 passage
• Anxiety disorders.1 passage
• Anxiety.1 passage
• Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium.1 passage
• Applying feminist theory to medical education.1 passage
• Are gender gaps due to evaluations of the applicant or the science? A natural experiment at a national funding agency.1 passage
• Are high-performing health systems resilient against the COVID-19 epidemic?1 passage
• Are well functioning civil registration and vital statistics systems associated with better health outcomes?1 passage
• Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a prospective diagnostic study.1 passage
• Armed conflict and child mortality in Africa: a geospatial analysis.1 passage
• Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials.1 passage
• Arsenic, antimony, and Leishmania: has arsenic contamination of drinking water in India led to treatment- resistant kala-azar?1 passage
• Arterial hypertension.1 passage
• Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial.1 passage
• Artificial intelligence and the future of global health.1 passage
• Aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion (COMPASS): a multicentre, randomised, open label, blinded outcome, non-inferiority trial.1 passage
• Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.1 passage
• Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial.1 passage
• Assessment of caesarean section and inguinal hernia repair as proxy indicators of total number of surgeries.1 passage
• Assessment of drug interactions and their associated factors among patients with cardiovascular diseases: a cross-sectional study from the occupied Palestinian territory.1 passage
• Assessment of economic vulnerability to infectious disease crises.1 passage
• Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.1 passage
• Assessment of glycogen phosphorylase isoenzyme BB as a biomarker for pre-eclampsia and small for gestational age.1 passage
• Assessment of health-related quality of life in patients with inflammatory bowel disease in occupied Palestinian territory: a correlation cross-sectional study.1 passage
• Assessment of pain control among patients with cancer in hospitals of the Gaza Strip: a cross-sectional study.1 passage
• Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study.1 passage
• Assessment of the influence of Facebook on eating out at fast food restaurants: a cross-sectional study of Palestinian college students.1 passage
• Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak.1 passage
• Assessment of the surveillance system for adverse events following immunisation in the Gaza Strip: a cross-sectional study.1 passage
• Association between Zika virus and microcephaly in French Polynesia, 2013-15: a retrospective study.1 passage
• Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials.1 passage
• Association between air pollution and coronary artery calcification within six metropolitan areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): a longitudinal cohort study.1 passage
• Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial.1 passage
• Association between interpregnancy interval and adverse birth outcomes in women with a previous stillbirth: an international cohort study.1 passage
• Association between urinary dickkopf-3, acute kidney injury, and subsequent loss of kidney function in patients undergoing cardiac surgery: an observational cohort study.1 passage
• Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses.1 passage
• Association of anti-carbamylated protein antibodies with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.1 passage
• Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study.1 passage
• Association of metabolic-bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants.1 passage
• Associations between stressful working conditions and psychosomatic symptoms among Palestinian nurses: a cross-sectional survey.1 passage
• Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study.1 passage
• Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies.1 passage
• Assuring health coverage for all in India.1 passage
• Asthma.1 passage
• Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial.1 passage
• Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.1 passage
• Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial.1 passage
• Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.1 passage
• Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial.1 passage
• Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.1 passage
• Atezolizumab with or without chemotherapy in metastatic urothelial cancer (IMvigor130): a multicentre, randomised, placebo-controlled phase 3 trial.1 passage
• Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAF1 passage
• Atopic dermatitis.2 passages
• Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.1 passage
• Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis.1 passage
• Attacks against health care in Syria, 2015-16: results from a real-time reporting tool.1 passage
• Attention deficit hyperactivity disorder.1 passage
• Attention-deficit hyperactivity disorder.1 passage
• Autism spectrum disorder.1 passage
• Automated insulin dosing guidance to optimise insulin management in patients with type 2 diabetes: a multicentre, randomised controlled trial.1 passage
• Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trial.1 passage
• Autosomal dominant polycystic kidney disease.1 passage
• Autosomal dominant polycystic kidney disease: the changing face of clinical management.1 passage
• Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data.1 passage
• Availability, cost, and prescription patterns of antihypertensive medications in primary health care in China: a nationwide cross-sectional survey.1 passage
• Averting a malaria disaster: will insecticide resistance derail malaria control?1 passage
• Avoiding 40% of the premature deaths in each country, 2010-30: review of national mortality trends to help quantify the UN sustainable development goal for health.1 passage
• Awareness and factors influencing breast reconstruction in the Gaza Strip: a cross-sectional study.1 passage
• Awareness and prevalence of needle stick injuries among cleaners and health-care providers in Gaza Strip hospitals: a cross-sectional study.1 passage
• Awareness of fetal movements and care package to reduce fetal mortality (AFFIRM): a stepped wedge, cluster-randomised trial.1 passage
• Axial spondyloarthritis.1 passage
• Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.1 passage
• Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.1 passage
• Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.1 passage
• Bariatric-metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial.1 passage
• Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial.1 passage
• Barriers preventing Palestinian women from having a mammogram: a qualitative study.1 passage
• Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials.1 passage
• Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health.1 passage
• Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.1 passage
• Benefits and harms of screening men for abdominal aortic aneurysm in Sweden: a registry-based cohort study.1 passage
• Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial.1 passage
• Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240).1 passage
• Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label, phase 3 trial.1 passage
• Beyond pharmacological treatment: an insight into therapies that target specific aspects of heart failure pathophysiology.1 passage
• Beyond too little, too late and too much, too soon: a pathway towards evidence-based, respectful maternity care worldwide.1 passage
• Bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection (GS-US-380-1489): a double-blind, multicentre, phase 3, randomised controlled non-inferiority trial.1 passage
• Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial.1 passage
• Biliary tract cancer.1 passage
• Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial.1 passage
• Bimekizumab in patients with active psoriatic arthritis: results from a 48-week, randomised, double-blind, placebo-controlled, dose-ranging phase 2b trial.1 passage
• Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial.1 passage
• Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in patients with ST-segment elevation myocardial infarction (BIOSTEMI): a single-blind, prospective, randomised superiority trial.1 passage
• Bioengineered human acellular vessels for dialysis access in patients with end-stage renal disease: two phase 2 single-arm trials.1 passage
• Bionic reconstruction to restore hand function after brachial plexus injury: a case series of three patients.1 passage
• Biopsy transcriptome expression profiling to identify kidney transplants at risk of chronic injury: a multicentre, prospective study.1 passage
• Bipolar disorder.1 passage
• Bipolar disorders.1 passage
• Bladder cancer.1 passage
• Blinded outcomes and angina assessment of coronary bioresorbable scaffolds: 30-day and 1-year results from the ABSORB IV randomised trial.1 passage
• Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis.1 passage
• Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.1 passage
• Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.1 passage
• Body-mass index and diabetes risk in 57 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 685 616 adults.1 passage
• Body-mass index and obesity in urban and rural China: findings from consecutive nationally representative surveys during 2004-18.1 passage
• Borderline personality disorder.1 passage
• Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial.1 passage
• Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study.1 passage
• Brain injury after cardiac arrest.1 passage
• Brazil's unified health system: the first 30 years and prospects for the future.1 passage
• Breakdown of simple female genital fistula repair after 7 day versus 14 day postoperative bladder catheterisation: a randomised, controlled, open-label, non-inferiority trial.1 passage
• Breast cancer.2 passages
• Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect.1 passage
• Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Brentuximab vedotin or physician's choice in CD30-positive cutaneous T-cell lymphoma (ALCANZA): an international, open-label, randomised, phase 3, multicentre trial.1 passage
• Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.1 passage
• Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial.1 passage
• Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials.1 passage
• Bronchiectasis in children: diagnosis and treatment.1 passage
• Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial.1 passage
• Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial.1 passage
• Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial.1 passage
• Building evidence and measuring clinical outcomes for genomic medicine.1 passage
• Building the case for embedding global health security into universal health coverage: a proposal for a unified health system that includes public health.1 passage
• Building the foundations for sustainable development: a case for global investment in the capabilities of adolescents.1 passage
• Burden of disease in Brazil, 1990-2016: a systematic subnational analysis for the Global Burden of Disease Study 2016.1 passage
• Burden of road traffic injuries in Nepal: results of a countrywide population-based survey.1 passage
• Burosumab versus conventional therapy in children with X-linked hypophosphataemia: a randomised, active-controlled, open-label, phase 3 trial.1 passage
• CD4+CD28- T-cell expansions in ANCA-associated vasculitis and association with arterial stiffness: baseline data from a randomised controlled trial.1 passage
• CD57 expression in CD8 T cells and development of cutaneous squamous cell carcinoma in renal transplant recipients: a prospective cohort study.1 passage
• COVID-19 and Italy: what next?1 passage
• COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study.1 passage
• COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England.1 passage
• COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.1 passage
• COVID-19: the case for health-care worker screening to prevent hospital transmission.1 passage
• CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial.1 passage
• Caesarean section surgical techniques: 3 year follow-up of the CORONIS fractional, factorial, unmasked, randomised controlled trial.1 passage
• Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial.1 passage
• Call to action: how can the US Ending the HIV Epidemic initiative succeed?1 passage
• Can encapsulated glutamine increase GLP-1 secretion, improve glucose tolerance, and reduce meal size in healthy volunteers? A randomised, placebo-controlled, cross-over trial.1 passage
• Can macrophages within the microenvironment of locally invasive rectal cancers predict response to radiotherapy?1 passage
• Can mass media interventions reduce child mortality?1 passage
• Canada's global health role: supporting equity and global citizenship as a middle power.1 passage
• Canada's universal health-care system: achieving its potential.1 passage
• Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial.1 passage
• Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial.1 passage
• Cannabis use and treatment resistance in first episode psychosis: a natural language processing study.1 passage
• Carbohydrate quality and human health: a series of systematic reviews and meta-analyses.1 passage
• Cardiopulmonary resuscitation in special circumstances.1 passage
• Cardiovascular complications and risk of death in sickle-cell disease.1 passage
• Cardiovascular disease risk prediction equations in 400 000 primary care patients in New Zealand: a derivation and validation study.1 passage
• Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study.1 passage
• Cardiovascular risk prediction in type 2 diabetes before and after widespread screening: a derivation and validation study.1 passage
• Cardiovascular, respiratory, and related disorders: key messages from Disease Control Priorities, 3rd edition.1 passage
• Cardioverter defibrillator implantation without induction of ventricular fibrillation: a single-blind, non-inferiority, randomised controlled trial (SIMPLE).1 passage
• Care of diabetes in children and adolescents: controversies, changes, and consensus.1 passage
• Care of surgical infections by Médecins Sans Frontières Operations Centre Brussels in 2008-14.1 passage
• Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study.1 passage
• Cariprazine versus risperidone monotherapy for treatment of predominant negative symptoms in patients with schizophrenia: a randomised, double-blind, controlled trial.1 passage
• Cataracts.1 passage
• Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.1 passage
• Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study.1 passage
• Causes of death up to 10 years after admissions to hospitals for self-inflicted, drug-related or alcohol-related, or violent injury during adolescence: a retrospective, nationwide, cohort study.1 passage
• Causes of international increases in older age life expectancy.1 passage
• Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study.1 passage
• Caustic ingestion.1 passage
• Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial.1 passage
• Ceftolozane-tazobactam compared with levofloxacin in the treatment of complicated urinary-tract infections, including pyelonephritis: a randomised, double-blind, phase 3 trial (ASPECT-cUTI).1 passage
• Cemiplimab monotherapy for first-line treatment of advanced non-small-cell lung cancer with PD-L1 of at least 50%: a multicentre, open-label, global, phase 3, randomised, controlled trial.1 passage
• Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial.1 passage
• Central venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial.1 passage
• Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study.1 passage
• Cervical cancer.1 passage
• Chagas disease.1 passage
• Challenges and controversies in childhood tuberculosis.1 passage
• Challenges for immigrant health in the USA-the road to crisis.1 passage
• Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment.1 passage
• Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.1 passage
• Changes in cause-specific neonatal and 1-59-month child mortality in India from 2000 to 2015: a nationally representative survey.1 passage
• Changes in conceptions in women younger than 18 years and the circumstances of young mothers in England in 2000-12: an observational study.1 passage
• Changes in health in England, with analysis by English regions and areas of deprivation, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Changes in health in the countries of the UK and 150 English Local Authority areas 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Changing global policy to deliver safe, equitable, and affordable care for women's cancers.1 passage
• Changing the landscape for type 1 diabetes: the first step to prevention.1 passage
• Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study.1 passage
• Characteristics of immunosuppressive regulatory T cells in cutaneous squamous cell carcinomas and role in metastasis.1 passage
• Child and adolescent obesity: part of a bigger picture.1 passage
• Child deprivation among Palestinian refugees in Lebanon and Palestinian refugees from Syria living in Lebanon: a cross-sectional analysis of co-occurrence of deprivation indicators.1 passage
• Child mortality in England compared with Sweden: a birth cohort study.1 passage
• Child-to-adult neurodevelopmental and mental health trajectories after early life deprivation: the young adult follow-up of the longitudinal English and Romanian Adoptees study.1 passage
• China's Silk Road and global health.1 passage
• Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial.1 passage
• Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial.1 passage
• Choice of a patient-reported outcome measure for patients with anal cancer for use in cancer clinical trials and routine clinical practice: a mixed methods approach.1 passage
• Cholera.1 passage
• Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial.1 passage
• Chronic Kidney Disease.1 passage
• Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial.1 passage
• Chronic hepatitis B virus infection.1 passage
• Chronic kidney disease.1 passage
• Chronic lymphocytic leukaemia.1 passage
• Chronic myeloid leukaemia.2 passages
• Chronic obstructive pulmonary disease.1 passage
• Chronic pain: an update on burden, best practices, and new advances.1 passage
• Chronic pancreatitis.2 passages
• Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study.1 passage
• Circulating plasma microRNAs as a screening method for detection of colorectal adenomas.1 passage
• City planning and population health: a global challenge.1 passage
• Civil registration and vital statistics: progress in the data revolution for counting and accountability.1 passage
• Classical Hodgkin lymphoma.1 passage
• Classification, assessment, prevalence, and effect of personality disorder.1 passage
• Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.1 passage
• Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.1 passage
• Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study.1 passage
• Clinical and pathological characteristics and hormone receptor status of women with breast cancer in the European Gaza Hospital: a retrospective chart-based review.1 passage
• Clinical audit as a quality improvement tool in the Gaza Strip: an audit of audits.1 passage
• Clinical care of incarcerated people with HIV, viral hepatitis, or tuberculosis.1 passage
• Clinical challenges in mechanical ventilation.1 passage
• Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records.1 passage
• Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.1 passage
• Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial.1 passage
• Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial.1 passage
• Clinical evidence for oral antiplatelet therapy in acute coronary syndromes.1 passage
• Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.1 passage
• Clinical follow-up compared with self-assessment of outcome after medical abortion: a multicentre, non-inferiority, randomised, controlled trial.1 passage
• Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.1 passage
• Clinical management of psoriatic arthritis.1 passage
• Clinical outcomes after ABO-incompatible renal transplantation: a systematic review and meta-analysis.1 passage
• Clinical outcomes in patients with ST-segment elevation myocardial infarction treated with everolimus-eluting stents versus bare-metal stents (EXAMINATION): 5-year results of a randomised trial.1 passage
• Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.1 passage
• Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial.1 passage
• Clinical presentation, treatment, and short-term outcomes of lung injury associated with e-cigarettes or vaping: a prospective observational cohort study.1 passage
• Clinical remission in patients with moderate-to-severe Crohn's disease treated with filgotinib (the FITZROY study): results from a phase 2, double-blind, randomised, placebo-controlled trial.1 passage
• Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.1 passage
• Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in England, 2007-14.1 passage
• Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial.1 passage
• Clonorchiasis.1 passage
• Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome (POPular AGE): the randomised, open-label, non-inferiority trial.1 passage
• Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial.1 passage
• Closure of mesenteric defects in laparoscopic gastric bypass: a multicentre, randomised, parallel, open-label trial.1 passage
• Coeliac disease.1 passage
• Coformulated bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir with emtricitabine and tenofovir alafenamide, for initial treatment of HIV-1 infection (GS-US-380-1490): a randomised, double-blind, multicentre, phase 3, non-inferiority trial.1 passage
• Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study.1 passage
• Colorectal cancer.1 passage
• Combination HIV prevention for female sex workers: what is the evidence?1 passage
• Coming of age: health-care challenges of an ageing population in Israel.1 passage
• Communication with children and adolescents about the diagnosis of a life-threatening condition in their parent.1 passage
• Communication with children and adolescents about the diagnosis of their own life-threatening condition.1 passage
• Community health workers and smartphones for the detection of surgical site infections in rural Haiti: a pilot study.1 passage
• Community-acquired bacterial meningitis.1 passage
• Community-acquired pneumonia.2 passages
• Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis.1 passage
• Comparative effectiveness and safety of image guidance systems in surgery: a preclinical randomised study.1 passage
• Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X:BOT): a multicentre, open-label, randomised controlled trial.1 passage
• Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis.1 passage
• Comparative efficacy and safety of blood pressure-lowering agents in adults with diabetes and kidney disease: a network meta-analysis.1 passage
• Comparative efficacy and safety of reperfusion therapy with fibrinolytic agents in patients with ST-segment elevation myocardial infarction: a systematic review and network meta-analysis.1 passage
• Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis.1 passage
• Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.1 passage
• Comparing real-time and intermittently scanned continuous glucose monitoring in adults with type 1 diabetes (ALERTT1): a 6-month, prospective, multicentre, randomised controlled trial.1 passage
• Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial.1 passage
• Comparison of an everolimus-eluting bioresorbable scaffold with an everolimus-eluting metallic stent for the treatment of coronary artery stenosis (ABSORB II): a 3 year, randomised, controlled, single-blind, multicentre clinical trial.1 passage
• Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials.1 passage
• Comparison of stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease (eTHoS): a pragmatic, multicentre, randomised controlled trial.1 passage
• Comparison of treatment of incomplete abortion with misoprostol by physicians and midwives at district level in Uganda: a randomised controlled equivalence trial.1 passage
• Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial.1 passage
• Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study.1 passage
• Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial.1 passage
• Compliance with legal requirement to report clinical trial results on ClinicalTrials.gov: a cohort study.1 passage
• Complicated pneumonia in children.1 passage
• Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis.1 passage
• Comprehensive geriatric care for patients with hip fractures: a prospective, randomised, controlled trial.1 passage
• Computerised interpretation of fetal heart rate during labour (INFANT): a randomised controlled trial.1 passage
• Concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial.1 passage
• Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation.1 passage
• Congenital adrenal hyperplasia.1 passage
• Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines).1 passage
• Consolidating the social health insurance schemes in China: towards an equitable and efficient health system.1 passage
• Contemporary radiotherapy: present and future.1 passage
• Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial.1 passage
• Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial.1 passage
• Contraceptive use by Palestine refugee mothers of young children attending UNRWA clinics: a cross-sectional follow-up study.1 passage
• Contrasting male and female trends in tobacco-attributed mortality in China: evidence from successive nationwide prospective cohort studies.1 passage
• Contribution of non-HLA incompatibility between donor and recipient to kidney allograft survival: genome-wide analysis in a prospective cohort.1 passage
• Control of malaria vectors and management of insecticide resistance through universal coverage with next-generation insecticide-treated nets.1 passage
• Controlling the seedbeds of tuberculosis: diagnosis and treatment of tuberculosis infection.1 passage
• Controversies and problems of volume control and hypertension in haemodialysis.1 passage
• Controversies in faith and health care.1 passage
• Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.1 passage
• Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China.1 passage
• Coronary atherosclerosis in indigenous South American Tsimane: a cross-sectional cohort study.1 passage
• Coronary balloon angioplasty, stents, and scaffolds.1 passage
• Corruption in global health: the open secret.1 passage
• Cost and Outcome of Behavioural Activation versus Cognitive Behavioural Therapy for Depression (COBRA): a randomised, controlled, non-inferiority trial.1 passage
• Cost of surgery and catastrophic expenditure in people admitted to hospital for injuries: estimates from a cohort study in Vietnam.1 passage
• Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities, 3rd edition.1 passage
• Counselling for Alcohol Problems (CAP), a lay counsellor-delivered brief psychological treatment for harmful drinking in men, in primary care in India: a randomised controlled trial.1 passage
• Countdown to 2015 and beyond: fulfilling the health agenda for women and children.1 passage
• Countdown to 2015: a decade of tracking progress for maternal, newborn, and child survival.1 passage
• Countdown to 2030: tracking progress towards universal coverage for reproductive, maternal, newborn, and child health.1 passage
• Crohn's disease management after intestinal resection: a randomised trial.1 passage
• Crohn's disease.1 passage
• Cryptococcal meningitis screening and community-based early adherence support in people with advanced HIV infection starting antiretroviral therapy in Tanzania and Zambia: an open-label, randomised controlled trial.1 passage
• Current and future status of JAK inhibitors.1 passage
• Current approach of the axilla in patients with early-stage breast cancer.1 passage
• Current concepts in management of pain in children in the emergency department.1 passage
• Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management.1 passage
• Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke.1 passage
• Cushing's syndrome.1 passage
• Cyclin-dependent kinase 4 and 6 inhibitors for hormone receptor-positive breast cancer: past, present, and future.1 passage
• Cystic fibrosis.2 passages
• Cytosponge-trefoil factor 3 versus usual care to identify Barrett's oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial.1 passage
• Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial.1 passage
• Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.1 passage
• Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial.1 passage
• Daily experiences and strategies for psychological survival during the 2014 assaults in Gaza: a retrospective analysis of chronological diaries.1 passage
• Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial.1 passage
• Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial.1 passage
• Data for action: collection and use of local data to end tuberculosis.1 passage
• Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study.1 passage
• Deaths from acute abdominal conditions and geographic access to surgical care in India: a nationally representative population-based spatial analysis.1 passage
• Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study.1 passage
• Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.1 passage
• Deep vein thrombosis and pulmonary embolism.1 passage
• Deferred versus conventional stent implantation in patients with ST-segment elevation myocardial infarction (DANAMI 3-DEFER): an open-label, randomised controlled trial.1 passage
• Delay to admission to critical care and mortality among deteriorating ward patients in UK hospitals: a multicentre, prospective, observational cohort study.1 passage
• Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials.1 passage
• Delivering health and nutrition interventions for women and children in different conflict contexts: a framework for decision making on what, when, and how.1 passage
• Delivering health interventions to women, children, and adolescents in conflict settings: what have we learned from ten country case studies?1 passage
• Delivering modern, high-quality, affordable pathology and laboratory medicine to low-income and middle-income countries: a call to action.1 passage
• Delivering safe and effective analgesia for management of renal colic in the emergency department: a double-blind, multigroup, randomised controlled trial.1 passage
• Delivering trauma training to multiple health-worker cadres in nine sub-Saharan African countries: lessons learnt from the COOL programme.1 passage
• Demographics of patients affected by surgical disease in rural hospitals in two sub-Saharan African countries: a retrospective analysis.1 passage
• Dengue.2 passages
• Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial.1 passage
• Depression and post-traumatic stress during major social unrest in Hong Kong: a 10-year prospective cohort study.1 passage
• Depression in patients treated with haemodialysis: a cross-sectional study.1 passage
• Depression.1 passage
• Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score: a pooled analysis of individual-patient datasets from clinical trials.1 passage
• Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study.1 passage
• Development assistance for health: past trends, associations, and the future of international financial flows for health.1 passage
• Development of a targeted client communication intervention for pregnant and post-partum women: a descriptive study.1 passage
• Dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy (QUARTZ): results from a phase 3, non-inferiority, randomised trial.1 passage
• Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial.1 passage
• Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial.1 passage
• Diagnosis and treatment of acute extremity compartment syndrome.1 passage
• Diagnosis and treatment of tricuspid valve disease: current and future perspectives.1 passage
• Diagnosis of multiple sclerosis: progress and challenges.1 passage
• Diagnosis of non-consensus transient ischaemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis.1 passage
• Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study.1 passage
• Diagnostic accuracy of post-mortem CT with targeted coronary angiography versus autopsy for coroner-requested post-mortem investigations: a prospective, masked, comparison study.1 passage
• Diagnostic preparedness for infectious disease outbreaks.1 passage
• Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis.1 passage
• Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).1 passage
• Dilated cardiomyopathy.1 passage
• Direct oral anticoagulants: evidence and unresolved issues.1 passage
• Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial.1 passage
• Disease burden and costs from excess alcohol consumption, obesity, and viral hepatitis: fourth report of the Lancet Standing Commission on Liver Disease in the UK.1 passage
• Disease pathology in fibrotic interstitial lung disease: is it all about usual interstitial pneumonia?1 passage
• Disrupting gender norms in health systems: making the case for change.1 passage
• Dissonant health transition in the states of Mexico, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Diversity and divergence: the dynamic burden of poor maternal health.1 passage
• Does happiness itself directly affect mortality? The prospective UK Million Women Study.1 passage
• Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women.1 passage
• Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials.1 passage
• Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study.1 passage
• Double-duty actions: seizing programme and policy opportunities to address malnutrition in all its forms.1 passage
• Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial.1 passage
• Dressings and securements for the prevention of peripheral intravenous catheter failure in adults (SAVE): a pragmatic, randomised controlled, superiority trial.1 passage
• Drivers of maternity care in high-income countries: can health systems support woman-centred care?1 passage
• Drivers of poor medical care.1 passage
• Drug dosing errors in outpatient paediatric patients at primary health-care centres in Nablus: a cross-sectional study.1 passage
• Drug-coated balloon for treatment of de-novo coronary artery lesions in patients with high bleeding risk (DEBUT): a single-blind, randomised, non-inferiority trial.1 passage
• Drug-coated balloons for small coronary artery disease (BASKET-SMALL 2): an open-label randomised non-inferiority trial.1 passage
• Drug-eluting or bare-metal stents for percutaneous coronary intervention: a systematic review and individual patient data meta-analysis of randomised clinical trials.1 passage
• Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial.1 passage
• Drug-eluting stents versus bare-metal stents in saphenous vein grafts: a double-blind, randomised trial.1 passage
• Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial.1 passage
• Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial.1 passage
• Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial.1 passage
• Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial.1 passage
• Dynamic contrast-enhanced MRI to predict response to vinorelbine-cisplatin alone or with rh-endostatin in patients with non-small cell lung cancer and bone metastases: a randomised, double-blind, placebo-controlled trial.1 passage
• Dynamics of the double burden of malnutrition and the changing nutrition reality.1 passage
• Dysfunction of NaV1.4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study.1 passage
• Early childhood development coming of age: science through the life course.1 passage
• Early chronic obstructive pulmonary disease: definition, assessment, and prevention.1 passage
• Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial.1 passage
• Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial.1 passage
• Early invasive versus non-invasive treatment in patients with non-ST-elevation acute coronary syndrome (FRISC-II): 15 year follow-up of a prospective, randomised, multicentre study.1 passage
• Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial.1 passage
• Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial.1 passage
• Eating disorders.1 passage
• Ebola virus disease.1 passage
• Economic downturns, universal health coverage, and cancer mortality in high-income and middle-income countries, 1990-2010: a longitudinal analysis.1 passage
• Economic effects of the double burden of malnutrition.1 passage
• Edoxaban versus enoxaparin-warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial.1 passage
• Edoxaban-based versus vitamin K antagonist-based antithrombotic regimen after successful coronary stenting in patients with atrial fibrillation (ENTRUST-AF PCI): a randomised, open-label, phase 3b trial.1 passage
• Educating religious leaders to promote uptake of male circumcision in Tanzania: a cluster randomised trial.1 passage
• Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: the African Investigation of the Mirasol System (AIMS) randomised controlled trial.1 passage
• Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus.1 passage
• Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study.1 passage
• Effect of anandamide on endometrial adenocarcinoma (Ishikawa) cell numbers: implications for endometrial cancer therapy.1 passage
• Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial.1 passage
• Effect of collaborative care between traditional and faith healers and primary health-care workers on psychosis outcomes in Nigeria and Ghana (COSIMPO): a cluster randomised controlled trial.1 passage
• Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial.1 passage
• Effect of early low-dose hydrocortisone on survival without bronchopulmonary dysplasia in extremely preterm infants (PREMILOC): a double-blind, placebo-controlled, multicentre, randomised trial.1 passage
• Effect of early neonatal vitamin A supplementation on mortality during infancy in Ghana (Neovita): a randomised, double-blind, placebo-controlled trial.1 passage
• Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial.1 passage
• Effect of fluticasone propionate on virus-induced airways inflammation and anti-viral immune responses in mice.1 passage
• Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme.1 passage
• Effect of hypertension on pregnancy outcomes at UNRWA health centres in Gaza governorates: a comparative study.1 passage
• Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.1 passage
• Effect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (central venous access device)-non-inferiority (peripheral arterial catheter) trial.1 passage
• Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial.1 passage
• Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): a pragmatic, cluster-randomised trial embedded in a national LLIN distribution campaign.1 passage
• Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial.1 passage
• Effect of methotrexate on JAK/STAT pathway activation in myeloproliferative neoplasms.1 passage
• Effect of neonatal vitamin A supplementation on mortality in infants in Tanzania (Neovita): a randomised, double-blind, placebo-controlled trial.1 passage
• Effect of nurse-supported care on pain management in women undergoing caesarean delivery: a comparative study.1 passage
• Effect of platelet-rich plasma on healing tissues in acute ruptured Achilles tendon: a human immunohistochemistry study.1 passage
• Effect of regional versus local anaesthesia on outcome after arteriovenous fistula creation: a randomised controlled trial.1 passage
• Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.1 passage
• Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial.1 passage
• Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial.1 passage
• Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study.1 passage
• Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial.1 passage
• Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial.1 passage
• Effect of tight control of inflammation in early psoriatic arthritis (TICOPA): a UK multicentre, open-label, randomised controlled trial.1 passage
• Effect of tissue inhibitor of metalloproteinases 3 on DLK1 shedding in cultured human pre-adipocytes and implications for adipose tissue remodelling.1 passage
• Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients.1 passage
• Effect of ultra-short-term treatment of patients with iron deficiency or anaemia undergoing cardiac surgery: a prospective randomised trial.1 passage
• Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial.1 passage
• Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial.1 passage
• Effectiveness and cost-effectiveness of reactive, targeted indoor residual spraying for malaria control in low-transmission settings: a cluster-randomised, non-inferiority trial in South Africa.1 passage
• Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: a national observational cohort study.1 passage
• Effectiveness and sustainability of a diagonal investment approach to strengthen the primary health-care system in Ethiopia.1 passage
• Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial.1 passage
• Effectiveness of a brief group psychological intervention for women in a post-conflict setting in Pakistan: a single-blind, cluster, randomised controlled trial.1 passage
• Effectiveness of a group B outer membrane vesicle meningococcal vaccine against gonorrhoea in New Zealand: a retrospective case-control study.1 passage
• Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial.1 passage
• Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial.1 passage
• Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial.1 passage
• Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study.1 passage
• Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial.1 passage
• Effectiveness of fluticasone furoate plus vilanterol on asthma control in clinical practice: an open-label, parallel group, randomised controlled trial.1 passage
• Effectiveness of household lockable pesticide storage to reduce pesticide self-poisoning in rural Asia: a community-based, cluster-randomised controlled trial.1 passage
• Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study.1 passage
• Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis.1 passage
• Effectiveness of personalised risk information and taster sessions to increase the uptake of smoking cessation services (Start2quit): a randomised controlled trial.1 passage
• Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.1 passage
• Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial.1 passage
• Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study.1 passage
• Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.1 passage
• Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.1 passage
• Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study.1 passage
• Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial.1 passage
• Effects of aspirin on risk and severity of early recurrent stroke after transient ischaemic attack and ischaemic stroke: time-course analysis of randomised trials.1 passage
• Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials.1 passage
• Effects of blood pressure lowering on cardiovascular risk according to baseline body-mass index: a meta-analysis of randomised trials.1 passage
• Effects of change in hospital treatment payment policy for Palestinian refugees in Lebanon: a health economics analysis.1 passage
• Effects of decreases of animal pollinators on human nutrition and global health: a modelling analysis.1 passage
• Effects of evidence-based strategies to reduce the socioeconomic gradient of uptake in the English NHS Bowel Cancer Screening Programme (ASCEND): four cluster-randomised controlled trials.1 passage
• Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial.1 passage
• Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis.1 passage
• Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions, and length of stay: a prospective study in a panel of hospitals.1 passage
• Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial.1 passage
• Effects of the Informed Health Choices podcast on the ability of parents of primary school children in Uganda to assess claims about treatment effects: a randomised controlled trial.1 passage
• Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial.1 passage
• Effects of the Learning Together intervention on bullying and aggression in English secondary schools (INCLUSIVE): a cluster randomised controlled trial.1 passage
• Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.1 passage
• Effects, equity, and cost of school-based and community-wide treatment strategies for soil-transmitted helminths in Kenya: a cluster-randomised controlled trial.1 passage
• Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial.1 passage
• Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.1 passage
• Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!).1 passage
• Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial.1 passage
• Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial.1 passage
• Efficacy and safety of 12 weeks versus 18 weeks of treatment with grazoprevir (MK-5172) and elbasvir (MK-8742) with or without ribavirin for hepatitis C virus genotype 1 infection in previously untreated patients with cirrhosis and patients with previous null response with or without cirrhosis (C-WORTHY): a randomised, open-label phase 2 trial.1 passage
• Efficacy and safety of 8 weeks versus 12 weeks of treatment with grazoprevir (MK-5172) and elbasvir (MK-8742) with or without ribavirin in patients with hepatitis C virus genotype 1 mono-infection and HIV/hepatitis C virus co-infection (C-WORTHY): a randomised, open-label phase 2 trial.1 passage
• Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials.1 passage
• Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial.1 passage
• Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial.1 passage
• Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial.1 passage
• Efficacy and safety of abrocitinib in adults and adolescents with moderate-to-severe atopic dermatitis (JADE MONO-1): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial.1 passage
• Efficacy and safety of adalimumab every other week versus methotrexate once weekly in children and adolescents with severe chronic plaque psoriasis: a randomised, double-blind, phase 3 trial.1 passage
• Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey.1 passage
• Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β1 passage
• Efficacy and safety of biosimilar CT-P13 compared with originator infliximab in patients with active Crohn's disease: an international, randomised, double-blind, phase 3 non-inferiority study.1 passage
• Efficacy and safety of continuing versus withdrawing adalimumab therapy in maintaining remission in patients with non-radiographic axial spondyloarthritis (ABILITY-3): a multicentre, randomised, double-blind study.1 passage
• Efficacy and safety of cyclic pyranopterin monophosphate substitution in severe molybdenum cofactor deficiency type A: a prospective cohort study.1 passage
• Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial.1 passage
• Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial.1 passage
• Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.1 passage
• Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active ankylosing spondylitis (TORTUGA): results from a randomised, placebo-controlled, phase 2 trial.1 passage
• Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active psoriatic arthritis (EQUATOR): results from a randomised, placebo-controlled, phase 2 trial.1 passage
• Efficacy and safety of guselkumab in patients with active psoriatic arthritis: a randomised, double-blind, placebo-controlled, phase 2 study.1 passage
• Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials.1 passage
• Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study.1 passage
• Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial.1 passage
• Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.1 passage
• Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial.1 passage
• Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials.1 passage
• Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial.1 passage
• Efficacy and safety of sirukumab in patients with active rheumatoid arthritis refractory to anti-TNF therapy (SIRROUND-T): a randomised, double-blind, placebo-controlled, parallel-group, multinational, phase 3 study.1 passage
• Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials.1 passage
• Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.1 passage
• Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.1 passage
• Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial.1 passage
• Efficacy and safety of trimetazidine after percutaneous coronary intervention (ATPCI): a randomised, double-blind, placebo-controlled trial.1 passage
• Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial.1 passage
• Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study.1 passage
• Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial.1 passage
• Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.1 passage
• Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial.1 passage
• Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous preventive treatments were unsuccessful: a randomised, double-blind, placebo-controlled, phase 3b study.1 passage
• Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial.1 passage
• Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial.1 passage
• Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.1 passage
• Efficacy of a tetravalent dengue vaccine in healthy children aged 4-16 years: a randomised, placebo-controlled, phase 3 trial.1 passage
• Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial.1 passage
• Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovita): a randomised, double-blind, placebo-controlled trial.1 passage
• Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial.1 passage
• Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets: a cluster-randomised controlled trial.1 passage
• Efficacy of infant simulator programmes to prevent teenage pregnancy: a school-based cluster randomised controlled trial in Western Australia.1 passage
• Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.1 passage
• Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial.1 passage
• Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased risk of non-response to intravenous immunoglobulin (KAICA): a randomised controlled, open-label, blinded-endpoints, phase 3 trial.1 passage
• Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.1 passage
• Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial.1 passage
• Efficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18-64 years) and older adults (≥65 years): two multicentre, randomised phase 3 trials.1 passage
• Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Efficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a randomised, double-blind, controlled, phase 3 trial.1 passage
• Efficacy, safety, and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in late life: a randomised, double-blind, placebo-controlled trial.1 passage
• Efficacy, safety, and tolerability of dolutegravir-rilpivirine for the maintenance of virological suppression in adults with HIV-1: phase 3, randomised, non-inferiority SWORD-1 and SWORD-2 studies.1 passage
• Efficacy, safety, and tolerability of rimegepant orally disintegrating tablet for the acute treatment of migraine: a randomised, phase 3, double-blind, placebo-controlled trial.1 passage
• Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pulmonary tuberculosis.1 passage
• Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors.1 passage
• Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial.1 passage
• Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibrillation (RAFF2): a partial factorial randomised trial.1 passage
• Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70-100 years: a contemporary primary prevention cohort.1 passage
• Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study.1 passage
• Eliglustat compared with imiglucerase in patients with Gaucher's disease type 1 stabilised on enzyme replacement therapy: a phase 3, randomised, open-label, non-inferiority trial.1 passage
• Eliminating postnatal HIV transmission in high incidence areas: need for complementary biomedical interventions.1 passage
• Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): a randomised, multicentre, placebo-controlled trial.1 passage
• Emergency department attendance by patients with cancer in the last month of life: a systematic review and meta-analysis.1 passage
• Emergency response of the UNRWA health programme to Great March of Return injuries: a descriptive analytic study in Gaza.1 passage
• Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial.1 passage
• Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.1 passage
• Ending the neglect of global oral health: time for radical action.1 passage
• Endometrial cancer.1 passage
• Endometriosis is a chronic systemic disease: clinical challenges and novel innovations.1 passage
• Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial.1 passage
• Endovascular baroreflex amplification for resistant hypertension: a safety and proof-of-principle clinical study.1 passage
• Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.1 passage
• Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial.1 passage
• Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial.1 passage
• Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study.1 passage
• Enhancing anti-tumour efficacy with immunotherapy combinations.1 passage
• Enhancing the quality of maternal and neonatal care by the Safe Childbirth Project in Al Shifa Hospital, Gaza occupied Palestinian territory (oPt): a descriptive retrospective study.1 passage
• Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial.1 passage
• Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2).1 passage
• Environmental pollution, health, and development: a Lancet-Global Alliance on Health and Pollution-Icahn School of Medicine at Mount Sinai Commission.1 passage
• Environmental risk factors for type 1 diabetes.1 passage
• Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study.1 passage
• Epidemiology and outcomes of older patients admitted to Scottish intensive care units: a national database linkage study.1 passage
• Epidemiology of HIV in the USA: epidemic burden, inequities, contexts, and responses.1 passage
• Epidemiology of untreated non-obstetric surgical disease in Burera District, Rwanda: a cross-sectional survey.1 passage
• Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study.1 passage
• Epilepsy in adults.1 passage
• Epilepsy in older people.1 passage
• Epilepsy in pregnancy and reproductive outcomes: a systematic review and meta-analysis.1 passage
• Epilepsy: new advances.1 passage
• Epithelial ovarian cancer.1 passage
• Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial.1 passage
• Equity impacts of price policies to promote healthy behaviours.1 passage
• Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.1 passage
• Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.1 passage
• Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial.1 passage
• Essential surgery: key messages from Disease Control Priorities, 3rd edition.1 passage
• Establishment of a urology service in a developing country: an observational study of outcomes in transurethral prostate resection procedures in Vanuatu.1 passage
• Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes.1 passage
• Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015.1 passage
• Estimates of global seasonal influenza-associated respiratory mortality: a modelling study.1 passage
• Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study.1 passage
• Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study.1 passage
• Estimating lifetime benefits of comprehensive disease-modifying pharmacological therapies in patients with heart failure with reduced ejection fraction: a comparative analysis of three randomised controlled trials.1 passage
• Estimating the cause-specific relative risks of non-optimal temperature on daily mortality: a two-part modelling approach applied to the Global Burden of Disease Study.1 passage
• Estimating the early impact of the US COVID-19 vaccination programme on COVID-19 cases, emergency department visits, hospital admissions, and deaths among adults aged 65 years and older: an ecological analysis of national surveillance data.1 passage
• Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study.1 passage
• Estimating total spending by source of funding on routine and supplementary immunisation activities in low-income and middle-income countries, 2000-17: a financial modelling study.1 passage
• Estimation of the economic burden of injury in north India: a prospective cohort study.1 passage
• Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.1 passage
• Ethical issues in dialysis therapy.1 passage
• Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform.1 passage
• Evaluating Progestogens for Preventing Preterm birth International Collaborative (EPPPIC): meta-analysis of individual participant data from randomised controlled trials.1 passage
• Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19).1 passage
• Evaluation of carotid plaque inflammation in patients with active rheumatoid arthritis using (18)F-fluorodeoxyglucose PET-CT and MRI: a pilot study.1 passage
• Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study.1 passage
• Evaluation of the role of miR-31-dependent reduction in dystrophin and nNOS on atrial-fibrillation-induced electrical remodelling in man.1 passage
• Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study.1 passage
• Everolimus-eluting bioresorbable vascular scaffolds versus everolimus-eluting metallic stents: a meta-analysis of randomised controlled trials.1 passage
• Evidence for effective interventions to reduce mental-health-related stigma and discrimination.1 passage
• Evidence for overuse of medical services around the world.1 passage
• Evidence for underuse of effective medical services around the world.1 passage
• Evidence on public health interventions in humanitarian crises.1 passage
• Evidence-based guidelines for supportive care of patients with Ebola virus disease.1 passage
• Evolution, human-microbe interactions, and life history plasticity.1 passage
• Evolutionary public health: introducing the concept.1 passage
• Evolving concepts in the treatment of relapsing multiple sclerosis.1 passage
• Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial.1 passage
• Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study.1 passage
• Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.1 passage
• Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial.1 passage
• Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial.1 passage
• Expanding traditional tendon-based techniques with nerve transfers for the restoration of upper limb function in tetraplegia: a prospective case series.1 passage
• Expansion of laparoscopic cholecystectomy in a resource limited setting, Mongolia: a 9-year cross-sectional retrospective review.1 passage
• Exploring the evidence base for national and regional policy interventions to combat resistance.1 passage
• Exposing and addressing tobacco industry conduct in low-income and middle-income countries.1 passage
• Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial.1 passage
• Extended duration dual antiplatelet therapy and mortality: a systematic review and meta-analysis.1 passage
• Extended pre-exposure prophylaxis with lopinavir-ritonavir versus lamivudine to prevent HIV-1 transmission through breastfeeding up to 50 weeks in infants in Africa (ANRS 12174): a randomised controlled trial.1 passage
• Extending thrombolysis to 4·5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data.1 passage
• External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial.1 passage
• Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry.1 passage
• Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry.1 passage
• Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial.1 passage
• Extreme, expedition, and wilderness medicine.1 passage
• Face transplant: long-term follow-up and results of a prospective open study.1 passage
• Factors affecting adherence to appointment system in the clinic for non-communicable diseases in UNRWA's Khan Younis Health Centre and the role of mobile phone text messages to improve adherence: a descriptive cross-sectional study.1 passage
• Factors affecting outcomes in patients reaching end-stage kidney disease worldwide: differences in access to renal replacement therapy, modality use, and haemodialysis practices.1 passage
• Factors affecting sex-related reporting in medical research: a cross-disciplinary bibliometric analysis.1 passage
• Factors associated with depression in patients with type 2 diabetes in the Gaza Strip: a cross sectional study.1 passage
• Factors associated with early provision of respiratory support in deteriorating ward patients with chest sepsis.1 passage
• Factors related to high dental caries experience in Palestinian pregnant women in the Jerusalem governorate: a cross-sectional study.1 passage
• Fall rates in hospital rehabilitation units after individualised patient and staff education programmes: a pragmatic, stepped-wedge, cluster-randomised controlled trial.1 passage
• Family health history: underused for actionable risk assessment.1 passage
• Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial.1 passage
• Fangcang shelter hospitals: a novel concept for responding to public health emergencies.1 passage
• Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial.1 passage
• Fatal police violence by race and state in the USA, 1980-2019: a network meta-regression.1 passage
• Feasibility and effectiveness of oral cholera vaccine in an urban endemic setting in Bangladesh: a cluster randomised open-label trial.1 passage
• Feasibility of alcohol misuse screening and treatment in the dental setting.1 passage
• Femtosecond laser-assisted versus phacoemulsification cataract surgery (FEMCAT): a multicentre participant-masked randomised superiority and cost-effectiveness trial.1 passage
• Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial.1 passage
• Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial.1 passage
• Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: a forecasting analysis for the Global Burden of Disease Study.1 passage
• Fetal haemoglobin in sickle-cell disease: from genetic epidemiology to new therapeutic strategies.1 passage
• Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial.1 passage
• Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16-26 years: a randomised, double-blind trial.1 passage
• Financial contribution to global surgery: an analysis of 160 international charitable organisations.1 passage
• Financing universal health coverage--effects of alternative tax structures on public health systems: cross-national modelling in 89 low-income and middle-income countries.1 passage
• Firearm legislation and firearm mortality in the USA: a cross-sectional, state-level study.1 passage
• First clinical use of a bioprosthetic total artificial heart: report of two cases.1 passage
• First human facial retransplantation: 30-month follow-up.1 passage
• First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA.1 passage
• First-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial.1 passage
• First-line ceritinib versus platinum-based chemotherapy in advanced ALK-rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study.1 passage
• First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial.1 passage
• First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial.1 passage
• First-line rituximab combined with short-term prednisone versus prednisone alone for the treatment of pemphigus (Ritux 3): a prospective, multicentre, parallel-group, open-label randomised trial.1 passage
• First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment.1 passage
• Five insights from the Global Burden of Disease Study 2019.1 passage
• Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis.1 passage
• Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial.1 passage
• Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial.1 passage
• Foley catheterisation versus oral misoprostol for induction of labour in hypertensive women in India (INFORM): a multicentre, open-label, randomised controlled trial.1 passage
• Food choice in transition: adolescent autonomy, agency, and the food environment.1 passage
• Food insecurity in the context of conflict: analysis of survey data in the occupied Palestinian territory.1 passage
• Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016-40 for 195 countries and territories.1 passage
• Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial.1 passage
• Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.1 passage
• Fractional dosing of yellow fever vaccine to extend supply: a modelling study.1 passage
• Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial.1 passage
• Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial.1 passage
• Fragmented health systems in COVID-19: rectifying the misalignment between global health security and universal health coverage.1 passage
• Frailty: implications for clinical practice and public health.1 passage
• Fremanezumab versus placebo for migraine prevention in patients with documented failure to up to four migraine preventive medication classes (FOCUS): a randomised, double-blind, placebo-controlled, phase 3b trial.1 passage
• From work with men and boys to changes of social norms and reduction of inequities in gender relations: a conceptual shift in prevention of violence against women and girls.1 passage
• Frontotemporal dementia.1 passage
• Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial.1 passage
• Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study.1 passage
• Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 trial.1 passage
• Functional dyspepsia.1 passage
• Functional gastrointestinal disorders: advances in understanding and management.1 passage
• Funding flows to global surgery: an analysis of contributions from the USA.1 passage
• Future and potential spending on health 2015-40: development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries.1 passage
• Future life expectancy in 35 industrialised countries: projections with a Bayesian model ensemble.1 passage
• Gabapentin for chronic pelvic pain in women (GaPP2): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Gastric cancer.2 passages
• Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial.1 passage
• Gathering momentum for the way ahead: fifth report of the Lancet Standing Commission on Liver Disease in the UK.1 passage
• Gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.1 passage
• Gender equality and gender norms: framing the opportunities for health.1 passage
• Gender equality in science, medicine, and global health: where are we at and why does it matter?1 passage
• Gender inequality and restrictive gender norms: framing the challenges to health.1 passage
• Gender norms and health: insights from global survey data.1 passage
• Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial.1 passage
• General surgery education: a systematic review of training worldwide.1 passage
• General versus spinal anaesthesia for caesarean section: a quasi-controlled trial.1 passage
• Generating comparative evidence on new drugs and devices after approval.1 passage
• Generating comparative evidence on new drugs and devices before approval.1 passage
• Generation of global political priority for early childhood development: the challenges of framing and governance.1 passage
• Generation of national political priority for surgery: a qualitative case study of three low-income and middle-income countries.1 passage
• Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data.1 passage
• Genetic risk factors for type 1 diabetes.1 passage
• Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.1 passage
• Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children.1 passage
• Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.1 passage
• Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.1 passage
• Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.1 passage
• Genome-wide transcription profiling in neutrophils in acute respiratory distress syndrome.1 passage
• Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.1 passage
• Genomic insights into the causes of type 2 diabetes.1 passage
• Genomic medicine for undiagnosed diseases.1 passage
• Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial.1 passage
• Geospatial mapping to estimate timely access to surgical care in nine low-income and middle-income countries.1 passage
• Germany's expanding role in global health.1 passage
• Gestational age recorded at delivery versus estimations using antenatal care data from the Electronic Maternal and Child Health Registry in the West Bank: a comparative analysis.1 passage
• Glaucoma.1 passage
• Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.1 passage
• Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study.1 passage
• Global and regional health effects of future food production under climate change: a modelling study.1 passage
• Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.1 passage
• Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.1 passage
• Global burden of HIV, viral hepatitis, and tuberculosis in prisoners and detainees.1 passage
• Global burden of diseases, injuries, and risk factors for young people's health during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Global epidemiology of HIV among female sex workers: influence of structural determinants.1 passage
• Global epidemiology of use of and disparities in caesarean sections.1 passage
• Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019.1 passage
• Global health burden and needs of transgender populations: a review.1 passage
• Global health security: the wider lessons from the west African Ebola virus disease epidemic.1 passage
• Global hearing health care: new findings and perspectives.1 passage
• Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy.1 passage
• Global minimum estimates of children affected by COVID-19-associated orphanhood and deaths of caregivers: a modelling study.1 passage
• Global patterns of mortality in international migrants: a systematic review and meta-analysis.1 passage
• Global patterns of opioid use and dependence: harms to populations, interventions, and future action.1 passage
• Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).1 passage
• Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic.1 passage
• Global surgical and anaesthetic task shifting: a systematic literature review and survey.1 passage
• Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2).1 passage
• Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.1 passage
• Global trends and projections for tobacco use, 1990-2025: an analysis of smoking indicators from the WHO Comprehensive Information Systems for Tobacco Control.1 passage
• Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries.1 passage
• Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.1 passage
• Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals.1 passage
• Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition.1 passage
• Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study.1 passage
• Global, regional, and national estimates and trends in stillbirths from 2000 to 2019: a systematic assessment.1 passage
• Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.1 passage
• Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Global, regional, and national levels and trends in maternal mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Maternal Mortality Estimation Inter-Agency Group.1 passage
• Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for Child Mortality Estimation.1 passage
• Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Global, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019.1 passage
• Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019.1 passage
• Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study.1 passage
• Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Global, regional, and subregional classification of abortions by safety, 2010-14: estimates from a Bayesian hierarchical model.1 passage
• Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.1 passage
• Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial.1 passage
• Gonadotrophins versus clomifene citrate with or without intrauterine insemination in women with normogonadotropic anovulation and clomifene failure (M-OVIN): a randomised, two-by-two factorial trial.1 passage
• Gout.2 passages
• Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4-5 chronic kidney disease (the C-SURFER study): a combination phase 3 study.1 passage
• Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial.1 passage
• Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial.1 passage
• Guided versus standard antiplatelet therapy in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis.1 passage
• Guidelines for Accurate and Transparent Health Estimates Reporting: the GATHER statement.1 passage
• Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.1 passage
• Guillain-Barré syndrome.2 passages
• Guselkumab in biologic-naive patients with active psoriatic arthritis (DISCOVER-2): a double-blind, randomised, placebo-controlled phase 3 trial.1 passage
• Guselkumab in patients with active psoriatic arthritis who were biologic-naive or had previously received TNFα inhibitor treatment (DISCOVER-1): a double-blind, randomised, placebo-controlled phase 3 trial.1 passage
• Guselkumab versus secukinumab for the treatment of moderate-to-severe psoriasis (ECLIPSE): results from a phase 3, randomised controlled trial.1 passage
• Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study.1 passage
• HER2-positive breast cancer.1 passage
• HIV and tuberculosis in prisons in sub-Saharan Africa.1 passage
• HIV and women in the USA: what we know and where to go from here.1 passage
• HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a randomised, multicentre, open-label trial.1 passage
• HIV risk and preventive interventions in transgender women sex workers.1 passage
• HIV, prisoners, and human rights.1 passage
• HIV.1 passage
• HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.1 passage
• Haemochromatosis.1 passage
• Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial.1 passage
• Haemolytic uraemic syndrome.1 passage
• Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial.1 passage
• Head and neck cancer in South Asia: macroeconomic consequences and the role of surgery.1 passage
• Head and neck cancer.1 passage
• Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study.1 passage
• Health and dignity of Palestine refugees at stake: a need for international response to sustain crucial life services at UNRWA.1 passage
• Health and wellbeing of Indigenous adolescents in Australia: a systematic synthesis of population data.1 passage
• Health attacks and protection strategies during Gaza's Great March of Return: a mixed methods study using data from WHO's Surveillance System for Attacks on Healthcare.1 passage
• Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Health effects of radiation and other health problems in the aftermath of nuclear accidents, with an emphasis on Fukushima.1 passage
• Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis.1 passage
• Health sector spending and spending on HIV/AIDS, tuberculosis, and malaria, and development assistance for health: progress towards Sustainable Development Goal 3.1 passage
• Health security capacities in the context of COVID-19 outbreak: an analysis of International Health Regulations annual report data from 182 countries.1 passage
• Health systems development in Thailand: a solid platform for successful implementation of universal health coverage.1 passage
• Health workers and the weaponisation of health care in Syria: a preliminary inquiry for The Lancet-American University of Beirut Commission on Syria.1 passage
• Health, functioning, and disability in older adults--present status and future implications.1 passage
• Health-system reform and universal health coverage in Latin America.1 passage
• Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015.1 passage
• Hearing loss prevalence and years lived with disability, 1990-2019: findings from the Global Burden of Disease Study 2019.1 passage
• Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial.1 passage
• Heart failure drug treatment.1 passage
• Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy.1 passage
• Heart failure.1 passage
• Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.1 passage
• Helicobacter pylori resistance to antibiotics at the An-Najah National University Hospital: a cross-sectional study.1 passage
• Hepatitis C.2 passages
• Hepatocellular carcinoma.1 passage
• High-flow oxygen therapy and other inhaled therapies in intensive care units.1 passage
• High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial.1 passage
• High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study.1 passage
• High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial.1 passage
• Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial.1 passage
• Hip replacement.1 passage
• Histiocytosis.1 passage
• Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series.1 passage
• Home modifications to reduce injuries from falls in the home injury prevention intervention (HIPI) study: a cluster-randomised controlled trial.1 passage
• Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial.1 passage
• Hot weather and heat extremes: health risks.1 passage
• How an outbreak became a pandemic: a chronological analysis of crucial junctures and international obligations in the early months of the COVID-19 pandemic.1 passage
• How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.1 passage
• How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.1 passage
• How much donor financing for health is channelled to global versus country-specific aid functions?1 passage
• How much surgery is enough? Aligning surgical delivery with best-performing health systems.1 passage
• How will Brexit affect health and health services in the UK? Evaluating three possible scenarios.1 passage
• How will Brexit affect health services in the UK? An updated evaluation.1 passage
• How women are treated during facility-based childbirth in four countries: a cross-sectional study with labour observations and community-based surveys.1 passage
• Human African trypanosomiasis.1 passage
• Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies.1 passage
• Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study.1 passage
• Human reproduction and health: an evolutionary perspective.1 passage
• Human rights and fair access to COVID-19 vaccines: the International AIDS Society-Lancet Commission on Health and Human Rights.1 passage
• Human rights violations against sex workers: burden and effect on HIV.1 passage
• Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two doses of inactivated poliovirus vaccine in Latin American infants: an open-label randomised controlled trial.1 passage
• Hydrocephalus in children.1 passage
• Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.1 passage
• Hyperparathyroidism.1 passage
• Hypertension.1 passage
• Hyperthyroidism.1 passage
• Hypertrophic cardiomyopathy: a practical approach to guideline directed management.1 passage
• Hypertrophic obstructive cardiomyopathy.1 passage
• Hypertrophic scarring: the greatest unmet challenge after burn injury.1 passage
• Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial.1 passage
• Hypopituitarism.1 passage
• Hypothyroidism.1 passage
• Hysteroscopy before in-vitro fertilisation (inSIGHT): a multicentre, randomised controlled trial.1 passage
• Hysteroscopy in recurrent in-vitro fertilisation failure (TROPHY): a multicentre, randomised controlled trial.1 passage
• IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial.1 passage
• IL17A/F nanobody sonelokimab in patients with plaque psoriasis: a multicentre, randomised, placebo-controlled, phase 2b study.1 passage
• Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study.1 passage
• Identification of novel biomarkers in plasma for prediction of treatment response in patients with heart failure.1 passage
• Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study.1 passage
• Identification of vulnerable plaques and patients by intracoronary near-infrared spectroscopy and ultrasound (PROSPECT II): a prospective natural history study.1 passage
• Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study.1 passage
• Idiopathic nephrotic syndrome in children.1 passage
• Idiopathic pulmonary fibrosis.1 passage
• IgG4-related disease.1 passage
• Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial.1 passage
• Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial.1 passage
• Immediate total-body CT scanning versus conventional imaging and selective CT scanning in patients with severe trauma (REACT-2): a randomised controlled trial.1 passage
• Immune checkpoint inhibitors in melanoma.1 passage
• Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial.1 passage
• Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial.1 passage
• Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial.1 passage
• Immunogenicity of a new routine vaccination schedule for global poliomyelitis prevention: an open-label, randomised controlled trial.1 passage
• Immunogenicity of full and fractional dose of inactivated poliovirus vaccine for use in routine immunisation and outbreak response: an open-label, randomised controlled trial.1 passage
• Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial.1 passage
• Immunogenicity, safety, and tolerability of the measles-vectored chikungunya virus vaccine MV-CHIK: a double-blind, randomised, placebo-controlled and active-controlled phase 2 trial.1 passage
• Impact and cost-effectiveness of a lethal house lure against malaria transmission in central Côte d'Ivoire: a two-arm, cluster-randomised controlled trial.1 passage
• Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data.1 passage
• Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries.1 passage
• Impact of air pollution on the burden of chronic respiratory diseases in China: time for urgent action.1 passage
• Impact of proposal to extend charging for NHS in England.1 passage
• Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.1 passage
• Implementation research: new imperatives and opportunities in global health.1 passage
• Importance of endogenous compensatory vasoactive peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure.1 passage
• Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial.1 passage
• Improving comfort around dying in elderly people: a cluster randomised controlled trial.1 passage
• Improving health with programmatic, legal, and policy approaches to reduce gender inequality and change restrictive gender norms.1 passage
• Improving lung health in low-income and middle-income countries: from challenges to solutions.1 passage
• Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions.1 passage
• Improving patient safety in Palestinian hospitals: a cross-sectional and retrospective chart review study.1 passage
• Improving the health and welfare of people who live in slums.1 passage
• Improving the prognosis of health care in the USA.1 passage
• In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix.1 passage
• Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Inappropriate opioid prescription after surgery.1 passage
• Incidence of infective endocarditis in England, 2000-13: a secular trend, interrupted time-series analysis.1 passage
• Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.1 passage
• Increasing value and reducing waste in biomedical research: who's listening?1 passage
• Indicators linking health and sustainability in the post-2015 development agenda.1 passage
• Indigenous and tribal peoples' health (The Lancet-Lowitja Institute Global Collaboration): a population study.1 passage
• Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial.1 passage
• Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial.1 passage
• Induction of labour at term with oral misoprostol versus a Foley catheter (PROBAAT-II): a multicentre randomised controlled non-inferiority trial.1 passage
• Induction of labour versus expectant management for large-for-date fetuses: a randomised controlled trial.1 passage
• Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study.1 passage
• Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.1 passage
• Inequalities in non-communicable diseases between the major population groups in Israel: achievements and challenges.1 passage
• Inequality and the health-care system in the USA.1 passage
• Infantile haemangioma.1 passage
• Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis.1 passage
• Infective endocarditis.1 passage
• Influenza.1 passage
• Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.1 passage
• Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.1 passage
• Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial.1 passage
• Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.1 passage
• Inpatient management of community-acquired pneumonia at the European Gaza Hospital: a clinical audit.1 passage
• Insurance coverage and financing landscape for HIV treatment and prevention in the USA.1 passage
• Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression.1 passage
• Integrating a public health and human rights approach into mental health services for Palestinians in the Gaza Strip.1 passage
• Integration of mental health and psychosocial support services into primary health care in Gaza: a cross-sectional evaluation.1 passage
• Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial.1 passage
• Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting.1 passage
• Interim findings from first-dose mass COVID-19 vaccination roll-out and COVID-19 hospital admissions in Scotland: a national prospective cohort study.1 passage
• Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study.1 passage
• Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin-piperaquine versus intermittent preventive treatment with sulfadoxine-pyrimethamine for the control of malaria during pregnancy in western Kenya: an open-label, three-group, randomised controlled superiority trial.1 passage
• International cooperation to improve access to and sustain effectiveness of antimicrobials.1 passage
• International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.1 passage
• Interpretation of the evidence for the efficacy and safety of statin therapy.1 passage
• Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma.1 passage
• Intervention strategies to improve nutrition and health behaviours before conception.1 passage
• Interventions to close the divide for women with breast and cervical cancer between low-income and middle-income countries and high-income countries.1 passage
• Interventions to prevent and reduce physician burnout: a systematic review and meta-analysis.1 passage
• Interventions to reduce unnecessary caesarean sections in healthy women and babies.1 passage
• Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicentre, prospective, randomised, open-label trial.1 passage
• Intracerebral haemorrhage: current approaches to acute management.1 passage
• Intracytoplasmic sperm injection versus conventional in-vitro fertilisation in couples with infertility in whom the male partner has normal total sperm count and motility: an open-label, randomised controlled trial.1 passage
• Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial.1 passage
• Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1-2 trial.1 passage
• Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial.1 passage
• Intrauterine insemination with ovarian stimulation versus expectant management for unexplained infertility (TUI): a pragmatic, open-label, randomised, controlled, two-centre trial.1 passage
• Intravascular imaging in coronary artery disease.1 passage
• Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.1 passage
• Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial.1 passage
• Intravenous remifentanil patient-controlled analgesia versus intramuscular pethidine for pain relief in labour (RESPITE): an open-label, multicentre, randomised controlled trial.1 passage
• Intravitreous injection of AAV2-sFLT01 in patients with advanced neovascular age-related macular degeneration: a phase 1, open-label trial.1 passage
• Invasive versus conservative strategy in patients aged 80 years or older with non-ST-elevation myocardial infarction or unstable angina pectoris (After Eighty study): an open-label randomised controlled trial.1 passage
• Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data.1 passage
• Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures.1 passage
• Investing in non-communicable disease prevention and management to advance the Sustainable Development Goals.1 passage
• Investing in non-communicable diseases: an estimation of the return on investment for prevention and treatment services.1 passage
• Investing in the foundation of sustainable development: pathways to scale up for early childhood development.1 passage
• Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd Edition.1 passage
• Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial.1 passage
• Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial.1 passage
• Iron deficiency anaemia.1 passage
• Iron deficiency.1 passage
• Irritable bowel syndrome.1 passage
• Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS).1 passage
• Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study.1 passage
• Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial.1 passage
• Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial.1 passage
• Ischaemic stroke management at Al-Shifa Hospital in the Gaza Strip: a clinical audit.1 passage
• Israel: health and beyond.1 passage
• Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial.1 passage
• Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial.1 passage
• Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial.1 passage
• Ixmyelocel-T for patients with ischaemic heart failure: a prospective randomised double-blind trial.1 passage
• KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study.1 passage
• Knee replacement.1 passage
• Knowledge and attitude of Palestinian women to contraceptives: a cross-sectional study.1 passage
• Land use, transport, and population health: estimating the health benefits of compact cities.1 passage
• Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial.1 passage
• Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial.1 passage
• Laser peripheral iridotomy for the prevention of angle closure: a single-centre, randomised controlled trial.1 passage
• Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial.1 passage
• Late Ebola virus relapse causing meningoencephalitis: a case report.1 passage
• Law enforcement and public health: recognition and enhancement of joined-up solutions.1 passage
• Leading the way towards universal health coverage: a call to action.1 passage
• Left ventricular non-compaction cardiomyopathy.1 passage
• Legionnaires' disease.1 passage
• Leishmaniasis.1 passage
• Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial.1 passage
• Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial.1 passage
• Lessons learnt from easing COVID-19 restrictions: an analysis of countries and regions in Asia Pacific and Europe.1 passage
• Levers for addressing medical underuse and overuse: achieving high-value health care.1 passage
• Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): an open-label, multicentre, randomised controlled trial.1 passage
• Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.1 passage
• Lewy body dementias.1 passage
• Liberal versus restrictive blood transfusion strategy: 3-year survival and cause of death results from the FOCUS randomised controlled trial.1 passage
• Life conditions and quality of life of Palestinians living in the Biddu Enclave: a qualitative study.1 passage
• Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study.1 passage
• Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study.1 passage
• Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility.1 passage
• Livebirth after uterus transplantation.1 passage
• Liver cirrhosis.1 passage
• Living kidney donation: outcomes, ethics, and uncertainty.1 passage
• Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study.1 passage
• Local, national, and regional viral haemorrhagic fever pandemic potential in Africa: a multistage analysis.1 passage
• Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.1 passage
• Long term effects of once-only flexible sigmoidoscopy screening after 17 years of follow-up: the UK Flexible Sigmoidoscopy Screening randomised controlled trial.1 passage
• Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals.1 passage
• Long-acting cabotegravir and rilpivirine dosed every 2 months in adults with HIV-1 infection (ATLAS-2M), 48-week results: a randomised, multicentre, open-label, phase 3b, non-inferiority study.1 passage
• Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial.1 passage
• Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial.1 passage
• Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys.1 passage
• Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial.1 passage
• Long-term care system for older adults in China: policy landscape, challenges, and future prospects.1 passage
• Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial.1 passage
• Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study.1 passage
• Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data.1 passage
• Long-term effects of radiation exposure on health.1 passage
• Long-term efficacy and safety of drug-coated balloons versus drug-eluting stents for small coronary artery disease (BASKET-SMALL 2): 3-year follow-up of a randomised, non-inferiority trial.1 passage
• Long-term evidence for the effect of pay-for-performance in primary care on mortality in the UK: a population study.1 passage
• Long-term health effects after conflict-related traumatic amputation among patients in Gaza.1 passage
• Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial.1 passage
• Long-term mortality after blood pressure-lowering and lipid-lowering treatment in patients with hypertension in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Legacy study: 16-year follow-up results of a randomised factorial trial.1 passage
• Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial.1 passage
• Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study.1 passage
• Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial.1 passage
• Long-term safety and efficacy of veverimer in patients with metabolic acidosis in chronic kidney disease: a multicentre, randomised, blinded, placebo-controlled, 40-week extension.1 passage
• Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.1 passage
• Low back pain.1 passage
• Low back pain: a call for action.1 passage
• Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial.1 passage
• Low-molecular-weight heparin and recurrent placenta-mediated pregnancy complications: a meta-analysis of individual patient data from randomised controlled trials.1 passage
• Lung cancer.1 passage
• Lung cancer: current therapies and new targeted treatments.1 passage
• MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study.1 passage
• MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study.1 passage
• Machine learning-based prediction of adverse events following an acute coronary syndrome (PRAISE): a modelling study of pooled datasets.1 passage
• Macroeconomic implications of population ageing and selected policy responses.1 passage
• Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.1 passage
• Major surgery in south India: a retrospective audit of hospital claim data from a large community health insurance programme.1 passage
• Malaria.1 passage
• Male infertility.1 passage
• Male sex workers: practices, contexts, and vulnerabilities for HIV acquisition and transmission.1 passage
• Management of acute aortic dissection.1 passage
• Management of acute ischaemic stroke at Nasser Hospital, Gaza Strip: a clinical audit.1 passage
• Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial.1 passage
• Management of chronic obstructive pulmonary disease exacerbations at the Nasser Medical Complex: a clinical audit.1 passage
• Management of cut wounds and lacerations in the Gaza Strip: a prospective clinical audit.1 passage
• Management of disease-related malnutrition for patients being treated in hospital.1 passage
• Management of drug-resistant tuberculosis.1 passage
• Management of frailty: opportunities, challenges, and future directions.1 passage
• Management of multimorbidity using a patient-centred care model: a pragmatic cluster-randomised trial of the 3D approach.1 passage
• Management of obesity.1 passage
• Management of obesity: improvement of health-care training and systems for prevention and care.1 passage
• Management of opioid use disorder in the USA: present status and future directions.1 passage
• Management of patients at risk of acute kidney injury.1 passage
• Management of pregnancy loss in the first trimester: a retrospective audit.1 passage
• Management strategies and future challenges for aortic valve disease.1 passage
• Management strategies and future directions for systemic lupus erythematosus in adults.1 passage
• Managing the public-private mix to achieve universal health coverage.1 passage
• Manifesto for a healthy and health-creating society.1 passage
• Mapping diphtheria-pertussis-tetanus vaccine coverage in Africa, 2000-2016: a spatial and temporal modelling study.1 passage
• Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017.1 passage
• Mapping global trends in vaccine confidence and investigating barriers to vaccine uptake: a large-scale retrospective temporal modelling study.1 passage
• Mapping the burden of cholera in sub-Saharan Africa and implications for control: an analysis of data across geographical scales.1 passage
• Mapping the global endemicity and clinical burden of Plasmodium vivax, 2000-17: a spatial and temporal modelling study.1 passage
• Mapping the global prevalence, incidence, and mortality of Plasmodium falciparum, 2000-17: a spatial and temporal modelling study.1 passage
• Mapping the playing field-a novel web-based strategy to identify non-governmental actors in global surgery.1 passage
• Mapping under-5 and neonatal mortality in Africa, 2000-15: a baseline analysis for the Sustainable Development Goals.1 passage
• Masitinib for treatment of severely symptomatic indolent systemic mastocytosis: a randomised, placebo-controlled, phase 3 study.1 passage
• Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events.1 passage
• Mass incarceration, public health, and widening inequality in the USA.1 passage
• Massive misuse of antibiotics by university students in China: a cross-sectional survey.1 passage
• Maternal and child health in Israel: building lives.1 passage
• Maternal and child health outcomes and intensity of conflict in the occupied Palestinian territory in 2000-14: a pseudo longitudinal analysis.1 passage
• Maternal and neonatal tetanus.1 passage
• Maternal and perinatal mortality and complications associated with caesarean section in low-income and middle-income countries: a systematic review and meta-analysis.1 passage
• Maternal mortality ratios in 2852 Chinese counties, 1996-2015, and achievement of Millennium Development Goal 5 in China: a subnational analysis of the Global Burden of Disease Study 2016.1 passage
• Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): health status analysis of a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Maximising access to achieve appropriate human antimicrobial use in low-income and middle-income countries.1 passage
• Measles.1 passage
• Measuring human capital: a systematic analysis of 195 countries and territories, 1990-2016.1 passage
• Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016.1 passage
• Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016.1 passage
• Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1.1 passage
• Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015.1 passage
• Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.1 passage
• Mechanical and oral antibiotic bowel preparation versus no bowel preparation for elective colectomy (MOBILE): a multicentre, randomised, parallel, single-blinded trial.1 passage
• Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial.1 passage
• Mechanisms underlying apathy in Parkinson's disease.1 passage
• Media reports reveal political interference at the US CDC.1 passage
• Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial.1 passage
• Medical students for health-care staff shortages during the COVID-19 pandemic.1 passage
• Medically assisted reproduction and birth outcomes: a within-family analysis using Finnish population registers.1 passage
• Medication adherence by Palestine refugees living in Jordan who have diabetes: a cross-sectional study.1 passage
• Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases.1 passage
• Melanoma.1 passage
• Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis.1 passage
• Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies.1 passage
• Mental health and quality of life of elderly people in the Bethlehem district: a cross-sectional study.1 passage
• Mental illness and suicide among physicians.1 passage
• Mesh versus suture repair of umbilical hernia in adults: a randomised, double-blind, controlled, multicentre trial.1 passage
• Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT).1 passage
• Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial.1 passage
• Methadone continuation versus forced withdrawal on incarceration in a combined US prison and jail: a randomised, open-label trial.1 passage
• Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial.1 passage
• Metronomic capecitabine as adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma: a multicentre, open-label, parallel-group, randomised, controlled, phase 3 trial.1 passage
• Microvascular and endothelial function for risk prediction in dengue: an observational study.1 passage
• Middle East respiratory syndrome.2 passages
• Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial.1 passage
• Migraine.1 passage
• Migraine: disease characterisation, biomarkers, and precision medicine.1 passage
• Migraine: epidemiology and systems of care.1 passage
• Migraine: integrated approaches to clinical management and emerging treatments.1 passage
• Militaries and global health: peace, conflict, and disaster response.1 passage
• Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss.1 passage
• Mitochondrial medicine in the omics era.1 passage
• Mitral valve disease--current management and future challenges.1 passage
• Mobilisation of public support for policy actions to prevent obesity.1 passage
• Mobilising evidence, data, and resources to achieve global maternal and child undernutrition targets and the Sustainable Development Goals: an agenda for action.1 passage
• Modern contraceptive use, unmet need, and demand satisfied among women of reproductive age who are married or in a union in the focus countries of the Family Planning 2020 initiative: a systematic analysis using the Family Planning Estimation Tool.1 passage
• Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study.1 passage
• Molecular alterations in triple-negative breast cancer-the road to new treatment strategies.1 passage
• Molecular mechanisms of myocardial nitroso-redox imbalance during on-pump cardiac surgery.1 passage
• Monitoring and evaluating surgical care: defining perioperative mortality rate and standardising data collection.1 passage
• Monotherapy with a P2Y1 passage
• Monthly sulfadoxine-pyrimethamine versus dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a double-blind, randomised, controlled, superiority trial.1 passage
• Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis.1 passage
• Morbidity patterns among hospitalised Palestine refugees from Syria in Jordan: a population-based study.1 passage
• More talk than action: gender and ethnic diversity in leading public health universities.1 passage
• Morphine versus fentanyl for spinal post-caesarean analgesia: a randomised controlled trial.1 passage
• Morphological suitability for endovascular repair, non-intervention rates, and operative mortality in women and men assessed for intact abdominal aortic aneurysm repair: systematic reviews with meta-analysis.1 passage
• Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data.1 passage
• Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.1 passage
• Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.1 passage
• Mortality decrease according to socioeconomic groups during the economic crisis in Spain: a cohort study of 36 million people.1 passage
• Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries.1 passage
• Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.1 passage
• Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries.1 passage
• Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data.1 passage
• Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis.1 passage
• Mortality in children, adolescents, and adults with attention deficit hyperactivity disorder: a nationwide cohort study.1 passage
• Mortality in patients treated with extended duration dual antiplatelet therapy after drug-eluting stent implantation: a pairwise and Bayesian network meta-analysis of randomised trials.1 passage
• Mortality of people with chronic fatigue syndrome: a retrospective cohort study in England and Wales from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive Search (CRIS) Register.1 passage
• Mortality risk attributable to high and low ambient temperature: a multicountry observational study.1 passage
• Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis.1 passage
• Mortality risks associated with emergency admissions during weekends and public holidays: an analysis of electronic health records.1 passage
• Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Motivators and barriers to mammography screening uptake by female health-care workers in primary health-care centres: a cross-sectional study.1 passage
• Moving towards universal health coverage: lessons from 11 country studies.1 passage
• Multidimensional endotypes of asthma: topological data analysis of cross-sectional clinical, pathological, and immunological data.1 passage
• Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial.1 passage
• Multimodality imaging in ischaemic heart failure.1 passage
• Multiple myeloma.2 passages
• Multiple sclerosis.1 passage
• Muscular dystrophies.1 passage
• Musculoskeletal trauma and all-cause mortality in India: a multicentre prospective cohort study.1 passage
• Music as an aid for postoperative recovery in adults: a systematic review and meta-analysis.1 passage
• NCD Countdown 2030: pathways to achieving Sustainable Development Goal target 3.4.1 passage
• NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4.1 passage
• NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial.1 passage
• Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational first-in-human trial.1 passage
• Nasopharyngeal carcinoma.2 passages
• National spending on health by source for 184 countries between 2013 and 2040.1 passage
• Nations within a nation: variations in epidemiological transition across the states of India, 1990-2016 in the Global Burden of Disease Study.1 passage
• Natural killer cell maturation markers in the human liver and expansion of an NKG2C+KIR+ population.1 passage
• Neglected tropical diseases: progress towards addressing the chronic pandemic.1 passage
• Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial.1 passage
• Neonatal sepsis.1 passage
• Neonatal surgery in Africa: a systematic review and meta-analysis of challenges of management and outcome.1 passage
• Neural respiratory drive and symptoms that limit exercise in chronic obstructive pulmonary disease.1 passage
• Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial.1 passage
• Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial.1 passage
• Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.1 passage
• Neuromodulation for chronic pain.1 passage
• Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial.1 passage
• New WHO prevalence estimates of mental disorders in conflict settings: a systematic review and meta-analysis.1 passage
• New Zealand health system: universalism struggles with persisting inequities.1 passage
• New and emerging targeted treatments in advanced non-small-cell lung cancer.1 passage
• New dimensions for hospital services and early detection of disease: a Review from the Lancet Commission into liver disease in the UK.1 passage
• New directions in the treatment of opioid withdrawal.1 passage
• New psychoactive substances: challenges for drug surveillance, control, and public health responses.1 passage
• Next generation maternal health: external shocks and health-system innovations.1 passage
• Nifedipine versus atosiban for threatened preterm birth (APOSTEL III): a multicentre, randomised controlled trial.1 passage
• Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial.1 passage
• Nociplastic pain: towards an understanding of prevalent pain conditions.1 passage
• Non-Hodgkin lymphoma.1 passage
• Non-alcoholic fatty liver disease.1 passage
• Non-communicable disease syndemics: poverty, depression, and diabetes among low-income populations.1 passage
• Non-communicable diseases among Palestinian refugees from Syria: a cross-sectional study on prevalence, case management, access to and utilisation of UNRWA Health Services.1 passage
• Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data.1 passage
• Non-pharmaceutical interventions, vaccination, and the SARS-CoV-2 delta variant in England: a mathematical modelling study.1 passage
• Non-specific low back pain.1 passage
• Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial.1 passage
• Novel paradigms in systemic lupus erythematosus.1 passage
• Novel plasma microRNA biomarkers for the identification of colitis-associated carcinoma.1 passage
• Novel treatment strategies in rheumatoid arthritis.1 passage
• Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study.1 passage
• Nuclear disasters and health: lessons learned, challenges, and proposals.1 passage
• Nurturing care: promoting early childhood development.1 passage
• Nutrition in adolescent growth and development.1 passage
• Obesity management as a primary treatment goal for type 2 diabetes: time to reframe the conversation.1 passage
• Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.1 passage
• Occurrence of death and stroke in patients in 47 countries 1 year after presenting with atrial fibrillation: a cohort study.1 passage
• Oesophageal cancer.1 passage
• Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial.1 passage
• Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial.1 passage
• Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.1 passage
• Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001): an open-label, non-inferiority, randomised controlled trial.1 passage
• On the road to universal health care in Indonesia, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials.1 passage
• Once-daily, subcutaneous vosoritide therapy in children with achondroplasia: a randomised, double-blind, phase 3, placebo-controlled, multicentre trial.1 passage
• Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial.1 passage
• Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial.1 passage
• Once-weekly dulaglutide versus bedtime insulin glargine, both in combination with prandial insulin lispro, in patients with type 2 diabetes (AWARD-4): a randomised, open-label, phase 3, non-inferiority study.1 passage
• Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial.1 passage
• One size does not fit all. Management of the laparoscopic adjustable gastric band in pregnancy: a national prospective cohort study.1 passage
• Opportunities, resources, and techniques for implementing genomics in clinical care.1 passage
• Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial.1 passage
• Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials.1 passage
• Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open-label, randomised controlled trial.1 passage
• Oral amoxicillin compared with injectable procaine benzylpenicillin plus gentamicin for treatment of neonates and young infants with fast breathing when referral is not possible: a randomised, open-label, equivalence trial.1 passage
• Oral anticoagulants for stroke prevention in atrial fibrillation: current status, special situations, and unmet needs.1 passage
• Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial.1 passage
• Oral diseases: a global public health challenge.1 passage
• Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial.1 passage
• Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial.1 passage
• Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety.1 passage
• Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial.1 passage
• Oral rimegepant for preventive treatment of migraine: a phase 2/3, randomised, double-blind, placebo-controlled trial.1 passage
• Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial.1 passage
• Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial.1 passage
• Oral versus intravenous high-dose methylprednisolone for treatment of relapses in patients with multiple sclerosis (COPOUSEP): a randomised, controlled, double-blind, non-inferiority trial.1 passage
• Oral zinc supplementation for children with acute diarrhoea: a quasi-experimental study.1 passage
• Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial.1 passage
• Organisational best practices towards gender equality in science and medicine.1 passage
• Origins of lifetime health around the time of conception: causes and consequences.1 passage
• Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial.1 passage
• Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials.1 passage
• Osteoarthritis.2 passages
• Osteogenesis imperfecta.1 passage
• Osteoporosis.1 passage
• Out-of-hospital cardiac arrest: current concepts.1 passage
• Out-of-hospital cardiac arrest: in-hospital intervention strategies.1 passage
• Out-of-hospital cardiac arrest: prehospital management.1 passage
• Out-of-pocket expenses incurred by patients obtaining free breast cancer care in Haiti.1 passage
• Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April-May, 2018: an epidemiological study.1 passage
• Outcome and undertreatment of mitral regurgitation: a community cohort study.1 passage
• Outcomes after thrombus aspiration for ST elevation myocardial infarction: 1-year follow-up of the prospective randomised TOTAL trial.1 passage
• Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.1 passage
• Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.1 passage
• Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial.1 passage
• Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial.1 passage
• Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial.1 passage
• P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study.1 passage
• PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial.1 passage
• PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin Study Group.1 passage
• Pain management during labour at the El-Emarati Hospital: a clinical audit.1 passage
• Pain management in adults during long-bone fracture reduction in the Gaza Strip: a clinical audit.1 passage
• Palatal fistula risk after primary palatoplasty: a retrospective comparison of humanitarian operations and tertiary hospitals.1 passage
• Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease.1 passage
• Pancreatic cancer.2 passages
• Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial.1 passage
• Parental education and inequalities in child mortality: a global systematic review and meta-analysis.1 passage
• Parkinson's disease.2 passages
• Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial.1 passage
• Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial.1 passage
• Participation of people living with disabilities in physical activity: a global perspective.1 passage
• Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995-2050.1 passage
• Patchy progress on obesity prevention: emerging examples, entrenched barriers, and new thinking.1 passage
• Pathogenetic insights from the treatment of rheumatoid arthritis.1 passage
• Pathology of congenital Zika syndrome in Brazil: a case series.1 passage
• Pathophysiological advances in membranous nephropathy: time for a shift in patient's care.1 passage
• Pathophysiology, research challenges, and clinical management of smoke inhalation injury.1 passage
• Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study.1 passage
• Patient-reported outcomes with anastrozole versus tamoxifen for postmenopausal patients with ductal carcinoma in situ treated with lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial.1 passage
• Patients' satisfaction with the non-communicable diseases services provided at UNRWA health centres in Gaza governorates: a cross-sectional study.1 passage
• Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial.1 passage
• Peer-supported self-management for people discharged from a mental health crisis team: a randomised controlled trial.1 passage
• Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial.1 passage
• Pelvic floor muscle training for secondary prevention of pelvic organ prolapse (PREVPROL): a multicentre randomised controlled trial.1 passage
• Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study.1 passage
• Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study.1 passage
• Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial.1 passage
• Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial.1 passage
• Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial.1 passage
• Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006).1 passage
• Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study.1 passage
• Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial.1 passage
• Pemphigus.1 passage
• Penile allotransplantation for penis amputation following ritual circumcision: a case report with 24 months of follow-up.1 passage
• Peptic ulcer disease.1 passage
• Perceptions of health-care professionals about quality of care and barriers to management of war injuries in Gaza Strip: a qualitative analysis.1 passage
• Percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial.1 passage
• Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial.1 passage
• Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial.1 passage
• Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial.1 passage
• Percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass grafting in left main coronary artery disease: an individual patient data meta-analysis.1 passage
• Percutaneous coronary interventional strategies for treatment of in-stent restenosis: a network meta-analysis.1 passage
• Percutaneous tibial nerve stimulation versus sham electrical stimulation for the treatment of faecal incontinence in adults (CONFIDeNT): a double-blind, multicentre, pragmatic, parallel-group, randomised controlled trial.1 passage
• Perforated peptic ulcer.1 passage
• Performance of private sector health care: implications for universal health coverage.1 passage
• Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.1 passage
• Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study.1 passage
• Perioperative opioid analgesia-when is enough too much? A review of opioid-induced tolerance and hyperalgesia.1 passage
• Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study.1 passage
• Perioperative thermoregulation and heat balance.1 passage
• Periprosthetic joint infection.1 passage
• Personalised perioperative care by e-health after intermediate-grade abdominal surgery: a multicentre, single-blind, randomised, placebo-controlled trial.1 passage
• Personality disorder across the life course.1 passage
• Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial.1 passage
• Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain.1 passage
• Pharmacogenomics.1 passage
• Pharmacological and emerging therapies in the treatment of chronic angina.1 passage
• Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis.1 passage
• Pharmacological lipid-modification therapies for prevention of ischaemic heart disease: current and future options.1 passage
• Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis.1 passage
• Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments.1 passage
• Phosphate as a cardiovascular risk factor: effects on vascular and endothelial function.1 passage
• Phosphoinositide 3-kinase-related overgrowth: cellular phenotype and future therapeutic options.1 passage
• Physical activity behaviours in adolescence: current evidence and opportunities for intervention.1 passage
• Physical activity in relation to urban environments in 14 cities worldwide: a cross-sectional study.1 passage
• Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis.1 passage
• Physical health indicators in major mental illness: data from the Quality and Outcome Framework in the UK.1 passage
• Physical punishment and child outcomes: a narrative review of prospective studies.1 passage
• Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial.1 passage
• Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study.1 passage
• Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial.1 passage
• Planetary health: protecting human health on a rapidly changing planet.1 passage
• Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.1 passage
• Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis.1 passage
• Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial.1 passage
• Plaster cast versus functional brace for non-surgical treatment of Achilles tendon rupture (UKSTAR): a multicentre randomised controlled trial and economic evaluation.1 passage
• Platelet function monitoring to adjust antiplatelet therapy in elderly patients stented for an acute coronary syndrome (ANTARCTIC): an open-label, blinded-endpoint, randomised controlled superiority trial.1 passage
• Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.1 passage
• Pleiotropic effects of statins in hypercholesterolaemia: a prospective observational study using a lipoproteomic based approach.1 passage
• Police killings and their spillover effects on the mental health of black Americans: a population-based, quasi-experimental study.1 passage
• Polonium-210 poisoning: a first-hand account.1 passage
• Polymyalgia rheumatica.1 passage
• Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.1 passage
• Population effectiveness of opportunistic chlamydia testing in primary care in Australia: a cluster-randomised controlled trial.1 passage
• Population health and regional variations of disease burden in Japan, 1990-2015: a systematic subnational analysis for the Global Burden of Disease Study 2015.1 passage
• Population health in an era of rising income inequality: USA, 1980-2015.1 passage
• Population screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial.1 passage
• Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis.1 passage
• Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial.1 passage
• Post-deployment screening for mental disorders and tailored advice about help-seeking in the UK military: a cluster randomised controlled trial.1 passage
• Post-listing survival for highly sensitised patients on the UK kidney transplant waiting list: a matched cohort analysis.1 passage
• Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial.1 passage
• Postgraduate training abroad and migration intentions of medical doctors and students in Gaza: a cross-sectional survey.1 passage
• Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial.1 passage
• Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis.1 passage
• Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study.1 passage
• Prasugrel-based de-escalation of dual antiplatelet therapy after percutaneous coronary intervention in patients with acute coronary syndrome (HOST-REDUCE-POLYTECH-ACS): an open-label, multicentre, non-inferiority randomised trial.1 passage
• Pre-eclampsia.2 passages
• Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.1 passage
• Pre-hospital emergency medicine.1 passage
• Preconception health in England: a proposal for annual reporting with core metrics.1 passage
• Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.1 passage
• Prediction of mortality benefit based on periodic repolarisation dynamics in patients undergoing prophylactic implantation of a defibrillator: a prospective, controlled, multicentre cohort study.1 passage
• Prediction of perinatal depression from adolescence and before conception (VIHCS): 20-year prospective cohort study.1 passage
• Prednisone versus prednisone plus ciclosporin versus prednisone plus methotrexate in new-onset juvenile dermatomyositis: a randomised trial.1 passage
• Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial.1 passage
• Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.1 passage
• Prenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study.1 passage
• Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial.1 passage
• Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study.1 passage
• Prepregnancy and early pregnancy calcium supplementation among women at high risk of pre-eclampsia: a multicentre, double-blind, randomised, placebo-controlled trial.1 passage
• Presurgical entorhinal cortex volume and postoperative seizure outcome in temporal lobe epilepsy.1 passage
• Prevalence and characteristics of Palestine refugee mothers at risk of postpartum depression in Amman, Jordan: a cross-sectional study.1 passage
• Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study.1 passage
• Prevalence of SARS-CoV-2 antibodies in a large nationwide sample of patients on dialysis in the USA: a cross-sectional study.1 passage
• Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study.1 passage
• Prevalence of chronic diseases in older Palestinian adults and common pharmacological interventions: a cross-sectional study.1 passage
• Prevalence of chronic pain in low-income and middle-income countries: a systematic review and meta-analysis.1 passage
• Prevalence of negative child disciplinary practices and its associated factors as reported by mothers in the West Bank: a cross-sectional study.1 passage
• Prevalence of overweight, obesity, and associated factors among adolescents in the occupied Palestinian territory: a cross-sectional study.1 passage
• Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project).1 passage
• Prevalence, risk factors, and management of asthma in China: a national cross-sectional study.1 passage
• Prevention and treatment of low back pain: evidence, challenges, and promising directions.1 passage
• Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial.1 passage
• Prevention of stroke: a global perspective.1 passage
• Prevention of transmission of HIV, hepatitis B virus, hepatitis C virus, and tuberculosis in prisoners.1 passage
• Prevention of violence against women and girls: lessons from practice.1 passage
• Prevention of violence against women and girls: what does the evidence say?1 passage
• Primary biliary cholangitis.1 passage
• Primary biliary cirrhosis.1 passage
• Primary brain tumours in adults.1 passage
• Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.1 passage
• Primary chemotherapy versus primary surgery for newly diagnosed advanced ovarian cancer (CHORUS): an open-label, randomised, controlled, non-inferiority trial.1 passage
• Primary glomerulonephritides.1 passage
• Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention.1 passage
• Primary prevention of ischaemic heart disease: populations, individuals, and health professionals.1 passage
• Primary sclerosing cholangitis.1 passage
• Principles of DNA methylation and their implications for biology and medicine.1 passage
• Prioritisation of surgery in the National Health Strategic Plans of Africa: a systematic review.1 passage
• Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns).1 passage
• Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study.1 passage
• Progress in adolescent health and wellbeing: tracking 12 headline indicators for 195 countries and territories, 1990-2016.1 passage
• Progress in clinical research in surgery and IDEAL.1 passage
• Progress in physical activity over the Olympic quadrennium.1 passage
• Progressive exercise compared with best practice advice, with or without corticosteroid injection, for the treatment of patients with rotator cuff disorders (GRASP): a multicentre, pragmatic, 2 × 2 factorial, randomised controlled trial.1 passage
• Progressive multiple sclerosis: prospects for disease therapy, repair, and restoration of function.1 passage
• Prohibit, constrain, encourage, or purchase: how should we engage with the private health-care sector?1 passage
• Projections to achieve minimum surgical rate threshold: an observational study.1 passage
• Promoting COVID-19 vaccine acceptance: recommendations from the Lancet Commission on Vaccine Refusal, Acceptance, and Demand in the USA.1 passage
• Promoting school climate and health outcomes with the SEHER multi-component secondary school intervention in Bihar, India: a cluster-randomised controlled trial.1 passage
• Prophylactic antibiotics after acute stroke for reducing pneumonia in patients with dysphagia (STROKE-INF): a prospective, cluster-randomised, open-label, masked endpoint, controlled clinical trial.1 passage
• Prophylactic antibiotics in the prevention of infection after operative vaginal delivery (ANODE): a multicentre randomised controlled trial.1 passage
• Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial.1 passage
• Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial.1 passage
• Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial.1 passage
• Proposed minimum rates of surgery to support desirable health outcomes: an observational study based on four strategies.1 passage
• Prostate cancer.2 passages
• Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study.1 passage
• Protecting human security: proposals for the G7 Ise-Shima Summit in Japan.1 passage
• Protection by vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh: a cluster-randomised trial.1 passage
• Proteomic analysis to identify biomarkers in the primary tumour that predict response to neoadjuvant chemotherapy in liver metastases.1 passage
• Providing incentives to share data early in health emergencies: the role of journal editors.1 passage
• Provision of social norm feedback to high prescribers of antibiotics in general practice: a pragmatic national randomised controlled trial.1 passage
• Psoriasis.2 passages
• Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models.1 passage
• Public health implications of legalising the production and sale of cannabis for medicinal and recreational use.1 passage
• Public health information in crisis-affected populations: a review of methods and their use for advocacy and action.1 passage
• Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study.1 passage
• Putting polypills into practice: challenges and lessons learned.1 passage
• Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.1 passage
• Quality maternity care for every woman, everywhere: a call to action.1 passage
• Quality of Early Essential Newborn Care in hospitals in Gaza: a pre-intervention and post-intervention study.1 passage
• Quality of life, primary traumatisation, and positive and negative affects in primary school students in the Gaza Strip.1 passage
• Quality of primary health care in China: challenges and recommendations.1 passage
• Quantifying the burden of stillbirths before 28 weeks of completed gestational age in high-income countries: a population-based study of 19 European countries.1 passage
• Quantitative assessment of the cell surface proteome to identify novel therapeutic targets in cholangiocarcinoma.1 passage
• Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review.1 passage
• Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial.1 passage
• Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial.1 passage
• Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial.1 passage
• Radiation exposure in relation to the arterial access site used for diagnostic coronary angiography and percutaneous coronary intervention: a systematic review and meta-analysis.1 passage
• Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.1 passage
• Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial.1 passage
• Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.1 passage
• Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial.1 passage
• Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial.1 passage
• Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Rapid urine-based screening for tuberculosis in HIV-positive patients admitted to hospital in Africa (STAMP): a pragmatic, multicentre, parallel-group, double-blind, randomised controlled trial.1 passage
• Rate control in atrial fibrillation.1 passage
• Rates of caesarean section and total volume of surgery in Sierra Leone: a retrospective survey.1 passage
• Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study.1 passage
• ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study.1 passage
• Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002).1 passage
• Readmission destination and risk of mortality after major surgery: an observational cohort study.1 passage
• Real-time continuous glucose monitoring in adults with type 1 diabetes and impaired hypoglycaemia awareness or severe hypoglycaemia treated with multiple daily insulin injections (HypoDE): a multicentre, randomised controlled trial.1 passage
• Recognition and management of acute kidney injury in the International Society of Nephrology 0by25 Global Snapshot: a multinational cross-sectional study.1 passage
• Recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-oedema: a phase 2, multicentre, randomised, double-blind, placebo-controlled crossover trial.1 passage
• Rectal bleeding and endoscopy need in Sierra Leone: results of a nationwide, community-based survey.1 passage
• Recurrence of breast cancer after regional or general anaesthesia: a randomised controlled trial.1 passage
• Recurrent failings of medical humanitarianism: intractable, ignored, or just exaggerated?1 passage
• Recurrent miscarriage: evidence to accelerate action.1 passage
• Red blood-cell alloantibodies in multiply transfused patients in the occupied Palestinian territory: a pilot study.1 passage
• Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis.1 passage
• Redevelopment and validation of the SYNTAX score II to individualise decision making between percutaneous and surgical revascularisation in patients with complex coronary artery disease: secondary analysis of the multicentre randomised controlled SYNTAXES trial with external cohort validation.1 passage
• Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial.1 passage
• Reducing the health effects of hot weather and heat extremes: from personal cooling strategies to green cities.1 passage
• Reductions in pregnancy rates in the USA with long-acting reversible contraception: a cluster randomised trial.1 passage
• Refractive surgery.1 passage
• Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Regulation of neutrophilic inflammation in lung injury induced by community-acquired pneumonia.1 passage
• Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.1 passage
• Reimagining WHO: leadership and action for a new Director-General.1 passage
• Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study.1 passage
• Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study.1 passage
• Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial.1 passage
• Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.1 passage
• Renal cancer.1 passage
• Reproductive, maternal, newborn, and child health: key messages from Disease Control Priorities 3rd Edition.1 passage
• Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study.1 passage
• Responding to global stimulant use: challenges and opportunities.1 passage
• Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration.1 passage
• Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial.1 passage
• Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial.1 passage
• Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial.1 passage
• Retinal vascular occlusions.1 passage
• Revascularisation of renal artery stenosis as a therapy for heart failure: an observational cohort study.1 passage
• Revisiting Alma-Ata: what is the role of primary health care in achieving the Sustainable Development Goals?1 passage
• Revisiting maternal and child undernutrition in low-income and middle-income countries: variable progress towards an unfinished agenda.1 passage
• Rheumatoid arthritis.1 passage
• Rhythm control in atrial fibrillation.1 passage
• Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial.1 passage
• Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial.1 passage
• Risk factors and early origins of chronic obstructive pulmonary disease.1 passage
• Risk factors for asthma: is prevention possible?1 passage
• Risk factors for vitamin A and vitamin D deficiencies in children younger than 5 years in the occupied Palestinian territory: a cross-sectional study.1 passage
• Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study.1 passage
• Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study.1 passage
• Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis.1 passage
• Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.1 passage
• Rituximab and dose-dense chemotherapy for adults with Burkitt's lymphoma: a randomised, controlled, open-label, phase 3 trial.1 passage
• Rituximab as second-line treatment for adult immune thrombocytopenia (the RITP trial): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial.1 passage
• Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial.1 passage
• Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial.1 passage
• Robot assisted training for the upper limb after stroke (RATULS): a multicentre randomised controlled trial.1 passage
• Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study.1 passage
• Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial.1 passage
• Role of a neurokinin B receptor antagonist in the regulation of ovarian function in healthy women.1 passage
• Role of melanocortin signalling in the preference for dietary macronutrients in human beings.1 passage
• Role of retinoic acid in the stability of the T-helper-type 1 lineage and implications for autoimmunity.1 passage
• Role of vitamin D in endothelial function and endothelial repair in clinically stable systemic lupus erythematosus.1 passage
• Romiplostim in children with immune thrombocytopenia: a phase 3, randomised, double-blind, placebo-controlled study.1 passage
• Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial.1 passage
• Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT).1 passage
• Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial.1 passage
• Rubella.1 passage
• Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial.1 passage
• SARS-CoV-2 and viral sepsis: observations and hypotheses.1 passage
• SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates.1 passage
• SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN).1 passage
• SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications.1 passage
• SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials.1 passage
• SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials.1 passage
• ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data.1 passage
• Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial.1 passage
• Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial.1 passage
• Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial.1 passage
• Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia.1 passage
• Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Safety and efficacy of subcutaneous ianalumab (VAY736) in patients with primary Sjögren's syndrome: a randomised, double-blind, placebo-controlled, phase 2b dose-finding trial.1 passage
• Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial.1 passage
• Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.1 passage
• Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Safety and efficacy of upadacitinib in patients with active rheumatoid arthritis refractory to biologic disease-modifying anti-rheumatic drugs (SELECT-BEYOND): a double-blind, randomised controlled phase 3 trial.1 passage
• Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial.1 passage
• Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial.1 passage
• Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.1 passage
• Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial.1 passage
• Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind, placebo-controlled trial.1 passage
• Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial.1 passage
• Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial.1 passage
• Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trial.1 passage
• Safety and immunogenicity of a recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in Sierra Leone: a single-centre, randomised, double-blind, placebo-controlled, phase 2 trial.1 passage
• Safety and immunogenicity of a tetravalent dengue vaccine in children aged 2-17 years: a randomised, placebo-controlled, phase 2 trial.1 passage
• Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia.1 passage
• Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial.1 passage
• Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial.1 passage
• Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial.1 passage
• Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.1 passage
• Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials.1 passage
• Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials.1 passage
• Safety and performance of the second-generation drug-eluting absorbable metal scaffold in patients with de-novo coronary artery lesions (BIOSOLVE-II): 6 month results of a prospective, multicentre, non-randomised, first-in-man trial.1 passage
• Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.1 passage
• Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial.1 passage
• Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial.1 passage
• Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial.1 passage
• Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.1 passage
• Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study.1 passage
• Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2·4 mg for weight management: a randomised, controlled, phase 1b trial.1 passage
• Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial.1 passage
• Sarcopenia.1 passage
• Scaling up physical activity interventions worldwide: stepping up to larger and smarter approaches to get people moving.1 passage
• Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model.1 passage
• Schizophrenia.1 passage
• School-based suicide prevention programmes: the SEYLE cluster-randomised, controlled trial.1 passage
• Screening and brief intervention for obesity in primary care: a parallel, two-arm, randomised trial.1 passage
• Screening for fetal growth restriction with universal third trimester ultrasonography in nulliparous women in the Pregnancy Outcome Prediction (POP) study: a prospective cohort study.1 passage
• Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial.1 passage
• Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy.1 passage
• Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): a double-blind, parallel-group, randomised, active-controlled, phase 3b trial.1 passage
• Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.1 passage
• Securing a sustainable and fit-for-purpose UK health and care workforce.1 passage
• Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial.1 passage
• Self-expanding intra-annular versus commercially available transcatheter heart valves in high and extreme risk patients with severe aortic stenosis (PORTICO IDE): a randomised, controlled, non-inferiority trial.1 passage
• Self-perceived health among children with spina bifida in the West Bank: a cross-sectional study.1 passage
• Self-reported quality of life of adolescents with cerebral palsy: a cross-sectional and longitudinal analysis.1 passage
• Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.1 passage
• Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial.1 passage
• Sepsis and septic shock.1 passage
• Septoplasty with or without concurrent turbinate surgery versus non-surgical management for nasal obstruction in adults with a deviated septum: a pragmatic, randomised controlled trial.1 passage
• Seroprevalence and humoral immune durability of anti-SARS-CoV-2 antibodies in Wuhan, China: a longitudinal, population-level, cross-sectional study.1 passage
• Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study.1 passage
• Serving transgender people: clinical care considerations and service delivery models in transgender health.1 passage
• Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care.1 passage
• Severe cutaneous adverse reactions to drugs.1 passage
• Severe extremity amputations in surviving Palestinian civilians caused by explosives fired from drones during the Gaza War.1 passage
• Sex and gender: modifiers of health, disease, and medicine.1 passage
• Shigellosis.1 passage
• Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial.1 passage
• Short-term and long-term effects of caesarean section on the health of women and children.1 passage
• Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study.1 passage
• Sickle cell disease.1 passage
• Simplified antibiotic regimens compared with injectable procaine benzylpenicillin plus gentamicin for treatment of neonates and young infants with clinical signs of possible serious bacterial infection when referral is not possible: a randomised, open-label, equivalence trial.1 passage
• Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study.1 passage
• Singapore's health-care system: key features, challenges, and shifts.1 passage
• Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial.1 passage
• Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials.1 passage
• Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial.1 passage
• Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial.1 passage
• Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.1 passage
• Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study.1 passage
• Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.1 passage
• Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.1 passage
• Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial.1 passage
• Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial.1 passage
• Small molecules, big impact: 20 years of targeted therapy in oncology.1 passage
• Smart food policies for obesity prevention.1 passage
• Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial.1 passage
• Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015.1 passage
• Social determinants of health, universal health coverage, and sustainable development: case studies from Latin American countries.1 passage
• Social network targeting to maximise population behaviour change: a cluster randomised controlled trial.1 passage
• Socioeconomic inequalities in adolescent health 2002-2010: a time-series analysis of 34 countries participating in the Health Behaviour in School-aged Children study.1 passage
• Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women.1 passage
• Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial.1 passage
• Sofosbuvir plus ribavirin for treatment of hepatitis C virus in patients co-infected with HIV (PHOTON-2): a multicentre, open-label, non-randomised, phase 3 study.1 passage
• Soil-transmitted helminth infections.1 passage
• Spatial agency among children living in the Dheisheh refugee camp in the West Bank: a qualitative investigation of space and place as risk and protection factors from political and military violence.1 passage
• Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019.1 passage
• Spending on health and HIV/AIDS: domestic health spending and development assistance in 188 countries, 1995-2015.1 passage
• Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions.1 passage
• Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial.1 passage
• Spontaneous subarachnoid haemorrhage.1 passage
• Sporadic miscarriage: evidence to provide effective care.1 passage
• Stable coronary artery disease: revascularisation and invasive strategies.1 passage
• Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival: pragmatic, multicentre, randomised controlled trial.1 passage
• State humanitarian verticalism versus universal health coverage: a century of French international health assistance revisited.1 passage
• Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.1 passage
• Status and drivers of maternal, newborn, child and adolescent health in the Islamic world: a comparative analysis.1 passage
• Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial.1 passage
• Stillbirths: economic and psychosocial consequences.1 passage
• Stillbirths: ending preventable deaths by 2030.1 passage
• Stillbirths: progress and unfinished business.1 passage
• Stillbirths: rates, risk factors, and acceleration towards 2030.1 passage
• Stillbirths: recall to action in high-income countries.1 passage
• Stopping tuberculosis: a biosocial model for sustainable development.1 passage
• Strategies and interventions for healthy adolescent growth, nutrition, and development.1 passage
• Strategies for long-term preservation of kidney graft function.1 passage
• Strengthening of accountability systems to create healthy food environments and reduce global obesity.1 passage
• Strengthening of partnerships between the public sector and faith-based groups.1 passage
• Stroke prevention in atrial fibrillation.1 passage
• Stroke rehabilitation in low-income and middle-income countries: a call to action.1 passage
• Stroke systems of care in high-income countries: what is optimal?1 passage
• Stroke systems of care in low-income and middle-income countries: challenges and opportunities.1 passage
• Stroke.2 passages
• Structural racism and health inequities in the USA: evidence and interventions.1 passage
• Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial.1 passage
• Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study.1 passage
• Subjective wellbeing, health, and ageing.1 passage
• Subnational mapping of under-5 and neonatal mortality trends in India: the Global Burden of Disease Study 2000-17.1 passage
• Suicide and suicidal behaviour.1 passage
• Surgery in district hospitals in rural Uganda-indications, interventions, and outcomes.1 passage
• Surgery versus cast immobilisation for adults with a bicortical fracture of the scaphoid waist (SWIFFT): a pragmatic, multicentre, open-label, randomised superiority trial.1 passage
• Surgical care by non-surgeons in low-income and middle-income countries: a systematic review.1 passage
• Surgical care needs of low-resource populations: an estimate of the prevalence of surgically treatable conditions and avoidable deaths in 48 countries.1 passage
• Surgical need in an ageing population: a cluster-based household survey in Nepal.1 passage
• Survival analysis for patients with cancer in Gaza applying for Israeli permits to exit the Gaza Strip for health care: a retrospective cohort study of patients from 2008 to 2017.1 passage
• Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study.1 passage
• Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial.1 passage
• Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study.1 passage
• Sustained-release dexamfetamine in the treatment of chronic cocaine-dependent patients on heroin-assisted treatment: a randomised, double-blind, placebo-controlled trial.1 passage
• Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial.1 passage
• Syndemic vulnerability and the right to health.1 passage
• Syndemics and the biosocial conception of health.1 passage
• Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway.1 passage
• Syphilis.1 passage
• Systemic amyloidosis.1 passage
• Systemic sclerosis.1 passage
• T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.1 passage
• Tachykinin neurokinin 3 receptor antagonists: a new treatment for cardiovascular disease?1 passage
• Tackling socioeconomic inequalities and non-communicable diseases in low-income and middle-income countries under the Sustainable Development agenda.1 passage
• Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre, open-label, randomised non-inferiority trial.1 passage
• Targeted-release budesonide versus placebo in patients with IgA nephropathy (NEFIGAN): a double-blind, randomised, placebo-controlled phase 2b trial.1 passage
• Targeting calcitonin gene-related peptide: a new era in migraine therapy.1 passage
• Targeting indirect pathway CD4 T-cell alloresponses in the prevention of chronic transplant rejection.1 passage
• Targeting the interleukin pathway in the treatment of asthma.1 passage
• Tasimelteon for non-24-hour sleep-wake disorder in totally blind people (SET and RESET): two multicentre, randomised, double-masked, placebo-controlled phase 3 trials.1 passage
• Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study.1 passage
• Telemedicine for management of inflammatory bowel disease (myIBDcoach): a pragmatic, multicentre, randomised controlled trial.1 passage
• Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals.1 passage
• Temporary circulatory support for cardiogenic shock.1 passage
• Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials.1 passage
• Teratogenic effects of the Zika virus and the role of the placenta.1 passage
• Testicular germ cell tumours.1 passage
• Tetanus.1 passage
• Thalassaemia.1 passage
• The 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by a changing climate.1 passage
• The 2020 report of The Lancet Countdown on health and climate change: responding to converging crises.1 passage
• The Affordable Care Act: implications for health-care equity.1 passage
• The Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomised trials in Mozambique, Pakistan, and India: an individual participant-level meta-analysis.1 passage
• The G20 and development assistance for health: historical trends and crucial questions to inform a new era.1 passage
• The Healthy Activity Program (HAP), a lay counsellor-delivered brief psychological treatment for severe depression, in primary care in India: a randomised controlled trial.1 passage
• The Institute of Medicine: ensuring integrity and independence in scientific advice on health.1 passage
• The Lancet Countdown: tracking progress on health and climate change.1 passage
• The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030.1 passage
• The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial.1 passage
• The Rohingya people of Myanmar: health, human rights, and identity.1 passage
• The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.1 passage
• The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.1 passage
• The World report on ageing and health: a policy framework for healthy ageing.1 passage
• The active intrathecal B-cell response in LGI1-antibody encephalitis.1 passage
• The burden of disease in Russia from 1980 to 2016: a systematic analysis for the Global Burden of Disease Study 2016.1 passage
• The burden of disease in older people and implications for health policy and practice.1 passage
• The burden of mental, neurological, and substance use disorders in China and India: a systematic analysis of community representative epidemiological studies.1 passage
• The changing demographics of inpatient hospice death: population-based, cross-sectional study in England, 1993-2012.1 passage
• The changing health needs of the UK population.1 passage
• The changing treatment landscape in haemophilia: from standard half-life clotting factor concentrates to gene editing.1 passage
• The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.1 passage
• The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.1 passage
• The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE).1 passage
• The double burden of malnutrition: aetiological pathways and consequences for health.1 passage
• The double challenge of resistant hypertension and chronic kidney disease.1 passage
• The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT).1 passage
• The economic burden of physical inactivity: a global analysis of major non-communicable diseases.1 passage
• The effect of early, comprehensive genomic testing on clinical care in neonatal diabetes: an international cohort study.1 passage
• The effect of endotracheal tubes versus laryngeal mask airways on perioperative respiratory adverse events in infants: a randomised controlled trial.1 passage
• The effect of home-based care on housebound patients and their caregivers in two Palestinian refugee camps in Lebanon: a qualitative study.1 passage
• The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial.1 passage
• The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study.1 passage
• The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study.1 passage
• The effect of smoking on the healthy life expectancy of Palestinian men in the West Bank: a cross-sectional study.1 passage
• The effect of trauma on invasive group A streptococcal disease.1 passage
• The effectiveness of counselling interventions in reducing HbA1 passage
• The effects of armed conflict on the health of women and children.1 passage
• The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study.1 passage
• The escalating tuberculosis crisis in central and South American prisons.1 passage
• The ethics of the Global Kidney Exchange programme.1 passage
• The evolution of modern respiratory care for preterm infants.1 passage
• The evolution of the Italian National Health Service.1 passage
• The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications.1 passage
• The experience of family carers of children with incurable cancer: a qualitative study from the occupied Palestinian territory.1 passage
• The first and second waves of the COVID-19 pandemic in Africa: a cross-sectional study.1 passage
• The frequency of intrapartum caesarean section use with the WHO partograph versus Zhang's guideline in the Labour Progression Study (LaPS): a multicentre, cluster-randomised controlled trial.1 passage
• The frontotemporal dementia-motor neuron disease continuum.1 passage
• The future of atrial fibrillation management: integrated care and stratified therapy.1 passage
• The future of life expectancy and life expectancy inequalities in England and Wales: Bayesian spatiotemporal forecasting.1 passage
• The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013.1 passage
• The global burden of women's cancers: a grand challenge in global health.1 passage
• The global health law trilogy: towards a safer, healthier, and fairer world.1 passage
• The global response and unmet actions for HIV and sex workers.1 passage
• The global response to HIV in men who have sex with men.1 passage
• The health-systems response to violence against women.1 passage
• The heart and vascular system in dialysis.1 passage
• The heart of Africa: succeeding against the odds.1 passage
• The history, geography, and sociology of slums and the health problems of people who live in slums.1 passage
• The impact of e-health system implementation on UNWRA health services: an observational study.1 passage
• The influence of school in the development of eating disorders: a record-linkage study.1 passage
• The intersection between asthma and acute chest syndrome in children with sickle-cell anaemia.1 passage
• The inverse care law re-examined: a global perspective.1 passage
• The key role of palliative care in response to the COVID-19 tsunami of suffering.1 passage
• The link between kidney disease and cancer: complications and treatment.1 passage
• The magnitude of and health system responses to the mental health treatment gap in adults in India and China.1 passage
• The map is not the territory: medical records and 21st century practice.1 passage
• The metabolic stress response to burn trauma: current understanding and therapies.1 passage
• The motives, academic performance, and career prospects of Gazan medical students abroad: a cross-sectional study.1 passage
• The need for innovation and implementation research for maternal and newborn health.1 passage
• The need for transparency of clinical evidence for medical devices in Europe.1 passage
• The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study.1 passage
• The opioid crisis and HIV in the USA: deadly synergies.1 passage
• The overestimation and the inappropriate promotion of the benefits of mammographic screening in breast cancer research and interventions in the Gaza Strip.1 passage
• The past and future of haemophilia: diagnosis, treatments, and its complications.1 passage
• The path to eradication: a progress report on the malaria-eliminating countries.1 passage
• The path to longer and healthier lives for all Africans by 2030: the Lancet Commission on the future of health in sub-Saharan Africa.1 passage
• The pathogenesis of psoriatic arthritis.1 passage
• The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia.1 passage
• The persistent and evolving HIV epidemic in American men who have sex with men.1 passage
• The political and security dimensions of the humanitarian health response to violent conflict.1 passage
• The prevalence and risk factors of urinary incontinence among women with type 2 diabetes in the north West Bank: a cross-sectional study.1 passage
• The prevalence of diabetic peripheral neuropathy among diabetic Palestinian refugees in the Nuzha area, Jordan: a cross-sectional study.1 passage
• The primary health-care system in China.1 passage
• The protective role of maternal post-traumatic growth and cognitive trauma processing in Palestinian mothers and infants: a longitudinal study.1 passage
• The psychological impact of deprivation in regions affected by conflict: a multilevel analysis of a cross-sectional survey in the occupied Palestinian territory.1 passage
• The psychological impact of quarantine and how to reduce it: rapid review of the evidence.1 passage
• The public health control of scabies: priorities for research and action.1 passage
• The radiological evaluation process of the potential live kidney donor assessment programme at al-Shifa Hospital: study and clinical audit.1 passage
• The relation between health research output and burden of disease in Palestine: a systematic review.1 passage
• The relationships between democratic experience, adult health, and cause-specific mortality in 170 countries between 1980 and 2016: an observational analysis.1 passage
• The rise and fall of aspirin in the primary prevention of cardiovascular disease.1 passage
• The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis.1 passage
• The road to effective tobacco control in China.1 passage
• The role of BUB and CDC proteins in low-grade breast cancers.1 passage
• The role of facility-based surgical services in addressing the national burden of disease in New Zealand: an index of surgical incidence based on country-specific disease prevalence.1 passage
• The role of metalloproteinases and their tissue inhibitors in adipose tissue remodelling and whole-body lipid distribution: a cross-sectional clinical study.1 passage
• The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 study.1 passage
• The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.1 passage
• The scale, scope, coverage, and capability of childbirth care.1 passage
• The scale-up of the surgical workforce.1 passage
• The science of early adversity: is there a role for large institutions in the care of vulnerable children?1 passage
• The state of hypertension care in 44 low-income and middle-income countries: a cross-sectional study of nationally representative individual-level data from 1·1 million adults.1 passage
• The struggle for equity: an examination of surgical services at two NGO hospitals in rural Haiti.1 passage
• The war against heart failure: the Lancet lecture.1 passage
• Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.1 passage
• Therapeutics targeting the IL-23 and IL-17 pathway in psoriasis.1 passage
• Thin composite wire strut, durable polymer-coated (Resolute Onyx) versus ultrathin cobalt-chromium strut, bioresorbable polymer-coated (Orsiro) drug-eluting stents in allcomers with coronary artery disease (BIONYX): an international, single-blind, randomised non-inferiority trial.1 passage
• Three-dimensional visualisation of the fetal heart using prenatal MRI with motion-corrected slice-volume registration: a prospective, single-centre cohort study.1 passage
• Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis.1 passage
• Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial.1 passage
• Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate for men with lower urinary tract symptoms or urinary retention (UNBLOCS): a randomised controlled trial.1 passage
• Thyroid cancer.1 passage
• Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial.1 passage
• Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial.1 passage
• Ticagrelor versus clopidogrel in elective percutaneous coronary intervention (ALPHEUS): a randomised, open-label, phase 3b trial.1 passage
• Tildrakizumab versus placebo or etanercept for chronic plaque psoriasis (reSURFACE 1 and reSURFACE 2): results from two randomised controlled, phase 3 trials.1 passage
• Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial.1 passage
• Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial.1 passage
• Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.1 passage
• Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.1 passage
• Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial.1 passage
• Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial.1 passage
• Topical emollient for prevention of infection in preterm infants: a systematic review.1 passage
• Towards closing the gap of the global surgeon, anaesthesiologist, and obstetrician workforce: thresholds and projections towards 2030.1 passage
• Towards evidence-based resuscitation of the newborn infant.1 passage
• Towards universal civil registration and vital statistics systems: the time is now.1 passage
• Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050.1 passage
• Trajectories of childhood adversity and mortality in early adulthood: a population-based cohort study.1 passage
• Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.1 passage
• Transcatheter aortic valve replacement versus surgical valve replacement in intermediate-risk patients: a propensity score analysis.1 passage
• Transcatheter edge-to-edge repair for reduction of tricuspid regurgitation: 6-month outcomes of the TRILUMINATE single-arm study.1 passage
• Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme.1 passage
• Transfusion reactions: prevention, diagnosis, and treatment.1 passage
• Transgender people: health at the margins of society.1 passage
• Transition from acute to chronic pain after surgery.1 passage
• Transparency about the outcomes of mental health services (IAPT approach): an analysis of public data.1 passage
• Transport and public health in China: the road to a healthy future.1 passage
• Transvenous neurostimulation for central sleep apnoea: a randomised controlled trial.1 passage
• Trauma and orthopaedic capacity of 267 hospitals in east central and southern Africa.1 passage
• Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.1 passage
• Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial.1 passage
• Treatment of fibrotic interstitial lung disease: current approaches and future directions.1 passage
• Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study.1 passage
• Treatment of personality disorder.1 passage
• Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants.1 passage
• Trends in cause-specific mortality among adults with and without diagnosed diabetes in the USA: an epidemiological analysis of linked national survey and vital statistics data.1 passage
• Trends in cause-specific mortality among children aged 5-14 years from 2005 to 2016 in India, China, Brazil, and Mexico: an analysis of nationally representative mortality studies.1 passage
• Trends in future health financing and coverage: future health spending and universal health coverage in 188 countries, 2016-40.1 passage
• Trends in international asthma mortality: analysis of data from the WHO Mortality Database from 46 countries (1993-2012).1 passage
• Trends in premature mortality in the USA by sex, race, and ethnicity from 1999 to 2014: an analysis of death certificate data.1 passage
• Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.1 passage
• Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial.1 passage
• Tuberculosis in migrants moving from high-incidence to low-incidence countries: a population-based cohort study of 519 955 migrants screened before entry to England, Wales, and Northern Ireland.1 passage
• Tuberculosis.2 passages
• Tumour metabolism in squamous cell carcinoma of the head and neck: an in-vitro study of the consequences of TP53 mutation and therapeutic implications.1 passage
• Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial.1 passage
• Turning off the tap: stopping tuberculosis transmission through active case-finding and prompt effective treatment.1 passage
• Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, placebo-controlled trial.1 passage
• Type 1 diabetes.1 passage
• Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people.1 passage
• Type 2 diabetes in adolescents: a severe phenotype posing major clinical challenges and public health burden.1 passage
• Type 2 diabetes.1 passage
• Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence.1 passage
• Typhoid fever.1 passage
• UN political declaration on HIV and AIDS: where to begin?1 passage
• US Preventive Services Task Force recommendation statement regarding screening for peripheral artery disease with the ankle-brachial index: déjà vu all over again.1 passage
• Ulcerative colitis.1 passage
• Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial.1 passage
• Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 trial.1 passage
• Ultrasound guided transversus abdominis plane versus sham blocks after caesarean section in an Ugandan village hospital: a prospective, randomised, double-blinded, single-centre study.1 passage
• Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial.1 passage
• Ultrathin, bioresorbable polymer sirolimus-eluting stents versus thin, durable polymer everolimus-eluting stents in patients undergoing coronary revascularisation (BIOFLOW V): a randomised trial.1 passage
• Ultrathin-strut, biodegradable-polymer, sirolimus-eluting stents versus thin-strut, durable-polymer, everolimus-eluting stents for percutaneous coronary revascularisation: 5-year outcomes of the BIOSCIENCE randomised trial.1 passage
• Unacceptable failures: the final report of the Lancet Commission into liver disease in the UK.1 passage
• Understanding the mechanisms and drivers of antimicrobial resistance.1 passage
• Understanding the roles of faith-based health-care providers in Africa: review of the evidence with a focus on magnitude, reach, cost, and satisfaction.1 passage
• Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial.1 passage
• Unidirectional left-to-right interatrial shunting for treatment of patients with heart failure with reduced ejection fraction: a safety and proof-of-principle cohort study.1 passage
• Universal health coverage and intersectoral action for health: key messages from Disease Control Priorities, 3rd edition.1 passage
• Universal health coverage in Indonesia: concept, progress, and challenges.1 passage
• Universal health coverage in Latin American countries: how to improve solidarity-based schemes.1 passage
• Universal health coverage: breakthrough or great white elephant?1 passage
• Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes.1 passage
• Upadacitinib as monotherapy in patients with active rheumatoid arthritis and inadequate response to methotrexate (SELECT-MONOTHERAPY): a randomised, placebo-controlled, double-blind phase 3 study.1 passage
• Update on antithrombotic therapy after percutaneous coronary revascularisation.1 passage
• Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial.1 passage
• Urgent lessons from COVID 19: why the world needs a standing, coordinated system and sustainable financing for global research and development.1 passage
• Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study.1 passage
• Urinary tract infections in children.1 passage
• Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial.1 passage
• Use and definitions of perioperative mortality rates in low-income and middle-income countries: a systematic review.1 passage
• Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study.1 passage
• Use of a decision aid including information on overdetection to support informed choice about breast cancer screening: a randomised controlled trial.1 passage
• Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial.1 passage
• Use of and barriers to access to opioid analgesics: a worldwide, regional, and national study.1 passage
• Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.1 passage
• Use of effective contraception following provision of the progestogen-only pill for women presenting to community pharmacies for emergency contraception (Bridge-It): a pragmatic cluster-randomised crossover trial.1 passage
• Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa.1 passage
• Use of magnetic nanoparticles and oscillating magnetic field for non-viral gene transfer into mouse cornea.1 passage
• Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study.1 passage
• Use of renin-angiotensin-aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study.1 passage
• Use of science to guide city planning policy and practice: how to achieve healthy and sustainable future cities.1 passage
• Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial.1 passage
• Uses of polypills for cardiovascular disease and evidence to date.1 passage
• Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome: fevers, myalgia, arthralgia, auricular chondritis, and erythema nodosum.1 passage
• Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial.1 passage
• Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial.1 passage
• Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial.1 passage
• Validation of a community-based survey assessing non-obstetric surgical conditions in Burera District, Rwanda.1 passage
• Valvular aspects of rheumatic heart disease.1 passage
• Variability in mortality after caesarean delivery, appendectomy, and groin hernia repair in low-income and middle-income countries: implications for expanding surgical services.1 passage
• Variations between women and men in risk factors, treatments, cardiovascular disease incidence, and death in 27 high-income, middle-income, and low-income countries (PURE): a prospective cohort study.1 passage
• Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study.1 passage
• Vascular dementia.1 passage
• Venezuela's public health crisis: a regional emergency.1 passage
• Venezuelan migrants "struggling to survive" amid COVID-19.1 passage
• Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study.1 passage
• Venous thromboembolism.1 passage
• Very thin strut biodegradable polymer everolimus-eluting and sirolimus-eluting stents versus durable polymer zotarolimus-eluting stents in allcomers with coronary artery disease (BIO-RESORT): a three-arm, randomised, non-inferiority trial.1 passage
• Vesicoureteric reflux in children.1 passage
• Veverimer versus placebo in patients with metabolic acidosis associated with chronic kidney disease: a multicentre, randomised, double-blind, controlled, phase 3 trial.1 passage
• Viral bronchiolitis.1 passage
• Viral gastroenteritis.1 passage
• Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study.1 passage
• Visual outcomes associated with delay from trauma to surgery for open globe eye injury in Palestine: a retrospective chart review study.1 passage
• Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA): a pragmatic, open-label, randomised controlled trial.1 passage
• Vitiligo.1 passage
• Voluntary collective isolation as a best response to COVID-19 for indigenous populations? A case study and protocol from the Bolivian Amazon.1 passage
• Vulnerability to snakebite envenoming: a global mapping of hotspots.1 passage
• WHO launches crowdfund for COVID-19 response.1 passage
• WHO/International Society of Hypertension risk prediction charts versus the UK Prospective Diabetes Study risk engine for cardiovascular risk assessment among patients with type 2 diabetes: a comparative study.1 passage
• Waiting at the hospital door: a prospective, multicentre assessment of third delay in four tertiary hospitals in India.1 passage
• Weekend specialist intensity and admission mortality in acute hospital trusts in England: a cross-sectional study.1 passage
• Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal carcinoma treatment (ICON8): primary progression free survival analysis results from a GCIG phase 3 randomised controlled trial.1 passage
• Weekly variation in health-care quality by day and time of admission: a nationwide, registry-based, prospective cohort study of acute stroke care.1 passage
• Weight change between successive pregnancies and risks of stillbirth and infant mortality: a nationwide cohort study.1 passage
• Wellbeing, symptoms of trauma, and personal resources in Palestinian professional helpers: a cross-sectional quantitative survey.1 passage
• What are important outcomes of bariatric surgery? An in-depth analysis to inform the development of a core outcome set and a comparison between the views of surgeons and other health professionals (the BARIACT study).1 passage
• What does endotyping mean for treatment in chronic obstructive pulmonary disease?1 passage
• What is the private sector? Understanding private provision in the health systems of low-income and middle-income countries.1 passage
• What is the right level of spending needed for health and care in the UK?1 passage
• What low back pain is and why we need to pay attention.1 passage
• What will Donald Trump's presidency mean for health? A scorecard.1 passage
• What works in inclusion health: overview of effective interventions for marginalised and excluded populations.1 passage
• Where economics and epidemics collide: migrant workers and emerging infections.1 passage
• Which children and young people are excluded from school? Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC).1 passage
• Who is performing surgery in low-income settings: a countrywide inventory of the surgical workforce distribution and scope of practice in Sierra Leone.1 passage
• Who pays for cooperation in global health? A comparative analysis of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria, and Gavi, the Vaccine Alliance.1 passage
• Whole-exome sequencing in the evaluation of fetal structural anomalies: a prospective cohort study.1 passage
• Whole-population vision screening in children aged 4-5 years to detect amblyopia.1 passage
• Why do women choose or reject careers in academic medicine? A narrative review of empirical evidence.1 passage
• Why do women leave surgical training? A qualitative and feminist study.1 passage
• Why invest, and what it will take to improve breastfeeding practices?1 passage
• Why is WHO failing women with falciparum malaria in the first trimester of pregnancy?1 passage
• Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis.1 passage
• Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial.1 passage
• Working toward gender diversity and inclusion in medicine: myths and solutions.1 passage
• Worldwide access to treatment for end-stage kidney disease: a systematic review.1 passage
• Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.1 passage
• Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants.1 passage
• Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.1 passage
• Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants.1 passage
• Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.1 passage
• Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study.1 passage
• Zotarolimus-eluting durable-polymer-coated stent versus a biolimus-eluting biodegradable-polymer-coated stent in unselected patients undergoing percutaneous coronary intervention (SORT OUT VI): a randomised non-inferiority trial.1 passage
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• β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.1 passage