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abstractpubmed· Abstract 2020· item PMID:33038919

Capillary blood reference intervals for platelet parameters in healthy full-term neonates in China. BACKGROUND: No consensus has been reached on capillary blood reference intervals for platelet parameters in full-term neonates. We aimed to establish neonatal capillary blood reference intervals for platelet parameters and evaluate influences of sex, gestational age and postnatal age on platelet parameters. METHODS: This study was a prospective investigation and implemented in 594 healthy full-term neonates from 12 to 84 h of age, using SYSMEX XN-9000 haematology automatic analyser by means of capillary blood. Reference intervals for platelet parameters were defined by an interval of 2.5th - 97.5th percentiles. RESULTS: Capillary reference interval for platelet count was (152-464) × 109/L. No significance was found between sex-divided reference intervals for platelet parameters. The values of platelet count changed minimally across gestational age (37-41 weeks) and postnatal age (12-84 h). Reference intervals for other platelet parameters were affected by these factors to a different extent. CONCLUSIONS: We established capillary blood reference intervals for platelet parameters in the first days after birth of full-term neonates in China.