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abstractpubmed· Abstract 2016· item PMID:27312439
Phosphate enemas and GFR decline: it's premature to sound the alarm. Oral sodium phosphate solutions can cause acute phosphate nephropathy, resulting in acute kidney injury and chronic kidney disease. A recent cohort study suggests that phosphate enemas may also be associated with a decline in glomerular filtration rate, but further study is needed to establish a causal relationship.