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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• A Helicobacter pylori screening and treatment program to eliminate gastric cancer among junior high school students in Saga Prefecture: a preliminary report.1 passage
• A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis and anti-inflammatory response in inflammatory bowel disease.1 passage
• A case-control study of the risk of upper gastrointestinal mucosal injuries in patients prescribed concurrent NSAIDs and antithrombotic drugs based on data from the Japanese national claims database of 13 million accumulated patients.1 passage
• A cohort study on Helicobacter pylori infection associated with nonalcoholic fatty liver disease.1 passage
• A comparative study between sorafenib and hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis.1 passage
• A critical overview on the biological and molecular features of red and processed meat in colorectal carcinogenesis.1 passage
• A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia.1 passage
• A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk.1 passage
• A human gut ecosystem protects against C. difficile disease by targeting TcdA.1 passage
• A micro-RNA expression signature for human NAFLD progression.1 passage
• A multicenter observational study on the clinicopathological features of gastric cancer in young patients.1 passage
• A multicenter, retrospective, observational study of the clinical outcomes and risk factors for relapse of ulcerative colitis at 1 year after leukocytapheresis.1 passage
• A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea.1 passage
• A nationwide survey concerning the mortality and risk of progressing severity due to arterial and venous thromboembolism in inflammatory bowel disease in Japan.1 passage
• A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011-2015 update.1 passage
• A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease.1 passage
• A new era for understanding genetic evolution of multistep carcinogenesis.1 passage
• A novel method for screening colorectal cancer by infrared spectroscopy of peripheral blood mononuclear cells and plasma.1 passage
• A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial.1 passage
• A novel risk factor panel predicts early recurrence in resected pancreatic neuroendocrine tumors.1 passage
• A novel serum marker, glycosylated Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA(+)-M2BP), for assessing liver fibrosis.1 passage
• A novel urinary microRNA biomarker panel for detecting gastric cancer.1 passage
• A population-based study examining the risk of malignancy in patients diagnosed with inflammatory bowel disease.1 passage
• A possible involvement of endoplasmic reticulum stress in biliary epithelial autophagy and senescence in primary biliary cirrhosis.1 passage
• A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks.1 passage
• A proposed risk assessment score for gastrointestinal stromal tumors based on evaluation of 19,030 cases from the National Cancer Database.1 passage
• A proposed severity classification system for hepatolithiasis based on an analysis of prognostic factors in a Japanese patient cohort.1 passage
• A prospective, multicenter survey on the validity of shorter periendoscopic cessation of antithrombotic agents in Japan.1 passage
• A randomised, multicentre trial of somatostatin to prevent clinically relevant postoperative pancreatic fistula in intermediate-risk patients after pancreaticoduodenectomy.1 passage
• A randomized controlled trial of lusutrombopag in Japanese patients with chronic liver disease undergoing radiofrequency ablation.1 passage
• A scoring model for predicting advanced colorectal neoplasia in a screened population of asymptomatic Japanese individuals.1 passage
• A simple and practical index predicting the prognoses of the patients with well-differentiated pancreatic neuroendocrine neoplasms.1 passage
• A simple morphological classification to estimate the malignant potential of pancreatic neuroendocrine tumors.1 passage
• A simple prediction score for in-hospital mortality in patients with nonvariceal upper gastrointestinal bleeding.1 passage
• A simple scoring system using type IV collagen 7S and aspartate aminotransferase for diagnosing nonalcoholic steatohepatitis and related fibrosis.1 passage
• A single-arm, phase II trial of neoadjuvant gemcitabine and S1 in patients with resectable and borderline resectable pancreatic adenocarcinoma: PREP-01 study.1 passage
• A six-CpG panel with DNA methylation biomarkers predicting treatment response of chemoradiation in esophageal squamous cell carcinoma.1 passage
• A systematic review of the prevalence of germline pathogenic variants in patients with pancreatic cancer.1 passage
• A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus.1 passage
• ABCB4 mutations in adult patients with cholestatic liver disease: impact and phenotypic expression.1 passage
• ALEX1, a novel tumor suppressor gene, inhibits gastric cancer metastasis via the PAR-1/Rho GTPase signaling pathway.1 passage
• APC mutations are common in adenomas but infrequent in adenocarcinomas of the non-ampullary duodenum.1 passage
• Abdominal obesity increases risk for esophageal cancer: a nationwide population-based cohort study of South Korea.1 passage
• Aberrant BLM cytoplasmic expression associates with DNA damage stress and hypersensitivity to DNA-damaging agents in colorectal cancer.1 passage
• Accommodation in a refugee shelter as a risk factor for peptic ulcer bleeding after the Great East Japan Earthquake: a case-control study of 329 patients.1 passage
• Accuracy of liver stiffness measurement and controlled attenuation parameter using FibroScan1 passage
• Accurate and rapid identification of feeding arteries with multidetector-row angiography-assisted computed tomography for transarterial chemoembolization for hepatocellular carcinoma.1 passage
• Achalasia and esophageal cancer: a large database analysis in Japan.1 passage
• Achalasia symptom response after Heller myotomy segregated by high-resolution manometry subtypes.1 passage
• Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.1 passage
• Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma.1 passage
• Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis.1 passage
• Adhesion molecules and pancreatitis.1 passage
• Administration of a standard dose of vonoprazan fumarate delays gastric emptying in Japanese healthy adults: a prospective clinical trial.1 passage
• Adrenomedullin for steroid-resistant ulcerative colitis: a randomized, double-blind, placebo-controlled phase-2a clinical trial.1 passage
• Advances in the diagnosis and treatment of pancreatic neuroendocrine neoplasms in Japan.1 passage
• Adverse events in patients with ulcerative colitis treated with indigo naturalis: a Japanese nationwide survey.1 passage
• Adverse events of nucleos(t)ide analogues for chronic hepatitis B: a systematic review.1 passage
• Age at onset is associated with the seasonal pattern of onset and exacerbation in inflammatory bowel disease.1 passage
• Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science.1 passage
• Alteration of protein expression and spliceosome pathway activity during Barrett's carcinogenesis.1 passage
• An alternative option for "resect and discard" strategy, using magnifying narrow-band imaging: a prospective "proof-of-principle" study.1 passage
• An analysis of drug-induced liver injury, which showed histological findings similar to autoimmune hepatitis.1 passage
• An expert review on the use of tenofovir alafenamide for the treatment of chronic hepatitis B virus infection in Asia.1 passage
• An update on primary sclerosing cholangitis epidemiology, outcomes and quantification of alkaline phosphatase variability in a population-based cohort.1 passage
• Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease.1 passage
• Analysis of molecular alterations in laterally spreading tumors of the colorectum.1 passage
• Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease.1 passage
• Anti-ganglionic AChR antibodies in Japanese patients with motility disorders.1 passage
• Anti-tumor necrosis factor therapy decreases the risk of initial intestinal surgery after diagnosis of Crohn's disease of inflammatory type.1 passage
• Antibodies to Crohn's disease peptide 353 as a diagnostic marker for pediatric Crohn's disease: a prospective multicenter study in Japan.1 passage
• Antimicrobial proteins: intestinal guards to protect against liver disease.1 passage
• Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.1 passage
• Applicability of APRI and FIB-4 as a transition indicator of liver fibrosis in patients with chronic viral hepatitis.1 passage
• Application of transcutaneous ultrasonography for the diagnosis of muscle mass loss in patients with liver cirrhosis.1 passage
• Appropriate timing to start and optimal response evaluation of high-dose corticosteroid therapy for patients with acute liver failure.1 passage
• Appropriate use of virtual touch quantification and FibroScan M and XL probes according to the skin capsular distance.1 passage
• Artificial intelligence automates and augments baseline impedance measurements from pH-impedance studies in gastroesophageal reflux disease.1 passage
• Assessment of an electronic learning system for colon capsule endoscopy: a pilot study.1 passage
• Association between Wisteria floribunda agglutinin-positive Mac-2 binding protein and the fibrosis stage of non-alcoholic fatty liver disease.1 passage
• Association between alanine aminotransferase elevation and UGT1A1*6 polymorphisms in daclatasvir and asunaprevir combination therapy for chronic hepatitis C.1 passage
• Association between body size-metabolic phenotype and nonalcoholic steatohepatitis and significant fibrosis.1 passage
• Association between visceral abdominal obesity and long-segment Barrett's esophagus in a Japanese population.1 passage
• Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection.1 passage
• Autoimmune hepatitis in Japan: trends in a nationwide survey.1 passage
• Autoimmune pancreatitis complicated with inflammatory bowel disease and comparative study of type 1 and type 2 autoimmune pancreatitis.1 passage
• Automated cytological detection of Barrett's neoplasia with infrared spectroscopy.1 passage
• Basophils activated via TLR signaling may contribute to pathophysiology of type 1 autoimmune pancreatitis.1 passage
• Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa.1 passage
• Biliary carcinogenesis in pancreaticobiliary maljunction.1 passage
• Biochemical responses to bezafibrate improve long-term outcome in asymptomatic patients with primary biliary cirrhosis refractory to UDCA.1 passage
• Biphasic effect of alcohol intake on the development of fatty liver disease.1 passage
• Body mass index association with functional gastrointestinal disorders: differences between genders. Results from a study in a tertiary center.1 passage
• Bone morphogenetic protein 4 provides cancer-supportive phenotypes to liver fibroblasts in patients with hepatocellular carcinoma.1 passage
• Booster influenza vaccination does not improve immune response in adult inflammatory bowel disease patients treated with immunosuppressives: a randomized controlled trial.1 passage
• Bowel wall healing assessed using magnetic resonance imaging predicts sustained clinical remission and decreased risk of surgery in Crohn's disease.1 passage
• CCL19 enhances CD81 passage
• COVID-19-associated liver injury: from bedside to bench.1 passage
• CTNNB1 mutational analysis of solid-pseudopapillary neoplasms of the pancreas using endoscopic ultrasound-guided fine-needle aspiration and next-generation deep sequencing.1 passage
• Cabozantinib in Japanese patients with advanced hepatocellular carcinoma: a phase 2 multicenter study.1 passage
• Can serum albumin level affect the pharmacological action of tolvaptan in patients with liver cirrhosis? A post hoc analysis of previous clinical trials in Japan.1 passage
• Capsule endoscopy findings for the diagnosis of Crohn's disease: a nationwide case-control study.1 passage
• Carcinoembryonic antigen level in the pancreatic juice is effective in malignancy diagnosis and prediction of future malignant transformation of intraductal papillary mucinous neoplasm of the pancreas.1 passage
• Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications.1 passage
• Celiac disease in non-clinical populations of Japan.1 passage
• Celiac disease: from etiological factors to evolving diagnostic approaches.1 passage
• Characterization of fungal dysbiosis in Japanese patients with inflammatory bowel disease.1 passage
• Childhood abuse history is associated with the development of dyspepsia: a population-based survey in Japan.1 passage
• Chromosomal aneuploidies and combinational fluorescence in situ hybridization probe panels are useful for predicting prognosis for esophageal squamous cell carcinoma.1 passage
• Chronic inflammation with Helicobacter pylori infection is implicated in CD44 overexpression through miR-328 suppression in the gastric mucosa.1 passage
• Circular RNA TMEM87A promotes cell proliferation and metastasis of gastric cancer by elevating ULK1 via sponging miR-142-5p.1 passage
• Classification of patients with esophageal eosinophilia by patterns of sensitization revealed by a diagnostic assay for multiple allergen-specific IgEs.1 passage
• Clinical and microbiological features of infection in alcoholic hepatitis: an international cohort study.1 passage
• Clinical and pathophysiological aspects of type 1 autoimmune pancreatitis.1 passage
• Clinical benefits of neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreatic head: an observational study using inverse probability of treatment weighting.1 passage
• Clinical characteristics and molecular analysis of hepatitis B virus reactivation in hepatitis B surface antigen-negative patients during or after immunosuppressive or cytotoxic chemotherapy.1 passage
• Clinical characteristics, treatment, and prognosis of non-B, non-C hepatocellular carcinoma: a large retrospective multicenter cohort study.1 passage
• Clinical efficacy of intravenous doripenem in patients with acute biliary tract infection: a multicenter, randomized, controlled trial with imipenem/cilastatin as comparator.1 passage
• Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey.1 passage
• Clinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn's disease.1 passage
• Clinical guidelines for primary sclerosing cholangitis 2017.1 passage
• Clinical impact of different cut-off values in high-resolution manometry systems on diagnosing esophageal motility disorders.1 passage
• Clinical impact of intratumoral HER2 heterogeneity on trastuzumab efficacy in patients with HER2-positive gastric cancer.1 passage
• Clinical impact of sarcopenia assessment in patients with hepatocellular carcinoma undergoing treatments.1 passage
• Clinical impact of vonoprazan-based dual therapy with amoxicillin for H. pylori infection in a treatment-naïve cohort of junior high school students in Japan.1 passage
• Clinical importance of IL-22 cascade in IBD.1 passage
• Clinical importance of cine-MRI assessment of small bowel motility in patients with chronic intestinal pseudo-obstruction: a retrospective study of 33 patients.1 passage
• Clinical outcome of conservatively managed pancreatic intraductal papillary mucinous neoplasms with mural nodules and main duct dilation.1 passage
• Clinical outcomes and predictors for relapse after cessation of oral antiviral treatment in chronic hepatitis B patients.1 passage
• Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study).1 passage
• Clinical practice advice on lifestyle modification in the management of nonalcoholic fatty liver disease in Japan: an expert review.1 passage
• Clinical practice guideline for post-ERCP pancreatitis.1 passage
• Clinical relevance of esophageal subepithelial activity in eosinophilic esophagitis.1 passage
• Clinical significance of a papillary adenocarcinoma component in early gastric cancer: a single-center retrospective analysis of 628 surgically resected early gastric cancers.1 passage
• Clinical significance of hepatic steatosis according to coronary plaque morphology: assessment using controlled attenuation parameter.1 passage
• Clinical strategy of diagnosing and following patients with nonalcoholic fatty liver disease based on invasive and noninvasive methods.1 passage
• Clinical usefulness of endocytoscopy in the remission stage of ulcerative colitis: a pilot study.1 passage
• Clinicopathological and molecular correlations in traditional serrated adenoma.1 passage
• Clinicopathological characteristics and diagnostic performance of Wisteria floribunda agglutinin positive Mac-2-binding protein as a preoperative serum marker of liver fibrosis in hepatocellular carcinoma.1 passage
• Clinicopathological features and risk factors for lymph node metastasis in early-stage non-ampullary duodenal adenocarcinoma.1 passage
• Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.1 passage
• Combination of PNPLA3 and TLL1 polymorphism can predict advanced fibrosis in Japanese patients with nonalcoholic fatty liver disease.1 passage
• Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma.1 passage
• Combinational use of hepatitis B viral antigens predicts responses to nucleos(t)ide analogue/peg-interferon sequential therapy.1 passage
• Combinations of two drugs among NS3/4A inhibitors, NS5B inhibitors and non-selective antiviral agents are effective for hepatitis C virus with NS5A-P32 deletion in humanized-liver mice.1 passage
• Comorbidities and healthcare costs and resource use of patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) in the Japan medical data vision database.1 passage
• Comparison of gadoxetic acid-enhanced magnetic resonance imaging and contrast-enhanced computed tomography with histopathological examinations for the identification of hepatocellular carcinoma: a multicenter phase III study.1 passage
• Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice.1 passage
• Comparison of prognosis between observation and surgical resection groups with small sporadic non-functional pancreatic neuroendocrine neoplasms without distant metastasis.1 passage
• Comparison of propofol with midazolam in endoscopic submucosal dissection for esophageal squamous cell carcinoma: a randomized controlled trial.1 passage
• Comparison of three magnetic resonance enterography indices for grading activity in Crohn's disease.1 passage
• Comparison study of immunohistochemical staining for the diagnosis of type 1 autoimmune pancreatitis.1 passage
• Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study.1 passage
• Composite detection rate as an upper gastrointestinal endoscopy quality measure correlating with detection of neoplasia.1 passage
• Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.1 passage
• Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis.1 passage
• Comprehensive aptamer-based screen of 1317 proteins uncovers improved stool protein markers of colorectal cancer.1 passage
• Confounding factors of non-invasive tests for nonalcoholic fatty liver disease.1 passage
• Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort.1 passage
• Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model.1 passage
• Continuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial.1 passage
• Contribution of susceptibility variants at FCGR2A and 13q12 to the risk of relapse among Japanese patients with ulcerative colitis.1 passage
• Correlation between hypersensitivity induced by esophageal acid infusion and the baseline impedance level in patients with suspected gastroesophageal reflux.1 passage
• Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome.1 passage
• Cost-effectiveness analysis of lenvatinib treatment for patients with unresectable hepatocellular carcinoma (uHCC) compared with sorafenib in Japan.1 passage
• Cost-effectiveness of drug monitoring of anti-TNF therapy in inflammatory bowel disease and rheumatoid arthritis: a systematic review.1 passage
• Cost-utility analysis of a 'vonoprazan-first' strategy versus 'esomeprazole- or rabeprazole-first' strategy in GERD.1 passage
• Crohn's disease-specific mortality: a 30-year cohort study at a tertiary referral center in Japan.1 passage
• Cryptogenic cholestasis in young and adults: ATP8B1, ABCB11, ABCB4, and TJP2 gene variants analysis by high-throughput sequencing.1 passage
• Current and future pharmacological therapies for NAFLD/NASH.1 passage
• Current knowledge on non-steroidal anti-inflammatory drug-induced small-bowel damage: a comprehensive review.1 passage
• Current status of achalasia management: a review on diagnosis and treatment.1 passage
• Current status of preoperative biliary drainage.1 passage
• Cystic fibrosis transmembrane conductance regulator modulates enteric cholinergic activities and is abnormally expressed in the enteric ganglia of patients with slow transit constipation.1 passage
• Daclatasvir and asunaprevir in hemodialysis patients with hepatitis C virus infection: a nationwide retrospective study in Japan.1 passage
• Daclatasvir/asunaprevir/beclabuvir fixed-dose combination in Japanese patients with HCV genotype 1 infection.1 passage
• Deep sequencing analysis of quasispecies in the HBV pre-S region and its association with hepatocellular carcinoma.1 passage
• Defining the phenotype, pathogenesis and treatment of Crohn's disease associated spondyloarthritis.1 passage
• Detection of gastritis by a deep convolutional neural network from double-contrast upper gastrointestinal barium X-ray radiography.1 passage
• Detection of palisade vessels as a landmark for Barrett's esophagus in a Western population.1 passage
• Determining an optimal clinical dose of elobixibat, a novel inhibitor of the ileal bile acid transporter, in Japanese patients with chronic constipation: a phase II, multicenter, double-blind, placebo-controlled randomized clinical trial.1 passage
• Development and validation of a web-based questionnaire to identify environmental risk factors for inflammatory bowel disease: the Groningen IBD Environmental Questionnaire (GIEQ).1 passage
• Development of a scoring system for differentiating IgG4-related sclerosing cholangitis from primary sclerosing cholangitis.1 passage
• Diagnostic accuracy for macroscopic classification of nodular hepatocellular carcinoma: comparison of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging and angiography-assisted computed tomography.1 passage
• Diagnostic accuracy of combined biomarker measurements and vibration-controlled transient elastography (VCTE) for predicting fibrosis stage of non-alcoholic fatty liver disease.1 passage
• Diagnostic accuracy of demarcation of undifferentiated-type early gastric cancer after Helicobacter pylori eradication.1 passage
• Diagnostic efficacy of dual-focus endoscopy with narrow-band imaging using simplified dyad criteria for superficial esophageal squamous cell carcinoma.1 passage
• Diagnostic performance and factors influencing the accuracy of EUS-FNA of pancreatic neuroendocrine neoplasms.1 passage
• Diagnostic performance of magnifying endoscopy with narrow-band imaging in differentiating neoplastic colorectal polyps from non-neoplastic colorectal polyps: a meta-analysis.1 passage
• Diagnostic strategies for early pancreatic cancer.1 passage
• Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects.1 passage
• Differences in the risk of fatty liver for onset of impaired fasting glucose according to baseline plasma glucose levels.1 passage
• Different effects of dietary factors on reflux esophagitis and non-erosive reflux disease in 11,690 Korean subjects.1 passage
• Digital PCR-based plasma cell-free DNA mutation analysis for early-stage pancreatic tumor diagnosis and surveillance.1 passage
• Dihydropyrimidinase-like 3 is a putative hepatocellular carcinoma tumor suppressor.1 passage
• Direct-acting antivirals improve survival and recurrence rates after treatment of hepatocellular carcinoma within the Milan criteria.1 passage
• Distinct prognostic value of different portal hypertension-associated features in patients with primary biliary cholangitis.1 passage
• Distinguished prognosis after hepatectomy of HBV-related hepatocellular carcinoma with or without cirrhosis: a long-term follow-up analysis.1 passage
• Does the WHO 2010 classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas?1 passage
• Dose-response relationship between cigarette smoking and risk of ulcerative colitis: a nationwide population-based study.1 passage
• Dual red imaging (novel advanced endoscopy) can increase visibility and can predict the depth in diagnosing esophageal varices.1 passage
• Durable response without recurrence to Tolvaptan improves long-term survival.1 passage
• Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.1 passage
• Early gastric cancer with a mixed-type Lauren classification is more aggressive and exhibits greater lymph node metastasis.1 passage
• Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.1 passage
• Effect of branched-chain amino acid supplementation on functional liver regeneration in patients undergoing portal vein embolization and sequential hepatectomy: a randomized controlled trial.1 passage
• Effect of proton-pump inhibitors on the risk of lower gastrointestinal bleeding associated with NSAIDs, aspirin, clopidogrel, and warfarin.1 passage
• Effect of ramosetron in female patients with irritable bowel syndrome with diarrhea: a phase III long-term study.1 passage
• Effectiveness of adalimumab for the treatment of ulcerative colitis in clinical practice: comparison between anti-tumour necrosis factor-naïve and non-naïve patients.1 passage
• Effectiveness of tenofovir alafenamide for chronic hepatitis B patients with a poor response to the previously used nucleos(t)ide analogs.1 passage
• Effects of a novel endoscopic reporting system with voice recognition on the endoscopic procedure time and report preparation time: propensity score matching analysis.1 passage
• Effects of canagliflozin, an SGLT2 inhibitor, on hepatic function in Japanese patients with type 2 diabetes mellitus: pooled and subgroup analyses of clinical trials.1 passage
• Effects of proton pump inhibitor use on risk of Clostridium difficile infection: a hospital cohort study.1 passage
• Effects of vaccine-acquired polyclonal anti-HBs antibodies on the prevention of HBV infection of non-vaccine genotypes.1 passage
• Effects of vedolizumab in Japanese patients with Crohn's disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses.1 passage
• Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study.1 passage
• Efficacy and safety of daclatasvir and asunaprevir combination therapy in chronic hemodialysis patients with chronic hepatitis C.1 passage
• Efficacy and safety of glecaprevir and pibrentasvir treatment for 8 or 12 weeks in patients with recurrent hepatitis C after liver transplantation: a Japanese multicenter experience.1 passage
• Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection.1 passage
• Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis.1 passage
• Efficacy and safety of golimumab 52-week maintenance therapy in Japanese patients with moderate to severely active ulcerative colitis: a phase 3, double-blind, randomized, placebo-controlled study-(PURSUIT-J study).1 passage
• Efficacy and safety of hangeshashinto for treatment of GERD refractory to proton pump inhibitors : Usual dose proton pump inhibitors plus hangeshashinto versus double-dose proton pump inhibitors: randomized, multicenter open label exploratory study.1 passage
• Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study.1 passage
• Efficacy and safety of single fecal microbiota transplantation for Japanese patients with mild to moderately active ulcerative colitis.1 passage
• Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial.1 passage
• Efficacy and safety of twice-daily rabeprazole maintenance therapy for patients with reflux esophagitis refractory to standard once-daily proton pump inhibitor: the Japan-based EXTEND study.1 passage
• Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter randomised controlled trial.1 passage
• Efficacy of daclatasvir/asunaprevir according to resistance-associated variants in chronic hepatitis C with genotype 1.1 passage
• Efficacy of double-coated probiotics for irritable bowel syndrome: a randomized double-blind controlled trial.1 passage
• Efficacy of endoscopic ultrasound with artificial intelligence for the diagnosis of gastrointestinal stromal tumors.1 passage
• Efficacy of enteral nutrition in patients with Crohn's disease on maintenance anti-TNF-alpha antibody therapy: a meta-analysis.1 passage
• Efficacy of long-term tenofovir-based rescue therapy in patients with chronic hepatitis B refractory to nucleoside/nucleotide analogs.1 passage
• Efficacy of vonoprazan in prevention of bleeding from endoscopic submucosal dissection-induced gastric ulcers: a prospective randomized phase II study.1 passage
• Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase nucleotide inhibitor GS-558093 in human hepatocyte chimeric mice.1 passage
• Emerging biologics in inflammatory bowel disease.1 passage
• Emerging role and therapeutic application of exosome in hepatitis virus infection and associated diseases.1 passage
• Emerging therapies for PBC.1 passage
• Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities.1 passage
• Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey.1 passage
• Endoscopic diagnosis and treatment of esophageal adenocarcinoma: introduction of Japan Esophageal Society classification of Barrett's esophagus.1 passage
• Endoscopic diagnosis of hiatus hernia under deep inspiration is not consistent with esophageal manometric diagnosis.1 passage
• Endoscopic ultrasonography assessment of para-esophageal varices predicts efficacy of propranolol in preventing recurrence of esophageal varices.1 passage
• Enhanced endoscopic detection of occult gastric cancer in carriers of pathogenic CDH1 variants.1 passage
• Environmental factors, medical and family history, and comorbidities associated with primary biliary cholangitis in Japan: a multicenter case-control study.1 passage
• Eosinophilic esophagitis: novel concepts regarding pathogenesis and clinical manifestations.1 passage
• Epidemiologic features of 348 children with hepatitis C virus infection over a 30-year period: a nationwide survey in Japan.1 passage
• Epidemiological analysis of achalasia in Japan using a large-scale claims database.1 passage
• Epidemiological trends of pancreatic and gastrointestinal neuroendocrine tumors in Japan: a nationwide survey analysis.1 passage
• Epithelial barrier dysfunction in lymphocytic colitis through cytokine-dependent internalization of claudin-5 and -8.1 passage
• Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis.1 passage
• Epithelial-stromal crosstalk and fibrosis in eosinophilic esophagitis.1 passage
• Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping.1 passage
• Epstein-Barr virus status is a promising biomarker for endoscopic resection in early gastric cancer: proposal of a novel therapeutic strategy.1 passage
• Esophageal cancer stem cells are suppressed by tranilast, a TRPV2 channel inhibitor.1 passage
• Esophageal motility after peroral endoscopic myotomy for achalasia.1 passage
• Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology.1 passage
• Esophagectomy for superficial esophageal cancer after non-curative endoscopic resection.1 passage
• Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids.1 passage
• Estimated prevalence of ulcerative colitis and Crohn's disease in Japan in 2014: an analysis of a nationwide survey.1 passage
• Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease.1 passage
• Evaluation of inflammation-based prognostic scores in patients undergoing hepatobiliary resection for perihilar cholangiocarcinoma.1 passage
• Evaluation of serum HER2-ECD levels in patients with gastric cancer.1 passage
• Evaluation of the efficacy of peritoneal lavage with distilled water in colorectal cancer surgery: in vitro and in vivo study.1 passage
• Evaluation of the risk factors associated with rectal neuroendocrine tumors: a big data analytic study from a health screening center.1 passage
• Evidence-based clinical practice guidelines for Liver Cirrhosis 2020.1 passage
• Evidence-based clinical practice guidelines for cholelithiasis 2016.1 passage
• Evidence-based clinical practice guidelines for chronic pancreatitis 2015.1 passage
• Evidence-based clinical practice guidelines for functional dyspepsia.1 passage
• Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015.1 passage
• Evidence-based clinical practice guidelines for inflammatory bowel disease 2020.1 passage
• Evidence-based clinical practice guidelines for inflammatory bowel disease.1 passage
• Evidence-based clinical practice guidelines for irritable bowel syndrome 2020.1 passage
• Evidence-based clinical practice guidelines for irritable bowel syndrome.1 passage
• Evidence-based clinical practice guidelines for liver cirrhosis 2015.1 passage
• Evidence-based clinical practice guidelines for management of colorectal polyps.2 passages
• Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020.1 passage
• Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.1 passage
• Evidence-based clinical practice guidelines for peptic ulcer disease 2015.1 passage
• Evidence-based clinical practice guidelines for peptic ulcer disease 2020.1 passage
• Evidence-based diagnosis and clinical practice guidelines for intestinal Behçet's disease 2020 edited by Intractable Diseases, the Health and Labour Sciences Research Grants.1 passage
• Excellent prognosis following endoscopic resection of patients with rectal neuroendocrine tumors despite the frequent presence of lymphovascular invasion.1 passage
• Excessive risk of second-cancer incidence and cancer mortality in patients with esophageal cancer.1 passage
• Expanding endoscopic interventions for pancreatic pseudocyst and walled-off necrosis.1 passage
• Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia.1 passage
• Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors.1 passage
• Factors affecting in-hospital mortality in patients with lower gastrointestinal tract bleeding: a retrospective study using a national database in Japan.1 passage
• Factors affecting recurrence and prognosis after R0 resection for colorectal cancer with peritoneal metastasis.1 passage
• Factors affecting response to proton pump inhibitor therapy in patients with gastroesophageal reflux disease: a multicenter prospective observational study.1 passage
• Factors associated with delayed hemorrhage after endoscopic sphincterotomy: Japanese large single-center experience.1 passage
• Factors associated with exacerbation of newly diagnosed mild ulcerative colitis based on a nationwide registry in Japan.1 passage
• Factors associated with poor therapeutic response in outpatients with irritable bowel syndrome: a multicenter study in Japan.1 passage
• Familial pancreatic cancer risk: a population-based study in Utah.1 passage
• Fatty acid-driven modifications in T-cell profiles in non-alcoholic fatty liver disease patients.1 passage
• Feasibility of a simplified narrow-band imaging classification system for Barrett's esophagus for novice endoscopists.1 passage
• Fecal calprotectin: its scope and utility in the management of inflammatory bowel disease.1 passage
• Fecal microbiota transplantation and Clostridioides difficile infection among privately insured patients in the United States.1 passage
• First trough level of infliximab at week 2 predicts future outcomes of induction therapy in ulcerative colitis-results from a multicenter prospective randomized controlled trial and its post hoc analysis.1 passage
• Fluid sequestration is a useful parameter in the early identification of severe disease of acute pancreatitis.1 passage
• Food antigen-induced immune responses in Crohn's disease patients and experimental colitis mice.1 passage
• Four-year maintenance treatment with adalimumab in Japanese patients with moderately to severely active ulcerative colitis.1 passage
• Functional lumen imaging of the gastrointestinal tract.1 passage
• Fusobacterium nucleatum as a prognostic marker of colorectal cancer in a Japanese population.1 passage
• Gastric atrophy and xanthelasma are markers for predicting the development of early gastric cancer.1 passage
• Gastric cancer stem cells: evidence, potential markers, and clinical implications.1 passage
• Gastric epithelial neoplasm of fundic-gland mucosa lineage: proposal for a new classification in association with gastric adenocarcinoma of fundic-gland type.1 passage
• Gastrointestinal endoscopy in patients receiving novel direct oral anticoagulants: results from the prospective Dresden NOAC registry.1 passage
• Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey.1 passage
• Gastrointestinal mucosal barrier function and diseases.1 passage
• Gastrointestinal stromal tumors in Japanese patients with neurofibromatosis type I.1 passage
• Gender difference in the overlap of irritable bowel syndrome and functional dyspepsia: a prospective nationwide multicenter study in Korea.1 passage
• Genetic basis of hepatitis virus-associated hepatocellular carcinoma: linkage between infection, inflammation, and tumorigenesis.1 passage
• Genetic characteristics of inflammatory bowel disease in a Japanese population.1 passage
• Genetic variants in RPA1 associated with the response to oxaliplatin-based chemotherapy in colorectal cancer.1 passage
• Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X.1 passage
• Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy.1 passage
• Geoepidemiology and changing mortality in primary biliary cholangitis.1 passage
• Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines.1 passage
• Gut microbiome diversity in acute infective and chronic inflammatory gastrointestinal diseases in North India.1 passage
• Gut microbiota and the development of pediatric diseases.1 passage
• Gut microbiota dysbiosis worsens the severity of acute pancreatitis in patients and mice.1 passage
• HBeAg-positive patients with HBsAg  < 100 IU/mL and negative HBV RNA have lower risk of virological relapse after nucleos(t)ide analogues cessation.1 passage
• Helicobacter pylori infection causes hepatic insulin resistance by the c-Jun/miR-203/SOCS3 signaling pathway.1 passage
• Helicobacter pylori infection might have a potential role in hepatocyte ballooning in nonalcoholic fatty liver disease.1 passage
• Helicobacter pylori status and risks of metachronous recurrence after endoscopic resection of early gastric cancer: a systematic review and meta-analysis.1 passage
• Hemodynamic effect of the left gastric artery on esophageal varices in patients with cirrhosis.1 passage
• Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients.1 passage
• Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients.1 passage
• Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights.1 passage
• Hepatitis B surface antigen seroclearance during nucleoside analogue therapy: surface antigen kinetics, outcomes, and durability.1 passage
• Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients.1 passage
• Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan.1 passage
• Hepatocellular carcinoma in Japanese patients with nonalcoholic fatty liver disease and alcoholic liver disease: multicenter survey.1 passage
• Heterogeneity in endoscopic treatment of Crohn's disease-associated strictures: An international inflammatory bowel disease specialist survey.1 passage
• High incidence of head and neck cancers after endoscopic resection for esophageal cancer in younger patients.1 passage
• High levels of serum Mac-2-binding protein glycosylation isomer (M2BPGi) predict the development of hepatocellular carcinoma in hepatitis B patients treated with nucleot(s)ide analogues.1 passage
• High-resolution melt analysis enables simple genotyping of complicated polymorphisms of codon 18 rendering the NUDT15 diplotype.1 passage
• High-throughput screening identified miR-7-2-3p and miR-29c-3p as metastasis suppressors in gallbladder carcinoma.1 passage
• Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer.1 passage
• Host-virus interactions in hepatitis B and hepatitis C infection.1 passage
• How long should patients be surveyed for gastric cancer risk after Helicobacter pylori eradication therapy? 10 years is no longer enough.1 passage
• Human hepatic stellate cell isolation and characterization.1 passage
• IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis.1 passage
• ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.1 passage
• Identification of a high-risk group for low-dose aspirin-induced gastropathy by measuring serum pepsinogen in H. pylori-infected subjects.1 passage
• Identification of a serum transglutaminase threshold value for the noninvasive diagnosis of symptomatic adult celiac disease patients: a retrospective study.1 passage
• Identification of differentially expressed signatures of long non-coding RNAs associated with different metastatic potentials in gastric cancer.1 passage
• Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas.1 passage
• IgG4-related sclerosing cholangitis: all we need to know.1 passage
• Image assessment of Barrett's esophagus using the simplified narrow band imaging classification.1 passage
• Immunoglobulin A and liver diseases.1 passage
• Impact of acute kidney injury on prognosis and the effect of tolvaptan in patients with hepatic ascites.1 passage
• Impact of alpha-fetoprotein on hepatocellular carcinoma development during entecavir treatment of chronic hepatitis B virus infection.1 passage
• Impact of continuous regional arterial infusion in the treatment of acute necrotizing pancreatitis: analysis of a national administrative database.1 passage
• Impact of endoscopic ultrasonography on diagnosis of pancreatic cancer.1 passage
• Impact of inflammatory bowel disease on Japanese patients' quality of life: results of a patient questionnaire survey.1 passage
• Impact of sustained virological response with DAAs on gastroesophageal varices and Baveno criteria in HCV-cirrhotic patients.1 passage
• Impact of the Charlson Comorbidity Index on the treatment strategy and survival in elderly patients after non-curative endoscopic submucosal dissection for esophageal squamous cell carcinoma: a multicenter retrospective study.1 passage
• Impact of tumor localization on the outcomes of surgery for an intrahepatic cholangiocarcinoma.1 passage
• Impairment of chemical clearance and mucosal integrity distinguishes hypersensitive esophagus from functional heartburn.1 passage
• Incidence and clinical outcomes of intestinal Behçet's disease in Korea, 2011-2014: a nationwide population-based study.1 passage
• Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study.1 passage
• Increase in plasma acyl ghrelin levels is associated with abatement of dyspepsia following Helicobacter pylori eradication.1 passage
• Increase in the skeletal muscle mass to body fat mass ratio predicts the decline in transaminase in patients with nonalcoholic fatty liver disease.1 passage
• Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation.1 passage
• Increased IL-17A/IL-17F expression ratio represents the key mucosal T helper/regulatory cell-related gene signature paralleling disease activity in ulcerative colitis.1 passage
• Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn's disease is a risk factor for disease relapse in Japanese patients.1 passage
• Increased expression of PHD3 represses the HIF-1 signaling pathway and contributes to poor neovascularization in pancreatic ductal adenocarcinoma.1 passage
• Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma.1 passage
• Independent association between prediabetes and future pancreatic fat accumulation: a 5-year Japanese cohort study.1 passage
• Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study.1 passage
• Indole compounds may be promising medicines for ulcerative colitis.1 passage
• Induction of PIR-A/B1 passage
• Infectious complications and timing for liver transplantation in autoimmune acute liver failure in Japan: a subanalysis based on nationwide surveys between 2010 and 2015.1 passage
• Influence of previous abdominal surgery on surgical outcomes between laparoscopic and open surgery in elderly patients with colorectal cancer: subanalysis of a large multicenter study in Japan.1 passage
• Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.1 passage
• Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections.1 passage
• Insulin receptor substrate-4 is overexpressed in colorectal cancer and promotes retinoblastoma-cyclin-dependent kinase activation.1 passage
• Insulin secretion improvement during steroid therapy for autoimmune pancreatitis according to the onset of diabetes mellitus.1 passage
• Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection.1 passage
• Integrated analysis of circRNAs and mRNAs expression profile revealed the involvement of hsa_circ_0007919 in the pathogenesis of ulcerative colitis.1 passage
• Interleukin-35 promotes the differentiation of regulatory T cells and suppresses Th2 response in IgG4-related type 1 autoimmune pancreatitis.1 passage
• Internet survey on the actual situation of constipation in the Japanese population under 70 years old: focus on functional constipation and constipation-predominant irritable bowel syndrome.1 passage
• Intestinal and hepatic drug transporters: pharmacokinetic, pathophysiological, and pharmacogenetic roles.1 passage
• Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives.1 passage
• Intestinal stem cell transplantation.1 passage
• Intestine-specific homeobox (ISX) induces intestinal metaplasia and cell proliferation to contribute to gastric carcinogenesis.1 passage
• Invariant natural killer T cell deficiency leads to the development of spontaneous liver inflammation dependent on γδT cells in mice.1 passage
• Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.1 passage
• Involvement of epithelial to mesenchymal transition in the development of pancreatic ductal adenocarcinoma.1 passage
• Involvement of herbal medicine as a cause of mesenteric phlebosclerosis: results from a large-scale nationwide survey.1 passage
• Is a fecal occult blood test a useful tool for judging whether to perform capsule endoscopy in low-dose aspirin users with negative colonoscopy and esophagogastroduodenoscopy?1 passage
• Is patient-reported outcome improved by nalfurafine hydrochloride in patients with primary biliary cholangitis and refractory pruritus? A post-marketing, single-arm, prospective study.1 passage
• Is radical surgery necessary in all patients who do not meet the curative criteria for endoscopic submucosal dissection in early gastric cancer? A multi-center retrospective study in Japan.1 passage
• Is the incidence of esophageal adenocarcinoma increasing in Japan? Trends from the data of a hospital-based registration system in Akita Prefecture, Japan.1 passage
• Is the new potent acid-inhibitory drug vonoprazan effective for healing idiopathic peptic ulcers? A multicenter observational study in Akita Prefecture, Japan.1 passage
• JNETS clinical practice guidelines for gastroenteropancreatic neuroendocrine neoplasms: diagnosis, treatment, and follow-up: a synopsis.1 passage
• JNJ-4178 (adafosbuvir, odalasvir, and simeprevir) in Japanese patients with chronic hepatitis C virus genotype 1 or 2 infection with or without compensated cirrhosis: the Phase IIa OMEGA-3 study.1 passage
• Kupffer phase image of Sonazoid-enhanced US is useful in predicting a hypervascularization of non-hypervascular hypointense hepatic lesions detected on Gd-EOB-DTPA-enhanced MRI: a multicenter retrospective study.1 passage
• Laparoscopic surgery for colorectal cancer is safe and has survival outcomes similar to those of open surgery in elderly patients with a poor performance status: subanalysis of a large multicenter case-control study in Japan.1 passage
• Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study.1 passage
• Linked color imaging can enhance recognition of early gastric cancer by high color contrast to surrounding gastric intestinal metaplasia.1 passage
• Liver disease in adults with severe alpha-1-antitrypsin deficiency.1 passage
• Long-term natural history of liver disease in patients with chronic hepatitis B virus infection: an analysis using the Markov chain model.1 passage
• Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan.1 passage
• Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group.1 passage
• Long-term outcomes after treatment for pedunculated-type T1 colorectal carcinoma: a multicenter retrospective cohort study.1 passage
• Long-term prognosis of patients with chronic hepatitis C who did not receive interferon-based therapy: causes of death and analysis based on the FIB-4 index.1 passage
• Long-term prognosis of patients with hepatitis B infection: causes of death and utility of nucleos(t)ide analogue therapy.1 passage
• Long-term proton pump inhibitor usage and the association with pancreatic cancer in Sweden.1 passage
• Longitudinal association of fatty pancreas with the incidence of type-2 diabetes in lean individuals: a 6-year computed tomography-based cohort study.1 passage
• Low alcohol consumption increases the risk of impaired glucose tolerance in patients with non-alcoholic fatty liver disease.1 passage
• Low-dose maintenance steroid treatment could reduce the relapse rate in patients with type 1 autoimmune pancreatitis: a long-term Japanese multicenter analysis of 510 patients.1 passage
• Lower body mass index predicts worse cancer-specific prognosis in octogenarians with colorectal cancer.1 passage
• MICA SNPs and the NKG2D system in virus-induced HCC.1 passage
• Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis.1 passage
• Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs.1 passage
• Magnetic resonance evaluation for small bowel strictures in Crohn's disease: comparison with balloon enteroscopy.1 passage
• Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and meta-analysis.1 passage
• Management and outcome of gastrointestinal bleeding in patients taking oral anticoagulants or antiplatelet drugs.1 passage
• Management of elderly ulcerative colitis in Japan.1 passage
• Management of low-dose aspirin and clopidogrel in clinical practice: a gastrointestinal perspective.1 passage
• Management of refractory ascites attenuates muscle mass reduction and improves survival in patients with decompensated cirrhosis.1 passage
• Manipulating resident microbiota to enhance regulatory immune function to treat inflammatory bowel diseases.1 passage
• Marked impact of tumor location on the appropriate cutoff values and the prognostic significance of the lymph node ratio in stage III colon cancer: a multi-institutional retrospective analysis.1 passage
• Medical costs according to the stages of colorectal cancer: an analysis of health insurance claims in Hachioji, Japan.1 passage
• Mesenchymal stem cell therapy for acute and chronic pancreatitis.1 passage
• Meta-analysis: proton pump inhibitors moderately increase the risk of small intestinal bacterial overgrowth.1 passage
• Microbial biomarkers for immune checkpoint blockade therapy against cancer.1 passage
• Microbial mucosal colonic shifts associated with the development of colorectal cancer reveal the presence of different bacterial and archaeal biomarkers.1 passage
• Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases.1 passage
• Microinflammation in the intestinal mucosa and symptoms of irritable bowel syndrome.1 passage
• Microsatellite instability and immune checkpoint inhibitors: toward precision medicine against gastrointestinal and hepatobiliary cancers.1 passage
• Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice.1 passage
• Modifiable factors and esophageal cancer: a systematic review of published meta-analyses.1 passage
• Molecular alterations in colorectal adenomas and intramucosal adenocarcinomas defined by high-density single-nucleotide polymorphism arrays.1 passage
• Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study).1 passage
• Molecular mechanisms of pancreatic myofibroblast activation in chronic pancreatitis and pancreatic ductal adenocarcinoma.1 passage
• Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis.1 passage
• Molecular subtype switching in early-stage gastric cancers with multiple occurrences.1 passage
• More severe upper gastrointestinal symptoms associated with non-erosive reflux disease than with erosive gastroesophageal reflux disease during maintenance proton pump inhibitor therapy.1 passage
• Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras.1 passage
• Mucosal IL23A expression predicts the response to Ustekinumab in inflammatory bowel disease.1 passage
• Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis.1 passage
• Multi-regional sequencing reveals clonal and polyclonal seeding from primary tumor to metastases in advanced gastric cancer.1 passage
• Multicenter observational study on functional bowel disorders diagnosed using Rome III diagnostic criteria in Japan.1 passage
• Multicenter prospective in vivo study of an endocytoscope system (ECS) for superficial esophageal cancer.1 passage
• Multicenter, cross-sectional, observational study on Epstein-Barr viral infection status and thiopurine use by age group in patients with inflammatory bowel disease in Japan (EBISU study).1 passage
• Muscle atrophy as pre-sarcopenia in Japanese patients with chronic liver disease: computed tomography is useful for evaluation.1 passage
• NS5A resistance-associated variants undermine the effectiveness of ledipasvir and sofosbuvir for cirrhotic patients infected with HCV genotype 1b.1 passage
• NS5A-P32 deletion as a factor involved in virologic failure in patients receiving glecaprevir and pibrentasvir.1 passage
• NSAID enteropathy and bacteria: a complicated relationship.1 passage
• NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease.1 passage
• NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.1 passage
• NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers.1 passage
• Nationwide epidemiological survey of autoimmune pancreatitis in Japan in 2016.1 passage
• Nationwide epidemiological survey of chronic pancreatitis in Japan: introduction and validation of the new Japanese diagnostic criteria 2019.1 passage
• Nationwide epidemiological survey of early chronic pancreatitis in Japan.1 passage
• Nationwide prospective and retrospective surveys for hepatitis B virus reactivation during immunosuppressive therapies.1 passage
• Nationwide survey for acute liver failure and late-onset hepatic failure in Japan.1 passage
• Nationwide survey for patients with acute-on-chronic liver failure occurring between 2017 and 2019 and diagnosed according to proposed Japanese criteria.1 passage
• Nationwide survey of hereditary pancreatitis in Japan.1 passage
• Nationwide survey of neuroendocrine carcinoma of the esophagus: a multicenter study conducted among institutions accredited by the Japan Esophageal Society.1 passage
• Natural history of asymptomatic bile duct stones and association of endoscopic treatment with clinical outcomes.1 passage
• Natural history of chronic hepatitis B virus infection in children in Japan: a comparison of mother-to-child transmission with horizontal transmission.1 passage
• Near-focus magnification and second-generation narrow-band imaging for early gastric cancer in a randomized trial.1 passage
• New endoscopic classification of cascade stomach, a risk factor for reflux esophagitis.1 passage
• New resistance-associated substitutions and failure of dual oral therapy with daclatasvir and asunaprevir.1 passage
• New treatment options for inflammatory bowel diseases.1 passage
• New-generation narrow band imaging improves visibility of polyps: a colonoscopy video evaluation study.1 passage
• No increase in gastric acid secretion in healthy Japanese over the past two decades.1 passage
• No weekend effect on outcomes of severe acute pancreatitis in Japan: data from the diagnosis procedure combination database.1 passage
• Non-nucleoside hepatitis B virus polymerase inhibitors identified by an in vitro polymerase elongation assay.1 passage
• Nonalcoholic fatty liver disease in Asia: emerging perspectives.1 passage
• Nonalcoholic fatty liver disease is associated with lower hepatitis B viral load and antiviral response in pediatric population.1 passage
• Nonalcoholic fatty liver disease: impact on healthcare resource utilization, liver transplantation and mortality in a large, integrated healthcare system.1 passage
• Noninvasive diagnostic criteria for nonalcoholic steatohepatitis based on gene expression levels in peripheral blood mononuclear cells.1 passage
• Novel and highly sensitive immunoassay for total hepatitis B surface antigen, including that complexed with hepatitis B surface antibody.1 passage
• Obesity with abundant subcutaneous adipose tissue increases the risk of post-ERCP pancreatitis.1 passage
• Obesity-related parameters and colorectal adenoma development.1 passage
• Objective evaluation for treat to target in Crohn's disease.1 passage
• Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage.1 passage
• Operative and medical treatment of chronic anal fissures-a review and network meta-analysis of randomized controlled trials.1 passage
• Optimal cutoff value of integrated relaxation pressure on the esophagogastric junction to detect outflow obstruction using starlet high-resolution manometry system.1 passage
• Oral administration of D-serine prevents the onset and progression of colitis in mice.1 passage
• Oral branched-chain amino acid granules improve structure and function of human serum albumin in cirrhotic patients.1 passage
• Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab.1 passage
• Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells.1 passage
• PKD signaling and pancreatitis.1 passage
• PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication.1 passage
• Pancreatic cancer arising from the remnant pancreas after pancreatectomy: a multicenter retrospective study by the Kyushu Study Group of Clinical Cancer.1 passage
• Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion.1 passage
• Pancreatic cysts in general population on ultrasonography: Prevalence and development of risk score.1 passage
• Pancreaticobiliary maljunction and biliary cancer.1 passage
• Pancrelipase with branched-chain amino acids for preventing nonalcoholic fatty liver disease after pancreaticoduodenectomy.1 passage
• Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.1 passage
• Pathological risk factors and predictive endoscopic factors for lymph node metastasis of T1 colorectal cancer: a single-center study of 846 lesions.1 passage
• Patients with dyspepsia have impaired mucosal integrity both in the duodenum and jejunum: in vivo assessment of small bowel mucosal integrity using baseline impedance.1 passage
• Percutaneous biliary drainage is oncologically inferior to endoscopic drainage: a propensity score matching analysis in resectable distal cholangiocarcinoma.1 passage
• Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma: a randomized double-blind placebo-controlled study.1 passage
• Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping.1 passage
• Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma.1 passage
• Physician-patient communication affects patient satisfaction in treatment decision-making: a structural equation modelling analysis of a web-based survey in patients with ulcerative colitis.1 passage
• Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B.1 passage
• Polyethylene glycol 3350 plus electrolytes for chronic constipation: a 2-week, randomized, double-blind, placebo-controlled study with a 52-week open-label extension.1 passage
• Possible involvement of Toll-like receptor 7 in the development of type 1 autoimmune pancreatitis.1 passage
• Post-reflux swallow-induced peristaltic wave (PSPW): physiology, triggering factors and role in reflux clearance in healthy subjects.1 passage
• Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma.1 passage
• Postoperative prognosis of pancreatic cancer with para-aortic lymph node metastasis: a multicenter study on 822 patients.1 passage
• Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.1 passage
• Potential roles of gastroesophageal reflux in patients with superficial esophageal squamous cell carcinoma without major causative risk factors.1 passage
• Pouch functional outcomes after restorative proctocolectomy with ileal-pouch reconstruction in patients with ulcerative colitis: Japanese multi-center nationwide cohort study.1 passage
• Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis.1 passage
• Prediction of development of hepatocellular carcinoma using a new scoring system involving virtual touch quantification in patients with chronic liver diseases.1 passage
• Predictive factors of the pharmacological action of tolvaptan in patients with liver cirrhosis: a post hoc analysis.1 passage
• Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy.1 passage
• Predictive value of serum HER2 ECD in patients with HER2-positive advanced gastric cancer treated with trastuzumab plus chemotherapy.1 passage
• Prevalence and predictors of small intestinal bacterial overgrowth in irritable bowel syndrome: a systematic review and meta-analysis.1 passage
• Prevalence and risk factors for lymph node metastasis after noncurative endoscopic resection for early gastric cancer: a systematic review and meta-analysis.1 passage
• Prevalence of and risk factors for non-alcoholic fatty liver disease in a non-obese Japanese population, 2011-2012.1 passage
• Prevalence of behavioral disorders in patients with vonoprazan-refractory reflux symptoms.1 passage
• Prevalence of nonalcoholic steatohepatitis in Japanese patients with morbid obesity undergoing bariatric surgery.1 passage
• Prevention of delayed bleeding with vonoprazan in upper gastrointestinal endoscopic treatment.1 passage
• Procalcitonin is a useful biomarker to predict severe acute cholangitis: a single-center prospective study.1 passage
• Profiling of circulating microRNAs in patients with Barrett's esophagus and esophageal adenocarcinoma.1 passage
• Prognostic impact of PD-L1 expression in primary gastric and intestinal diffuse large B-cell lymphoma.1 passage
• Prognostic impact of primary tumor location in Stage III colorectal cancer-right-sided colon versus left-sided colon versus rectum: a nationwide multicenter retrospective study.1 passage
• Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy.1 passage
• Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer.1 passage
• Prospective evaluation of endoscopic criteria characteristic of sessile serrated adenomas/polyps.1 passage
• Prospective randomized study of endoscopic biliary stone extraction using either a basket or a balloon catheter: the BasketBall study.1 passage
• Prospective study of early chronic pancreatitis diagnosed based on the Japanese diagnostic criteria.1 passage
• Proteomics analysis identified TPI1 as a novel biomarker for predicting recurrence of intrahepatic cholangiocarcinoma.1 passage
• Proton pump inhibitor after endoscopic resection for esophageal squamous cell cancer: multicenter prospective randomized controlled trial.1 passage
• Proton pump inhibitor monotherapy is effective to attenuate dyspepsia symptoms associated with gastroesophageal reflux disease: a multicenter prospective observational study.1 passage
• Proton pump inhibitors as risk factor for metabolic syndrome and hepatic steatosis in coeliac disease patients on gluten-free diet.1 passage
• Proton-pump inhibitors are associated with a high false-positivity rate in faecal immunochemical testing.1 passage
• Quantitative diagnosis of chronic pancreatitis using EUS elastography.1 passage
• REFLECT-a phase 3 trial comparing efficacy and safety of lenvatinib to sorafenib for the treatment of unresectable hepatocellular carcinoma: an analysis of Japanese subset.1 passage
• Ramucirumab after prior sorafenib in patients with advanced hepatocellular carcinoma and elevated alpha-fetoprotein: Japanese subgroup analysis of the REACH-2 trial.1 passage
• Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma: Japanese subgroup analysis of the REACH trial.1 passage
• Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies.1 passage
• Real-time assessment of video images for esophageal squamous cell carcinoma invasion depth using artificial intelligence.1 passage
• Real-world effectiveness and safety of tolvaptan in liver cirrhosis patients with hepatic edema: results from a post-marketing surveillance study (START study).1 passage
• Real-world efficacy and safety of ledipasvir and sofosbuvir in patients with hepatitis C virus genotype 1 infection: a nationwide multicenter study by the Japanese Red Cross Liver Study Group.1 passage
• Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures.1 passage
• Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in Japan.1 passage
• Real-world virological efficacy and safety of elbasvir and grazoprevir in patients with chronic hepatitis C virus genotype 1 infection in Japan.1 passage
• Recent advancement in EUS-guided fine needle sampling.1 passage
• Recent advances in chemotherapy for pancreatic cancer: evidence from Japan and recommendations in guidelines.1 passage
• Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center.1 passage
• Recognition of and recent issues in hereditary diffuse gastric cancer.1 passage
• Recurrence hazard of rectal cancer compared with colon cancer by adjuvant chemotherapy status: a nationwide study in Japan.1 passage
• Recurrence patterns after surgical resection of intraductal papillary mucinous neoplasm (IPMN) of the pancreas; a multicenter, retrospective study of 1074 IPMN patients by the Japan Pancreas Society.1 passage
• Recurrent Clostridium difficile infection and the microbiome.1 passage
• Reducing adenoma miss rate of colonoscopy assisted by artificial intelligence: a multicenter randomized controlled trial.1 passage
• Reflux esophagitis and its role in the pathogenesis of Barrett's metaplasia.1 passage
• Regulation of virulence: the rise and fall of gastrointestinal pathogens.1 passage
• Relapse rate and predictors of relapse in a large single center cohort of type 1 autoimmune pancreatitis: long-term follow-up results after steroid therapy with short-duration maintenance treatment.1 passage
• Relationship between Barrett's esophagus and colonic diseases: a role for colonoscopy in Barrett's surveillance.1 passage
• Relationship between esophageal motility abnormalities and skin or lung involvements in patients with systemic sclerosis.1 passage
• Reply to "Letter to Editor submitted by Rui Huang et al. entitled potential clinical application of strain elastography in chronic liver diseases".1 passage
• Reply to the letter by Huo et al. regarding our manuscript "The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan".1 passage
• Resection depth and layer of cold snare polypectomy versus endoscopic mucosal resection.1 passage
• Residual HBV DNA and pgRNA viraemia is associated with hepatocellular carcinoma in chronic hepatitis B patients on antiviral therapy.1 passage
• Response criteria of tolvaptan for the treatment of hepatic edema.1 passage
• Response to the Letter by Lucijanic et al., regarding our manuscript "Management and outcome of gastro-intestinal bleeding in patients taking oral anticoagulants or antiplatelet drugs".1 passage
• Response to the Letter by Poddighe et al. regarding our manuscript "Basophils activated via TLR signaling may contribute to pathophysiology of type 1 autoimmune pancreatitis".1 passage
• Response to the letter by Dr. Costa-Moreira, Dr. Peixoto, Dr. Ramalho, and Dr. Macedo regarding our manuscript: "Relationship between esophageal motility abnormalities and skin or lung involvements in patients with systemic sclerosis".1 passage
• Response to the letter by Dr. Naoya Yamada, and Dr. Koichi Mizuta regarding our manuscript: "Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis".1 passage
• Response to the letter by Dr. Tomoyuki Kawada regarding our manuscript: Independent association between prediabetes and future pancreatic fat accumulation: a 5-year Japanese cohort study.1 passage
• Response to the letter by Lai et al. regarding our manuscript "Statin use and pancreatic cancer risk in two prospective cohort studies".1 passage
• Response to the letter by Matsushita et al. regarding our manuscript "Resection Depth and Layer of Cold Snare Polypectomy versus Endoscopic Mucosal Resection".1 passage
• Response to the letter by Sumida et al. regarding our manuscript "Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease".1 passage
• Retinoic acid receptor γ activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium.1 passage
• Retreatment with sofosbuvir, ledipasvir, and add-on ribavirin for patients who failed daclatasvir and asunaprevir combination therapy.1 passage
• Risk assessment of metachronous squamous cell carcinoma after endoscopic resection for esophageal carcinoma based on the genetic polymorphisms of alcoholdehydrogense-1B aldehyde dehydrogenase-2: temperance reduces the risk.1 passage
• Risk factors of nonadherence to colonoscopy surveillance after polypectomy and its impact on clinical outcomes: a KASID multicenter study.1 passage
• Risk of bleeding after endoscopic submucosal dissection for colorectal tumors in patients with continued use of low-dose aspirin.1 passage
• Risk of cardiovascular disease in patients with fatty liver disease as defined from the metabolic dysfunction associated fatty liver disease or nonalcoholic fatty liver disease point of view: a retrospective nationwide claims database study in Japan.1 passage
• Risk of gastric cancer in the second decade of follow-up after Helicobacter pylori eradication.1 passage
• Risk of metastasis in adenocarcinoma of the esophagus: a multicenter retrospective study in a Japanese population.1 passage
• Risk of metastatic recurrence after endoscopic resection for esophageal squamous cell carcinoma invading into the muscularis mucosa or submucosa: a multicenter retrospective study.1 passage
• Risk stratification and predictive risk-scoring model for lymph node metastasis in early gastric cancer.1 passage
• Role of contrast-enhanced ultrasonography with Sonazoid for hepatocellular carcinoma: evidence from a 10-year experience.1 passage
• Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease.1 passage
• Role of gastrointestinal hormones in feeding behavior and obesity treatment.1 passage
• Role of milk fat globule-epidermal growth factor 8 in colonic inflammation and carcinogenesis.1 passage
• Role of urgent contrast-enhanced multidetector computed tomography for acute lower gastrointestinal bleeding in patients undergoing early colonoscopy.1 passage
• SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer.1 passage
• STING and liver disease.1 passage
• Safety and effectiveness of sorafenib in Japanese patients with hepatocellular carcinoma in daily medical practice: interim analysis of a prospective postmarketing all-patient surveillance study.1 passage
• Safety and efficacy of dual direct-acting antiviral therapy (daclatasvir and asunaprevir) for chronic hepatitis C virus genotype 1 infection in patients on hemodialysis.1 passage
• Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.1 passage
• Safety and efficacy of elbasvir and grazoprevir in Japanese hemodialysis patients with genotype 1b hepatitis C virus infection.1 passage
• Safety and efficacy of glecaprevir and pibrentasvir in Japanese hemodialysis patients with genotype 2 hepatitis C virus infection.1 passage
• Safety and efficacy of lenvatinib by starting dose based on body weight in patients with unresectable hepatocellular carcinoma in REFLECT.1 passage
• Safety and efficacy of sorafenib in Japanese patients with hepatocellular carcinoma in clinical practice: a subgroup analysis of GIDEON.1 passage
• Safety of first-line triple therapy with a potassium-competitive acid blocker for Helicobacter pylori eradication in children.1 passage
• Sarcopenia in cirrhosis: from pathogenesis to interventions.1 passage
• Secondary prevention for hepatocellular carcinoma in patients with chronic hepatitis B: are all the nucleos(t)ide analogues the same?1 passage
• Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP1 passage
• Sensitivity of 2-[1 passage
• Sequential H. pylori eradication and radiation therapy with reduced dose compared to standard dose for gastric MALT lymphoma stages IE & II1E: a prospective randomized trial.1 passage
• Sequential therapy consisting of glucocorticoid infusions followed by granulocyte-monocyte absorptive apheresis in patients with severe alcoholic hepatitis.1 passage
• Serotonin disrupts esophageal mucosal integrity: an investigation using a stratified squamous epithelial model.1 passage
• Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.1 passage
• Serum Mac-2 binding protein glycosylation isomer predicts grade F4 liver fibrosis in patients with biliary atresia.1 passage
• Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts hepatocellular carcinoma incidence and recurrence in nucleos(t)ide analogue therapy for chronic hepatitis B.1 passage
• Serum aldo-keto reductase family 1 member B10 predicts advanced liver fibrosis and fatal complications of nonalcoholic steatohepatitis.1 passage
• Serum hepatitis B core-related antigen predicts hepatocellular carcinoma in hepatitis B e antigen-negative patients.1 passage
• Serum metabolomics analysis for early detection of colorectal cancer.1 passage
• Serum pepsinogen levels indicate the requirement of upper gastrointestinal endoscopy among Group A subjects of ABC classification: a multicenter study.1 passage
• Seventeen-year effects of eradicating Helicobacter pylori on the prevention of gastric cancer in patients with peptic ulcer; a prospective cohort study.1 passage
• Short sleep duration reduces the risk of nonalcoholic fatty liver disease onset in men: a community-based longitudinal cohort study.1 passage
• Short- and long-term outcomes of endoscopic submucosal dissection for early gastric cancer in the remnant stomach after gastrectomy.1 passage
• Short-term safety and efficacy of peroral endoscopic myotomy for the treatment of achalasia in children.1 passage
• Significance of endoscopic deep small bowel evaluation using balloon-assisted enteroscopy for Crohn's disease in clinical remission.1 passage
• Significance of exercise in nonalcoholic fatty liver disease in men: a community-based large cross-sectional study.1 passage
• Significance of liver dysfunction associated with decreased hepatic CT attenuation values in Japanese patients with severe COVID-19.1 passage
• Significance of variants associated with resistance to NS5A inhibitors in Japanese patients with genotype 1b hepatitis C virus infection as evaluated using cycling-probe real-time PCR combined with direct sequencing.1 passage
• Similarities and differences among eosinophilic esophagitis, proton-pump inhibitor-responsive esophageal eosinophilia, and reflux esophagitis: comparisons of clinical, endoscopic, and histopathological findings in Japanese patients.1 passage
• Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.1 passage
• Skeletal muscle depletion is an independent prognostic factor for hepatocellular carcinoma.1 passage
• Skeletal muscle mass to visceral fat area ratio is an important determinant affecting hepatic conditions of non-alcoholic fatty liver disease.1 passage
• Slow-metabolizing ADH1B and inactive heterozygous ALDH2 increase vulnerability to fatty liver in Japanese men with alcohol dependence.1 passage
• Small bowel injury in low-dose aspirin users.1 passage
• Sodium absorption stimulator prostasin (PRSS8) has an anti-inflammatory effect via downregulation of TLR4 signaling in inflammatory bowel disease.1 passage
• Sofosbuvir plus velpatasvir treatment for hepatitis C virus in patients with decompensated cirrhosis: a Japanese real-world multicenter study.1 passage
• Solving the questions regarding 5-aminosalitylate formulation in the treatment of ulcerative colitis.1 passage
• Splenic non-infarction volume determines a clinically significant hepatic venous pressure gradient response to partial splenic embolization in patients with cirrhosis and hypersplenism.1 passage
• Statin use and pancreatic cancer risk in two prospective cohort studies.1 passage
• Status of and candidates for cell therapy in liver cirrhosis: overcoming the "point of no return" in advanced liver cirrhosis.1 passage
• Stem cell dynamics and pretumor progression in the intestinal tract.1 passage
• Stem cell therapy for inflammatory bowel disease.1 passage
• Strain elastography for assessment of liver fibrosis and prognosis in patients with chronic liver diseases.1 passage
• Streptozocin chemotherapy for advanced/metastatic well-differentiated neuroendocrine tumors: an analysis of a multi-center survey in Japan.1 passage
• Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis.1 passage
• Supragastric belching in Japan: lower prevalence and relevance for management of gastroesophageal reflux disease compared to United Kingdom.1 passage
• Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial.1 passage
• Symptom-based diagnostic approach for eosinophilic esophagitis.1 passage
• Synergistic anti-tumor activity of miriplatin and radiation through PUMA-mediated apoptosis in hepatocellular carcinoma.1 passage
• Systematic review and meta-analysis of histopathological predictive factors for lymph node metastasis in T1 colorectal cancer.1 passage
• Systematic review with meta-analysis: loss of response and requirement of anti-TNFα dose intensification in Crohn's disease.1 passage
• Systematic review with meta-analysis: real-world effectiveness and safety of vedolizumab in patients with inflammatory bowel disease.1 passage
• Systematic review with network meta-analysis: indirect comparison of the efficacy of vonoprazan and proton-pump inhibitors for maintenance treatment of gastroesophageal reflux disease.1 passage
• Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes.1 passage
• Systemic treatment options for advanced biliary tract carcinoma.1 passage
• TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota.1 passage
• TLL1 variant associated with development of hepatocellular carcinoma after eradication of hepatitis C virus by interferon-free therapy.1 passage
• Targeting the immune milieu in gastrointestinal cancers.1 passage
• Telomere length of gallbladder epithelium is shortened in patients with congenital biliary dilatation: measurement by quantitative fluorescence in situ hybridization.1 passage
• Tenofovir-disoproxil-fumarate modulates lipid metabolism via hepatic CD36/PPAR-alpha activation in hepatitis B virus infection.1 passage
• The 2016 diagnostic criteria for primary sclerosing cholangitis.1 passage
• The association between retinal microvascular changes, metabolic risk factors, and liver histology in pediatric patients with non-alcoholic fatty liver disease (NAFLD).1 passage
• The characteristics of gastrointestinal symptoms in patients with severe COVID-19: a systematic review and meta-analysis.1 passage
• The clinical efficacy of azathioprine as maintenance treatment for autoimmune pancreatitis: a systematic review and meta-analysis.1 passage
• The clinical features of patients with a Y93H variant of hepatitis C virus detected by a PCR invader assay.1 passage
• The combination of elbasvir and grazoprevir for the treatment of chronic HCV infection in Japanese patients: a randomized phase II/III study.1 passage
• The course of elderly patients with persistent hepatitis C virus infection without hepatocellular carcinoma.1 passage
• The effects of diuretic use and the presence of ascites on muscle cramps in patients with cirrhosis: a nationwide study.1 passage
• The first management using intubation of a nasogastric tube with Gastrografin enterography or long tube for non-strangulated acute small bowel obstruction: a multicenter, randomized controlled trial.1 passage
• The genetic classification of pancreatic neoplasia.1 passage
• The gut mycobiome: a novel player in chronic liver diseases.1 passage
• The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.1 passage
• The identification of celiac disease in asymptomatic children: the Generation R Study.1 passage
• The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus.1 passage
• The impact of an inosine triphosphate pyrophosphatase genotype on bilirubin increase in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin.1 passage
• The influence of familial pancreatic cancer on postoperative outcome in pancreatic cancer: relevance to adjuvant chemotherapy.1 passage
• The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease.1 passage
• The long-term outcomes of patients with immunoglobulin G4-related sclerosing cholangitis: the Mayo Clinic experience.1 passage
• The mesenchymal stem cell secretome as an acellular regenerative therapy for liver disease.1 passage
• The microbiome can predict mucosal healing in small intestine in patients with Crohn's disease.1 passage
• The microbiota in inflammatory bowel disease.1 passage
• The morbidity and associated risk factors of cancer in chronic liver disease patients with diabetes mellitus: a multicenter field survey.1 passage
• The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study.1 passage
• The profiling of plasma free amino acids and the relationship between serum albumin and plasma-branched chain amino acids in chronic liver disease: a single-center retrospective study.1 passage
• The prognosis of hepatitis B inactive carriers in Japan: a multicenter prospective study.1 passage
• The prospective randomized study on telaprevir at 1500 or 2250 mg with pegylated interferon plus ribavirin in Japanese patients with HCV genotype 1.1 passage
• The recovery of the PT-INR to less than 1.3 predicts survival in patients with severe acute liver injury.1 passage
• The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients.1 passage
• The relationship between the PD-L1 expression of surgically resected and fine-needle aspiration specimens for patients with pancreatic cancer.1 passage
• The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease.1 passage
• The role of maintenance therapy in eosinophilic esophagitis: who, why, and how?1 passage
• The role of microRNA in esophageal squamous cell carcinoma.1 passage
• The role of small intestinal bacterial overgrowth in cystic fibrosis: a randomized case-controlled clinical trial with rifaximin.1 passage
• The safety and efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 1b infection.1 passage
• The shining DIAMOND for evidence-based treatment strategies for Crohn's disease.1 passage
• The state of the art on treatment of Crohn's disease.1 passage
• The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan.1 passage
• The tumor-stromal ratio as a strong prognosticator for advanced gastric cancer patients: proposal of a new TSNM staging system.1 passage
• The value of preoperative screening colonoscopies in patients with biliary tract cancer.1 passage
• The value of systematic lymph node dissection for intrahepatic cholangiocarcinoma from the viewpoint of liver lymphatics.1 passage
• The von Willebrand Factor antigen to platelet ratio (VITRO) score predicts hepatic decompensation and mortality in cirrhosis.1 passage
• Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology.1 passage
• Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease.1 passage
• Time series analysis of gastric acid secretion over a 20-year period in normal Japanese men.1 passage
• Time trends in the incidence of esophageal adenocarcinoma, gastric adenocarcinoma, and superficial esophagogastric junction adenocarcinoma.1 passage
• To die or not to die: death signaling in nonalcoholic fatty liver disease.1 passage
• Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression.1 passage
• Trajectories of glycaemia following acute pancreatitis: a prospective longitudinal cohort study with 24 months follow-up.1 passage
• Transarterial chemoembolization with miriplatin vs. epirubicin for unresectable hepatocellular carcinoma: a phase III randomized trial.1 passage
• Transition in the etiology of liver cirrhosis in Japan: a nationwide survey.1 passage
• Treatment of hepatitis C in special populations.1 passage
• Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution.1 passage
• Treatment with sofosbuvir and ledipasvir without ribavirin for 12 weeks is highly effective for recurrent hepatitis C virus genotype 1b infection after living donor liver transplantation: a Japanese multicenter experience.1 passage
• Trends in incidence of small bowel cancer according to histology: a population-based study.1 passage
• Tumor-specific genetic aberrations in cell-free DNA of gastroesophageal cancer patients.1 passage
• Tumor/normal esophagus ratio in (18)F-fluorodeoxyglucose positron emission tomography/computed tomography for response and prognosis stratification after neoadjuvant chemotherapy for esophageal squamous cell carcinoma.1 passage
• Two randomized controlled studies comparing the nutritional benefits of branched-chain amino acid (BCAA) granules and a BCAA-enriched nutrient mixture for patients with esophageal varices after endoscopic treatment.1 passage
• Ulcerative colitis-related severe enteritis: an infrequent but serious complication after colectomy.1 passage
• Unresolved issues of immune tolerance in chronic hepatitis B.1 passage
• Upregulated absorption of dietary palmitic acids with changes in intestinal transporters in non-alcoholic steatohepatitis (NASH).1 passage
• Urinary excretion of the water channel aquaporin 2 correlated with the pharmacological effect of tolvaptan in cirrhotic patients with ascites.1 passage
• Usefulness of nutritional therapy recommended in the Japanese Society of Gastroenterology/Japan Society of Hepatology evidence-based clinical practice guidelines for liver cirrhosis 2020.1 passage
• Usefulness of transabdominal ultrasonography for assessing ulcerative colitis: a prospective, multicenter study.1 passage
• Utility of a new automated diagnostic program in high-resolution esophageal manometry.1 passage
• Utility of surrogate markers for the prediction of relapses in inflammatory bowel diseases.1 passage
• Validation of serological models for staging and prognostication of HCC in patients from a Japanese nationwide survey.1 passage
• Vaniprevir plus peginterferon alfa-2a and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase II study.1 passage
• Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-naive Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase III study.1 passage
• Verrucous esophageal carcinoma is a unique indolent subtype of squamous cell carcinoma: a systematic review and individual patient regression analysis.1 passage
• Virological and Clinical Characteristics of Hepatitis B Virus Genotype A.1 passage
• Vonoprazan-based triple therapy is effective for Helicobacter pylori eradication irrespective of clarithromycin susceptibility.1 passage
• What is causing the rising incidence of esophageal adenocarcinoma in the West and will it also happen in the East?1 passage
• Wilson disease: revision of diagnostic criteria in a clinical series with great genetic homogeneity.1 passage
• Wisteria floribunda agglutinin positive Mac-2-binding protein level increases in patients with acute liver injury.1 passage
• Wisteria floribunda agglutinin-sialylated mucin core polypeptide 1 is a sensitive biomarker for biliary tract carcinoma and intrahepatic cholangiocarcinoma: a multicenter study.1 passage
• Withdrawal of thiopurines in Crohn's disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2).1 passage
• World trends for H. pylori eradication therapy and gastric cancer prevention strategy by H. pylori test-and-treat.1 passage
• YAP and the Hippo pathway in cholangiocarcinoma.1 passage
• miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway.1 passage
• miR-33a levels in hepatic and serum after chronic HBV-induced fibrosis.1 passage
• pH Impedance vs. traditional pH monitoring in clinical practice: an outcome study.1 passage