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abstractpubmed· Abstract 2018· item PMID:30218513

Encephalitic presentation of Neonatal Chikungunya: A Case Series. OBJECTIVE: To describe clinical features and early neurological outcomes in neonatal Chikungunya. METHODS: Clinical, pathological and radiological details of neonates with acute encephalitic features and typical rash, later diagnosed as Chikungunya, are presented. Neurodevelopmental evaluation and imaging was done at discharge/three months. RESULTS: Abnormal neurological examination with fever was typical presentation in all 13 babies with/without seizures/peri-oral rashes; 12 had persistent neurological abnormalities at discharge. A follow-up at three months revealed continued neurodevelopmental deficits. Neuroimaging abnormalities were seen in eight out of ten cases. CONCLUSIONS: Perinatal Chikungunya should be considered in neonates presenting within first week with fever, encephalopathy and perioral rashes with/without seizures with history of maternal Chikungunya within last week before delivery.