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abstractpubmed· Abstract 2021· item PMID:34728984

A case series of amoebic liver abscess in patients with COVID-19 infection. Background: Globally amoebiasis is the second leading cause of death due to parasitic diseases. Amoebic liver abscess (ALA) as an opportunistic infection in recently recovered COVID 19 disease patients has not been reported earlier. Methods: We present here case series of 13 patients of ALA admitted during the month of May 2021 in BLK hospital, New Delhi and had recently recovered from COVID 19 disease. Results: Out of 13, eight patients had moderate and one had severe COVID 19 disease. All these patients had received steroids for management of COVID 19 disease. Rest of 4(30%) patients had mild disease. The mean age of our patients was 50 years (37-81 years). Out of 13 patients, nine (70%) were male, 5 were diabetic, 2 were hypertensive and none were alcoholic. The most common presentation was fever (11/13) followed by pain upper abdomen (10/13). The mean time of symptom (fever or pain abdomen) onset from COVID 19 positivity date was 19 days (range 15-23 days). Complication in form of localised intra-peritoneal rupture was common in these patients and was seen in more than 50% (7/13) of patients. All the patients were managed with IV Metronidazole and abscess aspiration. All the patients were discharged and mean hospital stay was 6.6 days. Conclusion: We report here increase in incidence of ALA in recently recovered COVID 19 patients and propose that it is most likely due alteration in immune state of these patients. It is important for physicians to investigate for liver abscess in patients who presents again with fever and/or pain abdomen within 2 weeks of COVID 19 recovery.