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abstractpubmed· Abstract 2018· item PMID:30016251
Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab. Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore impaired T-cell responses in patients with cancer and infections. Data for 4 other cases were obtained from pharmacovigilance databases.