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Necrotic lipoma at the posterior thigh mimicking liposarcoma. A lipoma is one of the most common benign tumours and can develop at any location in the body. Lipomas present characteristic imaging features; hence, they are easy to identify on CT and MRI. However, cases of necrotic lipoma are rarely encountered; therefore, information on the imaging findings of necrotic lipomas is scarce. In the present report, we describe the case of a 63-year-old man with necrotic lipoma in the deep layer of the posterior thigh, which resembled a liposarcoma on imaging. To the best of our knowledge, only a few reports on necrotic lipoma on the extremities have been published.