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abstractpubmed· Abstract 2019· item PMID:31441758
Use of Human Intestinal Enteroids to Detect Human Norovirus Infectivity. Tools to detect human norovirus infectivity have been lacking. Using human intestinal enteroid cultures inoculated with GII.Pe-GII.4 Sydney-infected fecal samples, we determined that a real-time reverse transcription PCR cycle threshold cutoff of 30 may indicate infectious norovirus. This finding could be used to help guide infection control.