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Profile of Retinopathy of Prematurity in Outborn and Inborn Babies at a Tertiary Eye Care Hospital. OBJECTIVE: To study the profile of retinopathy of prematurity (ROP) among outborn and inborn babies at a tertiary-care centre. METHODOLOGY: In a prospective observational study from 2015-2016, outborn and inborn babies eligible for ROP screening were evaluated for ROP profile and treatment results. RESULTS: 532 outborns and 38 inborns had ROP. Respi-ratory distress, sepsis and apnea were present in 81.3%, 51.5% and 36.2% of outborns with ROP and 68.4%, 39.4% and 36.8% of inborns with ROP. Type 1 ROP was noted in 49.2% eyes of outborns with ROP and 36.8% eyes of inborns with ROP. Type 1 ROP regressed with laser in 97.3% and 100% eyes of outborn and inborn with ROP, respectively. Stage 4, 5 and sequelae were noted in 5.2%, 22.8% and 4.6% eyes of outborns with ROP, respectively, but none in inborns. CONCLUSIONS: Quality neonatal care and timely screening ensured lesser ROP-related morbidity in inborns as compared to outborns.