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1 passage

abstractpubmed· Abstract 2015· item PMID:25826542

Take my breath away: necrosis in kidney transplants kills the lungs! Necrosis is not only a regulated process, it is an interconnected molecular network allowing different genetically encoded forms that are more or less immunogenic. Zhao et al. elegantly illustrate this concept, underscore the need for combination therapy to successfully interfere with regulated necrosis, and identify the role of regulated necrosis in the pathophysiology of remote lung injury.