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abstractpubmed· Abstract 2020· item PMID:32284483

Wernicke Encephalopathy and Lactic Acidosis in Thiamine Deficiency. Thiamine deficiency can cause encephalopathy (Wernicke) and lactic acidosis. Herein we report a 6-year-old girl on total parenteral nutrition (TPN) who developed lactic acidosis and neurological symptoms due to improper vitamin replacement, which responded to thiamine injection. The MRI brain findings were not typical for Wernicke encephalopathy.