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abstractpubmed· Abstract 2017· item PMID:25487369

Aflibercept-related nasal septum perforation. Hypertension, cytopenia and diarrhea are the most common side effects of aflibercept. Rarely thromboembolism, hemorrhage, fistulization and reversible posterior leukoencephalopathy have been reported. Here we report a patient experiencing nasal septum perforation during aflibercept therapy.