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abstractpubmed· Abstract 2017· item PMID:28437518

A Middle-aged Man With Progressive Ophthalmoparesis, Ataxia, and Spastic Paraparesis. A 50-year old man presented for evaluation of progressive gait ataxia with a superimposed spastic paraparesis. During his clinic visit, he was also observed to have slow and limited eye movements. In this article, we discuss the clinical approach to this triad of symptoms and guide the reader to discover the patient's ultimate genetic diagnosis.