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abstractpubmed· Abstract 2021· item PMID:34161223
Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland. We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.