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Progression of Thyrotropinemia in Overweight and Obese Children From Puducherry, India. OBJECTIVE: To assess the progression of thyrotropinemia to overt hypothyroidism in overweight and obese children. METHOD: 150 overweight and obese children aged 5-15 years were enrolled. Free T4 and thyroid stimulating hormone (TSH) were done at enrollment and for those with TSH >5 mIU/L, TSH levels were repeated after 1 year. RESULTS: The mean (SD) body mass index (BMI) and TSH were 23.8 (3.19) kg/m2 and 2.70 (2.44) mIU/L, respectively. 17 children had thyrotropinemia (TSH between 10-15mIU/L); 10 (84.6%) of these children attained normal TSH levels at one year follow-up, and none progressed to overt hypothyroidism (TSH >15 mlU/L). CONCLUSION: Levels of 5-15 mIU/L are common in asymptomatic overweight and obese children. Majority of these children revert back to normal TSH levels on follow-up.