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abstractpubmed· Abstract 2021· item PMID:34287131
Replication in Human Intestinal Enteroids of Infectious Norovirus from Vomit Samples. A typical clinical symptom of human norovirus infection is projectile vomiting. Although norovirus RNA and viral particles have been detected in vomitus, infectivity has not yet been reported. We detected replication-competent norovirus in 25% of vomit samples with a 13-fold to 714-fold increase in genomic equivalents, confirming infectious norovirus.