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Depression, Anxiety, and Parenting Stress among Mothers of Children with West Syndrome. The present cross-sectional study was designed to determine the prevalence of depression, anxiety, and parenting stress in mothers of children aged 6 mo to 5 y with West syndrome compared to mothers of healthy children. The enrolled mothers were subjected to interview-based administration of the Hamilton Anxiety Scale (HAS), Beck Depression Inventory (BDI-II), and Parenting Stress Scale (PSS). Maternal anxiety [HAM score: 9 (5, 14) vs. 1 (0, 2.2); p < 0.01], depression [BDI score: 11 (7, 19) vs. 1 (0, 3); p < 0.01], and parental stress [PSS score: 40 (32, 45) vs. 22 (20, 24); p < 0.01] were significantly higher among mothers of children with West syndrome when compared to controls. Logistic regression revealed maternal education to be a significant predictor of depression among mothers of children with West syndrome. Anxiety, depression, and parental stress were higher among mothers of children with West syndrome and they should be additionally screened.