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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.
1 passage
Diagnosis of Lyme disease in the pediatric acute care setting. PURPOSE OF REVIEW: We review the current evidence concerning the diagnosis of Lyme disease in children for application in the acute care setting. RECENT FINDINGS: Recent studies suggest that Lyme disease incidence is substantially higher than previously described. Although efforts are ongoing to identify alternative testing strategies, two-tiered serologic testing remains the diagnostic standard in children with compatible clinical syndromes. Published clinical prediction rules can assist clinicians caring for children with potential Lyme disease. SUMMARY: Two-tiered serologic testing remains the mainstay of the diagnosis of Lyme disease. To minimize the risk of a false positive test, serologic testing should be limited to those children with symptoms compatible with Lyme disease with potential exposure to ticks from endemic regions.