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Ankyloglossia in Infancy: An Indian Experience. OBJECTIVE: To study the prevalence, clinical presentation and management of infants with ankyloglossia. METHODS: A retrospective file review of infants less than 6 months of age with a diagnosis of ankyloglossia. Results: Of the 25786 babies born during the assessment period (2007-2015), 134 (0.52%) had ankyloglossia. Sixty-four (47.7%) infants who presented with breastfeeding difficulties were diagnosed significantly earlier than the asymptomatic group (P<0.05). Of the symptomatic group, 85.9% underwent frenotomy with satisfactory results. Seventy asymptomatic infants were managed conservatively with counselling. CONCLUSION: Frenotomy seems to be a safe and effective procedure in infants with symptomatic ankyloglossia.