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abstractpubmed· Abstract 2019· item PMID:30691711
Immunomodulators and Biologics: Beyond Stepped-Care Therapy. This review highlights recent data concerning efficacy and safety of biological agents that are currently approved by Food and Drug Administration (FDA), as well as several agents that will likely soon be FDA approved, for management of properly selected patients with severe persistent asthma that is poorly or not well controlled despite "stepped care" management according to best evidence.