Browse the corpus

Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• A novel echocardiographic imaging technique, intracatheter echocardiography, to guide veno-venous extracorporeal membrane oxygenation cannulae placement in a validated ovine model Platts24 passages
• A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair Duffy29 passages
• A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models http://orcid.org/0000-0001-9803-9701Dhanani40 passages
• Accelerated clearance of human red blood cells in a rat transfusion model9 passages
• Acute organ injury is associated with alterations in the cell-free plasma transcriptome Boyd18 passages
• Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome Henderson33 passages
• Adrenomedullin binding improves catecholamine responsiveness and kidney function in resuscitated murine septic shock Wagner Katja katja.wagner@uni-ulm.de Wachter Ulrich ulrich.wachter@uni-ulm.de Vogt30 passages
• Advanced modes of mechanical ventilation and optimal targeting schemes http://orcid.org/0000-0002-7332-1062van der Staay Matthias +41 81 750 06 33vanderstaay@imt.ch 1Chatburn39 passages
• Allostasis and sedation practices in intensive care evaluation: an observational pilot study http://orcid.org/0000-0001-9039-1014Moore24 passages
• Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen Jang31 passages
• Alveolar dynamics during mechanical ventilation in the healthy and injured lung Grune Jana jana.grune@charite.de 12Tabuchi Arata art_t@mac.com 1Kuebler40 passages
• Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury Andrews20 passages
• An authentic animal model of the very preterm infant on nasal continuous positive airway pressure Dargaville23 passages
• An extracorporeal carbon dioxide removal (ECCO2R) device operating at hemodialysis blood flow rates23 passages
• An improved mounting device for attaching intracranial probes in large animal models Dunster9 passages
• Analysis of the influence of antithrombin on microvascular thrombosis: anti-inflammation is crucial for anticoagulation Sorg Heiko +49 381 494 2500heiko.sorg@krupp-krankenhaus.de Hoffmann22 passages
• Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support Suffredini25 passages
• Aortic volume determines global end-diastolic volume measured by transpulmonary thermodilution Akohov Aleksej 1Barner Christoph 1Grimmer Steffen 13Francis27 passages
• Assessment of ventilation inhomogeneity during mechanical ventilation using a rapid-response oxygen sensor-based oxygen washout method Bikker28 passages
• Automated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output Berlin23 passages
• Baseline thrombospondin-1 concentrations are not associated with mortality in septic patients: a single-center cohort study on the intensive care unit van der Wekken17 passages
• Bench Validation of a Compact Low-Flow CO2 Removal Device May25 passages
• Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis Mai28 passages
• Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model Reddi32 passages
• Carbon dioxide dialysis in a swine model utilizing systemic and regional anticoagulation22 passages
• Catheter securement systems: comparison of two investigational devices to a sutureless securement device, a securement dressing, and sutures in a pig model Rutledge31 passages
• Centre of Emergency Medicine, Aarhus University, Nørrebrogade 44, 800030 passages
• Centre, Toronto, Canada 15 University of Birmingham, Institute for Inflammation and Ageing, Birmingham, UK 16 University of Sheffield, Mathematics and Statistics Help Centre, Sheffield, UK 17 Heart of1396 passages
• Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis http://orcid.org/0000-0002-5332-5883Busch37 passages
• Comparison between effects of pressure support and pressure-controlled ventilation on lung and diaphragmatic damage in experimental emphysema Padilha Gisele de A. giseleapadilha@gmail.com 1Horta40 passages
• Comparison of the source and prognostic utility of cfDNA in trauma and sepsis Jackson Chornenki19 passages
• Contrast-enhanced ultrasound evaluation of renal microcirculation in sheep Schneider25 passages
• Council (GB)G1002017Hardman22 passages
• Council2014-3140Ley David http://dx.doi.org/10.13039/501100003793Hjärt-Lungfonden2014063120160721Gram Magnus Ley32 passages
• CouncilERC-2007-StG 20777Laffey26 passages
• Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation Owen27 passages
• Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis Peng Zhi-Yong Zhou Feihu Kellum15 passages
• Determining rhythmicity and determinism of temperature curves in septic and non-septic critically ill patients through chronobiological and recurrence quantification analysis: a pilot study Papaioannou42 passages
• Development of a model for anemia of inflammation that is relevant to critical care http://orcid.org/0000-0002-2019-9147Boshuizen Margit m.boshuizen@amc.nl 12van Bruggen Robin 2Zaat18 passages
• Dynamic single-slice CT estimates whole-lung dual-energy CT variables in pigs with and without experimental lung injury Cronin35 passages
• Effect of PEEP on breath sound power spectra in experimental lung injury Räsänen Jukka Jukka.Rasanen@moffitt.org Nemergut25 passages
• Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock Vogt27 passages
• Effects of norepinephrine on tissue perfusion in a sheep model of intra-abdominal hypertension Ferrara Gonzalo gonzaloferrara@gmail.com Kanoore Edul27 passages
• Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review Obonyo24 passages
• Extracorporeal CO2 removal by hemodialysis: in vitro model and feasibility May21 passages
• Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models http://orcid.org/0000-0002-4853-9377Millar29 passages
• Gaseous mediators: an updated review on the effects of helium beyond blowing up balloons Weber27 passages
• Group, Adult Critical Care Unit, The Royal London Hospital, Barts28 passages
• Heart rate variability in critical care medicine: a systematic review Karmali30 passages
• Hemoadsorption corrects hyperresistinemia and restores anti-bacterial neutrophil function Bonavia Anthony abonavia@pennstatehealth.psu.edu 1Miller Lauren lmiller18@pennstatehealth.psu.edu 1Kellum30 passages
• Heparin-binding protein is important for vascular leak in sepsis Bentzer Peter 124Fisher Jane 34Kong HyeJin Julia 4Mörgelin Mattias 3Boyd31 passages
• Histopathological changes of organ dysfunction in sepsis Garofalo34 passages
• Hyperoxia provokes a time- and dose-dependent inflammatory response in mechanically ventilated mice, irrespective of tidal volumes Helmerhorst28 passages
• IL-1β processing in mechanical ventilation-induced inflammation is dependent on neutrophil factors rather than caspase-1 Timmermans Kim Kim.Timmermans@radboudumc.nl van der Wal24 passages
• Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock http://orcid.org/0000-0002-5519-9171Merz Tamara +49 731 500 60182tamara.merz@uni-ulm.de 1Vogt28 passages
• Improving animal welfare using continuous nalbuphine infusion in a long-term rat model of sepsis Jeger Victor victor.jeger@usz.ch 12Arrigo Mattia mattia.arrigo@usz.ch 3Hildenbrand32 passages
• In vitro comparison between inspiration synchronized and continuous vibrating mesh nebulizer during trans-nasal aerosol delivery http://orcid.org/0000-0003-0121-1291Li Jie Jie_Li@rush.edu 1Wu Wei 2Fink23 passages
• Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response http://orcid.org/0000-0001-7519-9841Schouten35 passages
• Institute, Barts and the London School of Medicine and Dentistry, London, UK Adult Critical Care Unit, Royal London Hospital, Barts3 passages
• Institute, London, United Kingdom Barts7 passages
• Institute, London, United Kingdom Barts & the London School of Medicine, QMUL, Blizard Institute, London, United Kingdom Barts2 passages
• Institute, Neurosurgery, Moscow, Russian Federation Sklifosovsky Research Institute,2 passages
• Institute, Queen Mary University of London, London, United Kingdom University College London, London, United Kingdom Barts2 passages
• Institute, São Paulo,3 passages
• Intensive Care Med Exp7639 passages
• Left ventricular function during porcine-resuscitated septic shock with pre-existing atherosclerosis Nußbaum29 passages
• Low flow rate alters haemostatic parameters in an ex-vivo extracorporeal membrane oxygenation circuit Ki27 passages
• Lung anatomy, energy load, and ventilator-induced lung injury Protti Alessandro alessandro.protti@policlinico.mi.it Andreis40 passages
• Lung stress, strain, and energy load: engineering concepts to understand the mechanism of ventilator-induced lung injury (VILI) Nieman14 passages
• Manipulation of the microbiome in critical illness—probiotics as a preventive measure against ventilator-associated pneumonia van Ruissen25 passages
• Mechanical ventilation with heliox in an animal model of acute respiratory distress syndrome Beurskens20 passages
• Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells Michels Monique moniquemichels@hotmail.com Steckert25 passages
• Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury Hayes Mairead hayesmairead@hotmail.com Curley26 passages
• Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns Masterson45 passages
• Modulation of monocytes in septic patients: preserved phagocytic activity, increased ROS and NO generation, and decreased production of inflammatory cytokines Santos Sidnéia S. Carmo30 passages
• Myeloperoxidase can differentiate between sepsis and non-infectious SIRS and predicts mortality in intensive care patients with SIRS http://orcid.org/0000-0002-3904-5893Schrijver18 passages
• N/AStrong James E. Government of CanadaN/AStrong27 passages
• Network and the PROVE Network Investigators1363 passages
• Network on Maternal and Child Health and26 passages
• Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis) de Jong33 passages
• Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury http://orcid.org/0000-0002-4837-4074Watts35 passages
• Outcomes Melia U. 86Fontanet J. 86van den1377 passages
• PEEP titration: the effect of prone position and abdominal pressure in an ARDS model http://orcid.org/0000-0002-8843-3673Keenan24 passages
• Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI) Nieman36 passages
• Positional effects on the distributions of ventilation and end-expiratory gas volume in the asymmetric chest—a quantitative lung computed tomographic analysis Cortes-Puentes28 passages
• Power to mechanical power to minimize ventilator-induced lung injury? Silva Pedro Leme pedro.leme@gmail.com 1Ball Lorenzo lorenzo.loryball@gmail.com 23http://orcid.org/0000-0003-1412-7136Rocco17 passages
• Predictive validity of a novel non-invasive estimation of effective shunt fraction in critically ill patients Chang18 passages
• Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS http://orcid.org/0000-0001-7098-6969de Beer20 passages
• Quantification of perflutren microsphere contrast destruction during transit through an ex vivo extracorporeal membrane oxygenation circuit Platts27 passages
• Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines Remy30 passages
• Resistin directly inhibits bacterial killing in neutrophils Miller Lauren lmiller18@pennstatehealth.psu.edu 1Singbartl Kai ks.ms@posteo.de 2Chroneos27 passages
• Respiratory and metabolic acidosis correction with the ADVanced Organ Support system Perez Ruiz de Garibay Aritz aritz.perez@advitos.com 1Kellum43 passages
• Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis Patrick34 passages
• Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism Walshe24 passages
• Sepsis-induced acute kidney injury by standardized colon ascendens stent peritonitis in rats - a simple, reproducible animal model Schick28 passages
• Serum proteomics as a strategy to identify novel biomarkers of neurologic recovery after cardiac arrest: a feasibility study19 passages
• Shape descriptors of the “never resting” microglia in three different acute brain injury models in mice Zanier40 passages
• Systemic and microcirculatory effects of blood transfusion in experimental hemorrhagic shock Ferrara Gonzalo gonzaloferrara@gmail.com 1Edul30 passages
• Systemic and renal hemodynamic effects of intra-arterial radiocontrast Calzavacca Paolo p.calzavacca@gmail.com Ishikawa Ken kenishi2007@gmail.com Bailey Michael michael.bailey@monash.edu May21 passages
• Team, London, United Kingdom Queen Mary University of London, William Harvey Institute, LONDON, United Kingdom Barts3 passages
• The 30-year evolution of airway pressure release ventilation (APRV) Jain35 passages
• The effects of airway pressure release ventilation on respiratory mechanics in extrapulmonary lung injury Kollisch-Singule Michaela KolliscM@upstate.edu Emr Bryanna EmrB@upstate.edu Jain30 passages
• The effects of hyperoxia on microvascular endothelial cell proliferation and production of vaso-active substances http://orcid.org/0000-0003-1274-3453Attaye Ilias i.attaye@vumc.nl 12Smulders33 passages
• The endotoxin-induced pulmonary inflammatory response is enhanced during the acute phase of influenza infection19 passages
• The metabolic phenotype of rodent sepsis: cause for concern? Zolfaghari28 passages
• The novel nitric oxide donor PDNO attenuates ovine ischemia-reperfusion induced renal failure Nilsson24 passages
• The peripheral blood transcriptome in septic cardiomyopathy: an observational, pilot study http://orcid.org/0000-0003-1520-1713Cirulis18 passages
• The physiological determinants of near-infrared spectroscopy-derived regional cerebral oxygenation in critically ill adults Wood33 passages
• The receptor for advanced glycation end products in ventilator-induced lung injury Kuipers25 passages
• The role of calpains in ventilator-induced diaphragm atrophy Zhu Xiaoping z_xping@hotmail.com 1van Hees27 passages
• The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model Jain38 passages
• Tight junction structure, function, and assessment in the critically ill: a systematic review Vermette David David.vermette@yale.edu 1Hu Pamela Pamela.hu@yale.edu 1Canarie39 passages
• Time-dependent effects of histone deacetylase inhibition in sepsis-associated acute kidney injury Wen Xiaoyan 1Li Shengnan 1Frank Alicia 1Chen Xiukai 1Emlet David 1Hukriede32 passages
• Tumor necrosis factor receptor 1 (TNFRI) for ventilator-associated pneumonia diagnosis by cytokine multiplex analysis Martin-Loeches Ignacio +353 (01) 410 3000drmartinloeches@gmail.com Bos23 passages
• Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine Cain41 passages
• Unilateral mechanical asymmetry: positional effects on lung volumes and transpulmonary pressure Cortes-Puentes21 passages
• Unit Sepsis, Lyon, France Hospices Civils de Lyon,3 passages
• Unit, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain 3 0000 0000 9314 1427grid.413448.eCIBER de Enfermedades Respiratorias, Instituto de Salud28 passages
• Use of a high platelet-to-RBC ratio of 2:1 is more effective in correcting trauma-induced coagulopathy than a ratio of 1:1 in a rat multiple trauma transfusion model Kleinveld24 passages
• VUmc Intensive Care (REVIVE),24 passages
• Validation of computed tomography for measuring lung weight Protti Alessandro alessandro.protti@policlinico.mi.it Iapichino15 passages
• Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis Drechsler Susanne susanne.drechsler@trauma.lbg.ac.at Weixelbaumer44 passages