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Real-Time Projections of SARS-CoV-2 B.1.1.7 Variant in a University Setting, Texas, USA. We used the incidence of spike gene target failures identified during PCR testing to provide an early projection of the prevalence of severe acute respiratory syndrome coronavirus 2 variant B.1.1.7 in a university setting in Texas, USA, before sequencing results were available. Findings from a more recent evaluation validated those early projections.