Browse the corpus
Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.
1 passage
Favorable Renal Outcome of Japanese Children with Severe IgA Nephropathy With Nephrotic Syndrome. BACKGROUND: Nephrotic syndrome is a rare but severe feature of IgA nephropathy. CASE CHARACTERISTICS: Nine Japanese children with severe IgA nephropathy with nephrotic syndrome. INTERVENTION: All received low-dose intravenous methylprednisolone (IVMP) within five weeks after the disease onset. Eight out of nine patients achieved resolution of proteinuria without severe adverse events. MESSAGE: Early low-dose intravenous methylprednisolone may be safe and effective for children with severe IgA nephropathy with nephrotic syndrome.