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abstractpubmed· Abstract 2018· item PMID:30016255

Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010-2012. Skin biopsies from US leprosy patients were tested for mutations associated with drug resistance. Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients. No resistance was observed in patients from other origins. The high rate of dapsone resistance in patients from American Samoa warrants further investigation.