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abstractpubmed· Abstract 2016 Sep-Dec· item PMID:28203129

Plasmapheresis for Refractory Pruritus due to Drug-Induced Cholestasis. Pruritus can be a distressing symptom seen in various cholestatic disorders. It is treated with medications like bile acid sequestrants. Drug-induced cholestasis usually resolves with withdrawal of the causative medication. We describe a case of refractory pruritus due to drug-induced cholestasis, not improved with withdrawal of the drug, managed effectively with multiple sessions of plasmapheresis.