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abstractpubmed· Abstract 2018· item PMID:30290953
Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication. Idiopathic pulmonary fibrosis is the most common idiopathic interstitial pneumonia. Prognosis is poor with a median survival <3 years. Pirfenidone is one of two US Food and Drug Administration-approved medications that slow disease progression. We describe the development of lymphadenopathy or a sarcoid-like reaction following initiation of pirfenidone, a complication not previously reported.