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Melioidosis Manifesting as Chronic Femoral Osteomyelitis in Patient from Ghana. A 33-year-old man from Ghana who had diabetes also had chronic osteomyelitis of the femoral shaft. Tissue samples from surgical debridement grew Burkholderia pseudomallei. He received meropenem, followed by oral trimethoprim/sulfamethoxazole and doxycycline, and fully recovered without complications. Our case report extends the range of countries in Africa as sources of culture-confirmed melioidosis.