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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• 'Diagnostic downshift': clinical and system consequences of extrapolating secondary care testing tactics to primary care.1 passage
• A cross-sectional study to assess Evidence-Based Medicine teaching method: online or face-to-face?1 passage
• A unique framework for the Persian clinical guidelines: addressing an evidence-based CDSS development need.1 passage
• Adherence in leading medical journals to the CONSORT 2010 statement for reporting of binary outcomes in randomised controlled trials: cross-sectional analysis.1 passage
• Adherence to reporting guidelines and clinical trial registration policies in oncology journals: a cross-sectional review.1 passage
• Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: restoration of previously unpublished methodology.1 passage
• An evidence map of randomised controlled trials evaluating genetic therapies.1 passage
• Analysis of conference abstract-to-publication rate in UK orthopaedic research.1 passage
• Analysis of reports of unintended pregnancies associated with the combined use of non-enzyme-inducing antibiotics and hormonal contraceptives.1 passage
• Appropriately testing patients with intermediate risk for coronary artery disease: how well are we doing?1 passage
• Are CAR-T therapies living up to their hype? A study using real-world data in two cohorts to determine how well they are actually working in practice compared with bone marrow transplants.1 passage
• Assessing assumptions for statistical analyses in randomised clinical trials.1 passage
• Assessing the validity of surrogate endpoints in the context of a controversy about the measurement of effectiveness of hepatitis C virus treatment.1 passage
• Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how.1 passage
• Association of serum magnesium level change with in-hospital mortality.1 passage
• Association of study design features and treatment effects in trials of chronic medical conditions: a meta-epidemiological study.1 passage
• Asthma and COVID-19: review of evidence on risks and management considerations.1 passage
• Barriers and facilitators to knowledge transfer and exchange in palliative care research.1 passage
• Barriers to reporting guideline adherence in point-of-care ultrasound research: a cross-sectional survey of authors and journal editors.1 passage
• Bayesian interpretation of p values in clinical trials.1 passage
• Big data registries in spine surgery research: the lurking dangers.1 passage
• Biomarkers and outcomes of COVID-19 hospitalisations: systematic review and meta-analysis.1 passage
• Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports.1 passage
• Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study.1 passage
• Blood pressure-lowering treatment lowers mortality and cardiovascular disease risk, but whether effects differ at an arbitrary threshold of 140 mm Hg systolic blood pressure requires further research.1 passage
• Broad-spectrum antibiotics gave no clinical benefit and more adverse effects than narrow-spectrum antibiotics in treating acute respiratory tract infections in US children.1 passage
• Building capacity: getting evidence-based practice into healthcare professional curricula.1 passage
• COVID-19 and the US response: accelerating health inequities.1 passage
• Catalogue of bias: allocation bias.1 passage
• Catalogue of bias: attrition bias.1 passage
• Catalogue of bias: observer bias.1 passage
• Causal inference for clinicians.1 passage
• Challenges in interpreting results from 'multiple regression' when there is interaction between covariates.1 passage
• Characteristics and conflicts of interests of public speakers at the Psychopharmacologic Drug and Advisory Committee meetings regarding psychiatric drugs.1 passage
• Characteristics, quality and volume of the first 5 months of the COVID-19 evidence synthesis infodemic: a meta-research study.1 passage
• Claims of 'no difference' or 'no effect' in Cochrane and other systematic reviews.1 passage
• Clinical pathways on a mobile device.1 passage
• Clinical practice guideline adaptation methods in resource-constrained settings: four case studies from South Africa.1 passage
• Clinical trial registry use in minimally invasive surgical oncology systematic reviews and meta-analyses.1 passage
• Cochrane vertebroplasty review misrepresented evidence for vertebroplasty with early intervention in severely affected patients.1 passage
• Combination fixed-dose β agonist and steroid inhaler as required for adults or children with mild asthma: a Cochrane systematic review.1 passage
• Commitments by the biopharmaceutical industry to clinical trial transparency: the evolving environment.1 passage
• Completeness of reporting for systematic reviews of point-of-care ultrasound: a meta-research study.1 passage
• Consensus on evidence-based medicine curriculum contents for healthcare schools in Brazil.1 passage
• Considerations on the strengths and limitations of using disease-related mortality as an outcome in clinical research.1 passage
• Content analysis of clinical questions from Australian general practice which are prioritised for answering: identifying common question types and perceived knowledge gaps.1 passage
• Continuous outcome measures: conundrums and conversions contributing to clinical application.1 passage
• Conventional compared to network meta-analysis to evaluate antibiotic prophylaxis in patients with cancer and haematopoietic stem cell transplantation recipients.1 passage
• Coroners' concerns to prevent harms: a series of coroners' case reports to serve patient safety and educate the public, clinicians and policy-makers.1 passage
• Cross-sectional study of loss of life expectancy at different ages related to firearm deaths among black and white Americans.1 passage
• Determinants of inter-practice variation in ADHD diagnosis and stimulant prescribing: cross-sectional database study of a national surveillance network.1 passage
• Developing a fully automated evidence synthesis tool for identifying, assessing and collating the evidence.1 passage
• Developing tools to enhance the use of systematic reviews for clinical care in health systems.1 passage
• Development of a contemporary evidence-based practice workshop for health professionals with a focus on pre-appraised evidence and shared decision-making: a before-after pilot study.1 passage
• Development of five online modules for teaching evidence-informed healthcare: the West coast Interprofessional Clinical Knowledge Evidence Disseminator (WICKED) Project.1 passage
• Dietary Recommendations for Familial Hypercholesterolaemia: an Evidence-Free Zone.1 passage
• Digital aripiprazole or digital evergreening? A systematic review of the evidence and its dissemination in the scientific literature and in the media.1 passage
• Distance practical course on systematic reviews to support decisions of Brazilian regulatory agency for supplementary healthcare system.1 passage
• EMA's mishandling of an investigation into suspected serious neurological harms of HPV vaccines.1 passage
• Economic evaluation of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) for stroke prevention in patients with atrial fibrillation: a systematic review and meta-analysis.1 passage
• Educational strategies to enhance EBM teaching and learning in the workplace: a focus group study.1 passage
• Effect of spin in the abstract of a randomised controlled trial on physiotherapists' perception of treatment benefit: a randomised controlled trial.1 passage
• Effect size reporting among prominent health journals: a case study of odds ratios.1 passage
• Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis.1 passage
• Effectiveness of tests to detect the presence of SARS-CoV-2 virus, and antibodies to SARS-CoV-2, to inform COVID-19 diagnosis: a rapid systematic review.1 passage
• Efficacy and effectiveness studies of depression are not well-differentiated in the literature: a systematic review.1 passage
• Efficacy of reminders for increasing volunteer engagement in translating Cochrane plain language summaries: a pilot randomised controlled trial.1 passage
• Enabling individualised health in learning healthcare systems.1 passage
• Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression.1 passage
• European Recommendations for good practice in addition to an evidence-based guidelines programme: rationale and method of development.1 passage
• Evaluating the quality of systematic reviews and meta-analyses published on direct oral anticoagulants in the past 5 years.1 passage
• Evaluation of spin in abstracts of papers in psychiatry and psychology journals.1 passage
• Evaluation of the NCCN guidelines using the RIGHT Statement and AGREE-II instrument: a cross-sectional review.1 passage
• Evaluation of the completeness of intervention reporting in Cochrane surgical systematic reviews using the TIDieR-SR checklist: a cross-sectional study.1 passage
• Evidence maps: a tool to guide research agenda setting.1 passage
• Evidence synthesis software.1 passage
• Evidence synthesis workshops: moving from face-to-face to online learning.1 passage
• Evidence-based medicine and machine learning: a partnership with a common purpose.1 passage
• Evidence-based practice education for healthcare professions: an expert view.1 passage
• External validity, generalisability, applicability and directness: a brief primer.1 passage
• Face-to-face versus online clinically integrated EBM teaching in an undergraduate medical school: a pilot study.1 passage
• Framework for the synthesis of non-randomised studies and randomised controlled trials: a guidance on conducting a systematic review and meta-analysis for healthcare decision making.1 passage
• Guidelines do not self-implement: time for a research paradigm shift from massive creation to effective implementation in evidence-based medicine research in China.1 passage
• Gun safety discussions with caregivers: timing and demographic associations in a retrospective study.1 passage
• HOSPITAL Score, LACE Index and LACE+ Index as predictors of 30-day readmission in patients with heart failure.1 passage
• Heterogeneity of outcomes for intraoperative music interventions: a scoping review and evidence map.1 passage
• Hit or miss: the new cholesterol targets.1 passage
• How effective are 'age' tools at changing patient behaviour? A rapid review.1 passage
• How should we manage hip fracture patients on direct oral anticoagulants?1 passage
• Impact of oral anticoagulants on 30-day readmission: a study from a single academic centre.1 passage
• Implementing evidence-based medicine in a busy general hospital department: results and critical success factors.1 passage
• Improving the transparency of meta-analyses with interactive web applications.1 passage
• Inactivated trivalent influenza vaccination is associated with lower mortality among patients with COVID-19 in Brazil.1 passage
• Integrating evidence-based medicine skills into a medical school curriculum: a quantitative outcomes assessment.1 passage
• Intention of German non-medical staff in preclinical emergency and rescue medicine to graduate from an academic programme in emergency paramedics: a structural equation analysis based on the theory of planned behaviour of Icek Ajzen.1 passage
• Interactive visualisation for interpreting diagnostic test accuracy study results.1 passage
• Intervention reporting of clinical trials published in high-impact cardiology journals: effect of the TIDieR checklist and guide.1 passage
• Interventions for Menière's disease: an umbrella systematic review.1 passage
• Is there a genuine placebo effect in acute depression treatments? A reassessment of regression to the mean and spontaneous remission.1 passage
• Is there a smoker's paradox in COVID-19?1 passage
• Items for consideration in a reporting guideline for mediation analyses: a Delphi study.1 passage
• Ivabradine added to usual care in patients with heart failure: a systematic review with meta-analysis and trial sequential analysis.1 passage
• Key Concepts for Informed Health Choices: a framework for helping people learn how to assess treatment claims and make informed choices.1 passage
• Lack of effects of evidence-based, individualised counselling on medication use in insured patients with mild hypertension in China: a randomised controlled trial.1 passage
• Later is not necessarily better: limitations of survival analysis in studies of long-term drug treatment of psychiatric conditions.1 passage
• Lessons learnt on transparency, scientific process and publication ethics. The short story of a long journey to get into the public domain unpublished data, methodological flaws and bias of the Cochrane HPV vaccines review.1 passage
• Limited engagement with transparent and open science standards in the policies of pain journals: a cross-sectional evaluation.1 passage
• Make quotations great again: a proposal to reduce false-knowledge.1 passage
• Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be.1 passage
• Methodological quality and redundancy of systematic reviews that compare endarterectomy versus stenting for carotid stenosis.1 passage
• Methylphenidate for ADHD rejected from the WHO Essential Medicines List due to uncertainties in benefit-harm profile.1 passage
• NICE rapid guidelines: exploring political influence on guidelines.1 passage
• Natriuretic peptide-guided treatment for heart failure: a systematic review and meta-analysis.1 passage
• Online supplementation for teaching evidence-based medicine: feasibility of a randomised-controlled trial.1 passage
• Open-label placebo clinical trials: is it the rationale, the interaction or the pill?1 passage
• Optimising the process for conducting scoping reviews.1 passage
• Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics.1 passage
• Patients' participation in government-sponsored guidelines in Latin America: a cross-sectional study.1 passage
• Perfect Top of the Evidence Hierarchy Pyramid, Maybe Not So Perfect: lessons learned by a novice researcher engaging in a meta-analysis project.1 passage
• Pivmecillinam is more effective than ibuprofen in symptom resolution in women with uncomplicated urinary tract infection: antibiotic treatment for UTI is important.1 passage
• Postmarketing studies: can they provide a safety net for COVID-19 vaccines in the UK?1 passage
• Prevention of cardiovascular disease and renal failure in type 2 diabetes: sodium-glucose cotransporter-2 (SGLT2) inhibitors.1 passage
• Prevention of exacerbations in patients with stable non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis of pharmacological and non-pharmacological therapies.1 passage
• Problem with patient decision aids.1 passage
• Public awareness of the National Suicide Prevention Lifeline following the release of a hip-hop song.1 passage
• Publication by association: how the COVID-19 pandemic has shown relationships between authors and editorial board members in the field of infectious diseases.1 passage
• Quality of early evidence on the pathogenesis, diagnosis, prognosis and treatment of COVID-19.1 passage
• Quality of systematic reviews supporting the 2017 ACC/AHA and 2018 ESC/ESH guidelines for the management of hypertension.1 passage
• Reducing overuse by recognising the unintended harms of good intentions.1 passage
• Research integrity and the law that never was.1 passage
• Rivaroxaban plus aspirin, compared with aspirin alone, reduced cardiovascular events in patients with stable peripheral or carotid artery disease, but increased the risk of major bleeding.1 passage
• Shared decision making for thromboembolic prophylaxis in non-valvular atrial fibrillation: promise and problems with the American College of Cardiology's AnticoagEvaluator (based on SPARCtool).1 passage
• Short and long-term psychosocial consequences of participating in a colorectal cancer screening programme: a matched longitudinal study.1 passage
• Should antidepressants be used for major depressive disorder?1 passage
• Single-dose fosfomycin is less effective than 5-day nitrofurantoin in women with uncomplicated urinary tract infection: closing the evidence gap for a new recommendation of an old antibiotic.1 passage
• Statins for primary prevention: what is the regulator's role?1 passage
• Students 4 Best Evidence as a digital Problem-Based Learning method to improve Evidence-Based Practice competencies in undergraduate physiotherapy students: an observational study.1 passage
• Subduing the killer - sepsis; through simulation.1 passage
• Successes, lessons and opportunities: 15-year follow-up of an integrated evidence-based medicine curriculum.1 passage
• Synergistic effects of blood pressure-lowering drugs and statins: systematic review and meta-analysis.1 passage
• Systematic benefit-risk assessment for buprenorphine implant: a semiquantitative method to support risk management.1 passage
• TIDieR checklist evaluation of clinical trial intervention reporting for recent FDA-approved anticancer medications.1 passage
• Teaching clinicians shared decision making and risk communication online: an evaluation study.1 passage
• Teaching evidence-based medicine application: transformative concepts of information mastery that foster evidence-informed decision-making.1 passage
• Ten years later: a review of the US 2009 institute of medicine report on conflicts of interest and solutions for further reform.1 passage
• The effect of publication bias magnitude and direction on the certainty in evidence.1 passage
• The magnitude of small-study effects in the1 passage
• The need for clinical judgement in the application of evidence-based medicine.1 passage
• Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances.1 passage
• Training curriculum to help patient representatives participate meaningfully in the development of clinical practice guidelines.1 passage
• Translation of Oxford's CEBM catalogue of bias into Portuguese: contributing to the dissemination of conscientious thinking on health research.1 passage
• Transparency of results reporting for depression treatment studies in ClinicalTrials.gov: a cross-sectional study.1 passage
• Treating schizophrenia: the quality of evidence behind treatment recommendations and how it can improve.1 passage
• Trial design for ineffectiveness research: a mixed-methods survey.1 passage
• Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia in older adults compared with other antibiotics used to treat UTIs.1 passage
• Twenty-four-hour ambulatory systolic blood pressure may be a better predictor of all-cause and cardiovascular mortality than clinic blood pressure.1 passage
• Use of modified intention-to-treat analysis in studies of direct oral anticoagulants and risk of selection bias: a systematic review.1 passage
• Using routine databases to evaluate Electronic Palliative Care Co-ordination Systems (EPaCCS).1 passage
• Using the evidence-based medicine and evidence-based management to minimise overuse and maximise quality in healthcare: a hybrid perspective.1 passage
• Variation in analytic transparency in recent efficacy studies of antidepressant medication.1 passage
• Was amorphous aluminium hydroxyphosphate sulfate adequately evaluated before authorisation in Europe?1 passage
• When to include clinical study reports and regulatory documents in systematic reviews.1 passage