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abstractpubmed· Abstract 2016· item PMID:27029685

Bacterial Pathogens Associated with Community-acquired Pneumonia in Children Aged Below Five Years. OBJECTIVE: To determine the spectrum of bacterial pathogens causing community-acquired pneumonia in children below 5 years of age. METHODS: Children aged below 5 years satisfying the WHO criteria for pneumonia, severe pneumonia or very severe pneumonia, and with the presence of lung infiltrates on chest X-ray were enrolled. Two respiratory samples, one for culture and the other for PCR analysis, and a blood sample for culture were collected from every child. RESULTS: Of the 180 samples processed, bacterial pathogens were detected in 64.4%. Streptococcus pneumoniae and Hemophilus influenzae were most frequently detected. The performance of PCR analysis and culture were identical for the typical bacterial pathogens; atypical pathogens were detected by PCR analysis only. CONCLUSION: S. pneumoniae and H. influenza were the most commonly detected organisms from respiratory secretions of children with community acquired pneumonia.